Antioxidant activity and possible bioactive components in hydrophilic and lipophilic fractions from the seaweed Halimeda incrassata

Abstract

Hydrophilic and lipophilic fractions, obtained from the marine algae Halimeda incrassata (J.Ellis) J.V.Lamouroux, Halimedaceae, were studied by using the β-carotene-linoleate assay system. In case of hydrophilic fractions, the total phenolic compounds were quantified and two of their components were identified as salicylic and ferulic acids. From the lipophilic fraction, fatty acid composition was studied. The highest antioxidant activities values were found on the polar fractions containing phenolic acids. The total phenolics content on the hydrophilic fractions was 255 µg of gallic acid equivalents/g of fresh seaweed. To further characterize H. incrassata chemical composition, the total lipid content was quantified (7.4 mg per gram of dried algae) as well as the saturated and unsaturated fatty acids ratio (1:1.46). In summary, this paper adds more convincing evidences in support of the antioxidant abilities of the lyophilized aqueous extract of Halimeda incrassata and it also relates this bioactivity, for the first time, with particular phenolic components of the extract. Altogether, these results represent another step towards the use of this natural product as drug candidates.

Cytotoxicity, Antioxidants and Antimicrobial Activities of Lipids Extracted from Some Marine Algae

“…Similar results were obtained from lipids of brown algae Sargassum marginatum, which possessed an inhibition effect against human pro-melocytic leukemia [7]. Lipid extracts of Ginseng marc showed a potent inhibitory activity These results are similar to that obtained by Chirasuwan [22], they found that lipid extracts of S. platensis possessed antiviral activity against HSV-1 with an IC50 value of 25.1 μg/ml. On the other hand, the 1-docosanol (C22:0) was found to inhibit viral replication by interfering with the early intracellular events surrounding viral entry into target cells.…”

Methanol extracts from Cystoseira tamariscifolia and Cystoseira nodicaulis are able to inhibit cholinesterases and protect a human dopaminergic cell line from hydrogen peroxide-induced cytotoxicity

“…Cystoseira tamariscifolia was particularly enriched in hydroxycinnamic acids. Hydroxycinnamic acids including ferulic, caffeic, sinapic and p-coumaric acids are phenolic compounds widely distributed in plants and also present in algae (Shahidi & Chandrasekara 2010;Novoa et al 2011). These compounds display a strong anti-radical activity, which is related to their capacity to donate hydrogen or electron, and to delocalise/stabilise the resultant phenoxyl radical (Teixeira et al 2013).…”

Potential benefits of polysaccharides derived from marine alga Ulva lactuca against hepatotoxicity and nephrotoxicity induced by thiacloprid, an insecticide pollutant

“…These alternatives are efficient supplements to standard medication revelation and chemical drugs to the point that efforts are being deployed to standardize plant based prescriptions . Among these, numerous marine resources such as seaweeds have bioactive compounds that can be used in new drugs and as healthy food additives through their beneficial dietary fibers …”

“…13 Among these, numerous marine resources such as seaweeds have bioactive compounds that can be used in new drugs and as healthy food additives through their beneficial dietary fibers. 14,15 Ulva lactuca (U. lactuca) is one of the most common green macroalgae throughout the world. 16 Despite its abundance, it is poorly valued 17 and only a small part of its biomass is used as food or animal feed, 18 organic crop fertilizer, 19 effluent biofilter 20 and more recently, as protectant.…”