Revisão da Maytenus ilicifolia Mart. ex Reissek, Celastraceae. Contribuição ao estudo das propriedades farmacológicas

Santos-Oliveira, Ralph; Coulaud-Cunha, Simone; Colaço, Waldeciro

doi:10.1590/s0102-695x2009000400025

Cited by 45 publications

(33 citation statements)

References 30 publications

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“…To this end, two plants were selected -Cassia angustifolia Vahl, Fabaceae, and Maytenus ilicifolia (Schrad.) Planch., Celastraceae, -that are used medicinally worldwide (Silva et al, 2004;Santos-Oliveira et al, 2009). …”

Section: Introductionmentioning

confidence: 99%

Co-processed extracts of Cassia angustifolia Vahl, Fabaceae, and Maytenus ilicifolia (Schrad.) Planch., Celastraceae, for production of high load tablets

Alves¹,

Barreto²,

Souza³

et al. 2011

Rev. bras. farmacogn.

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Abstract:The aim of this study was to investigate the feasibility of a co-processing technique for improving the manufacturing properties of Maytenus ilicifolia (Schrad.) Planch., Celastraceae, and Cassia angustifolia Vahl, Fabaceae, extracts in order to obtain tablets containing a high dose of such extracts. An experimental mixture design was used to optimise the formulation composition. Flowability parameters, such as compressibility index, time flow and angle of repose, were determined. Additional important industrial parameters, such as granulometry, bulk density and moisture stability, were also studied. The results demonstrated that co-processing technique was able to improve the flowability of vegetal extracts, making these materials suitable for a direct compression process. The contour plots revealed that formulations with a higher amount of lactose produced the best flow results as well as a larger particle size and a greater bulk density. Tablets from co-processed extracts containing lactose as majority diluent showed appropriate physical-chemical characteristics and presented a more stable moisture sorption behaviour compared to commercial gelatine capsules.

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Section: Introductionmentioning

confidence: 99%

Co-processed extracts of Cassia angustifolia Vahl, Fabaceae, and Maytenus ilicifolia (Schrad.) Planch., Celastraceae, for production of high load tablets

Alves¹,

Barreto²,

Souza³

et al. 2011

Rev. bras. farmacogn.

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“…Revisando as referidas publicações e em concordância com Santos-Oliveira et al (2009), técnicas de plantio padronizadas e seguras devem ser preconizadas já que alterações inclusive em seu ciclo de plantio podem resultar em alterações nas concentrações e até o desaparecimento de constituintes, dentre eles os que possuem ação terapêutica, o princípio ativo da planta, ou mesmo o aparecimento de substâncias indesejáveis.…”

Section: Tabela 2 Teor De Polifenóis Totais E Taninos Das Espécies Munclassified

Comparação do teor de taninos entre duas espécies de espinheira-santa (Maytenus aquifolium Mart.e Maytenus ilicifolia Mart. ex Reissek)cultivadas no Horto Medicinal do Refúgio Biológico Bela Vista - RBBV da Itaipu Binacional - Foz do Iguaçu, PR - Brasil.

Holnik

Hussein

Souza

et al. 2015

Rev. bras. plantas med.

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Recebido para publicação em 29/11/2012 Aceito para publicação em 24/07/2014 RESUMO: As duas espécies de espinheira-santa Maytenus aquifolium Mart. e Maytenus ilicifolia Mart. ex Reissek pertencentes à família Celastraceae e têm sido intensamente exploradas nas populações nativas devido seu alto valor medicinal. O grande interesse pela espinheira-santa é para o tratamento de gastrites, úlceras gástricas e duodenais. O efeito antiulcerogênico está relacionado com a presença de polifenóis totais, mais especificamente com os taninos. Este trabalho teve como objetivo comparar o teor de taninos entre essas duas espécies cultivadas no Horto Medicinal do Refúgio Biológico Bela Vista -RBBV da Itaipu Binacional no município de Foz do Iguaçu, PR -Brasil. Foram realizadas duas coletas com intervalo de um mês para cada espécie e para a quantificação foi realizada a análise por espectrofotometria segundo a Farmacopeia Brasileira V. Os resultados foram analisados através do teste de variância (ANOVA) e a diferença no teor de taninos foi evidenciada pelo teste Tukey, a 5% de nível de significância empregando-se o software SISVAR. Foram obtidos em média 0,61% para o lote 1 e 2 de Maytenus aquifolium e (3,90%) para Maytenus ilicifolia, resultando em uma média de 84,35% de taninos a mais para Maytenus ilicifolia em comparação com Maytenus aquifolium concluindo assim que as espécies não devem ser intercambiáveis.Palavras chave: Espinheira-santa, tratamento de gastrite, polifenóis totais, análise espectrofotométrica. ABSTRACT: Comparison of the tannin doses between two species of thorn-santa (Maytenus ilicifolia Mart. and Maytenus aquifolium Mart. ex Reissek) grown in the medicinal garden of Bela Vista Biological Refuge -RBBV of Itaipu Binational -Foz doIguacu, PR -Brazil. The two species of (espinheira-santa) Maytenus aquifolium and Maytenus ilicifolia, which belong to the Celastraceae family, have been intensively explored in native populations, due to its medicinal potential. The great interest in the espinheira-santa is due to its effectiveness on the treatment of gastritis, gastric and duodenal ulcers. The antiulcerogenic effect is related to the presence of phenolic compounds, more specifically the tannins. This study aimed to compare the tannin doses between these two species grown in the Medicinal Garden of Bela Vista Biological Refuge -RBBV of Itaipu in the city of Foz do Iguaçu, PR -Brazil. Two trials were conducted with one month interval, for the quantification of the tannins by a spectrophotometry, according to the Brazilian Pharmacopoeia V. The results were analyzed through the analysis of variance (ANOVA) and the difference in the tannins doses was demonstrated in a Tukey test at 5% level of significance employing the SISVAR software. It were found 0.61% of tannins for lot 1 and 2 of Maytenus aquifolium, and 3.90% for Maytenus ilicifolia, which represents 84.35% more tannin at Maytenus ilicifolia than at Maytenus aquifolium. Therefore, the species should not be interchanged.

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“…There are 77 Maytenus species in the Brazilian flora (Carvalho-Okano 1992), some of which have pharmacological and antioxidant properties (Corsino et al 2003;Pereira et al 2005;Tiberti et al 2007;Santos-Oliveira et al 2009;Cansian et al 2015;Santoyo et al 2015;Bevenutti et al 2016).…”

Section: Introductionmentioning

confidence: 99%

Genetic diversity in populations of Maytenus dasyclada (Celastraceae) in forest reserves and unprotected Araucaria forest remnants

et al. 2017

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Understanding the genetic structure and diversity of plants is fundamental to their conservation and permits their sustainable use by local communities. Th e genus Maytenus (Celastraceae) is composed of plants possessing pharmacological and antioxidant properties. However, the genetic and economic properties of the species M. dasyclada, a typical species of Araucaria forests in Brazil and Uruguay, have been little studied. In this work, the genetic structure and diversity of natural populations of M. dasyclada located in unprotected and preserved forest remnants were investigated using RAPD and isozymes markers. Th e results demonstrated that in areas of preservation, populations of M. dasyclada possess a relatively high degree of polymorphism and high values for Na, Ne, Shannon index, He and Ho, indicating high genetic variability. Moreover, these protected populations are very close to each other and potentially experience signifi cant gene fl ow. Th e results presented here highlight the relevance of preservation areas for the conservation of M. dasyclada, and that populations inhabiting these areas could serve as a genetic source for the recovery of populations in regions where genetic diversity has been lost.

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Revisão da Maytenus ilicifolia Mart. ex Reissek, Celastraceae. Contribuição ao estudo das propriedades farmacológicas

Cited by 45 publications

References 30 publications

Co-processed extracts of Cassia angustifolia Vahl, Fabaceae, and Maytenus ilicifolia (Schrad.) Planch., Celastraceae, for production of high load tablets

Co-processed extracts of Cassia angustifolia Vahl, Fabaceae, and Maytenus ilicifolia (Schrad.) Planch., Celastraceae, for production of high load tablets

Comparação do teor de taninos entre duas espécies de espinheira-santa (Maytenus aquifolium Mart.e Maytenus ilicifolia Mart. ex Reissek)cultivadas no Horto Medicinal do Refúgio Biológico Bela Vista - RBBV da Itaipu Binacional - Foz do Iguaçu, PR - Brasil.

Genetic diversity in populations of Maytenus dasyclada (Celastraceae) in forest reserves and unprotected Araucaria forest remnants

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