Flavonoids, benzophenones and a new euphane derivative from Clusia columnaris Engl.

Abstract

RESUMO: "Flavonóides, benzofenonas e um novo eufano de Clusia columnaris Engl.". Dos frutos de Clusia columnaris foram isoladas as benzofenonas poliisopreniladas machuona e clusiacromeno A. Do extrato em hexano obtido de galhos e folhas novas, um novo triterpeno do tipo eufano foi isolado. Sua estrutura foi elucidada através de métodos espectroscópicos. Por outro lado, dos extratos mais polares -em acetato de etila e em butanol, foram isolados os fl avonóides C-glicosilados isovitexina, vitexina e vitexina-2"-xilosídeo, além de sete bisfl avonóides conhecidos como bisfl avonóides do grupo da Garcinia.Unitermos: Clusia columnaris, Guttiferae, eufanos, fl avonóides C-glucosídicos, bisfl avonóides. ABSTRACT:The polyisoprenylated benzophenones machuone and clusiachromene A have been isolated from the fruits of Clusia columnaris. The hexane extract of the young branches with leaves afforded a new euphane derivative, whose structure was elucidated by spectroscopic methods. On the contrary, the most polar EtOAc and ButOH extracts were constituted of fl avonoid C-glucosides (isovitexin, vitexin and vitexin-2"-xyloside) and seven bifl avonoids of the so-called Garcinia group.

Distribution of metabolites in galled and non-galled leaves of Clusia lanceolata and its antioxidant activity

“…The occurrence of C-glycosylated flavones has been described for other species of the genus Clusia (Delle Monache, 1991;Chedier et al, 1999;Compagnone et al, 2008). Thus, this study contributes to the knowledge of chemosystematics of this genus.…”

Complete NMR assignments of bioactive rotameric (3 → 8) biflavonoids from the bark of Garcinia hombroniana

“…Based on the comparison of 1D and 2D NMR data of the compounds 2–7 with the published literature, they were identified as volkensiflavone ( 2 ), 4″‐ O ‐methyl‐volkensiflavone ( 3 ), volkensiflavone‐7‐ O ‐glucopyranoside ( 4 ), morelloflavone ( 5 ), 3″‐ O ‐methyl‐morelloflavone ( 6 ) and morelloflavone‐7‐ O ‐glucopyranoside ( 7 ) . Their 1 H and 13 C NMR spectra and complete assignments given in Figs S15–S20 and Tables S1–S6 are shown in the Supporting Information.…”

In vitro gastrointestinal biotransformation and characterization of a Desmodium adscendens decoction: the first step in unravelling its behaviour in the human body

“…Glucose was directly attached to the C‐8 of the aglycon as can be observed in the HMBC spectrum by the correlation between Glu H‐1 and C‐8. Correlations in the HMBC and COSY spectra showed that xylose was attached to glucose by a 1 → 2 glycosidic bond . Based on these results, compound 6 was elucidated as 2″‐ O ‐xylosyl‐vitexin ( 6 ) (Figure ).…”