Caracterização farmacognóstica de pau d'alho Gallesia integrifolia (Spreng.) Harms

Akisue, Maria Kubota; Akisue, Gokithi; Oliveira, Fernando de

doi:10.1590/s0102-695x1986000200007

Cited by 12 publications

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“…The major compounds were 2,8-dithianonane (52.9%), dimethyl trisulfide (15.2%), and lenthionine (14.8%) (Table S1; Figures S1-S4). The presence of sulfureted compounds in the essential oil is related to the characteristic alliaceous odor (Akisue et al 1986). The results found in the present study are in agreement with Raimundo et al (2018).…”

Section: Resultsmentioning

confidence: 99%

Cytotoxicity and anti-inflammatory activities of Gallesia integrifolia (Phytolaccaceae) fruit essential oil

Bortolucci

Raimundo

Fernandez

et al. 2021

Natural Product Research

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The chemical composition of Gallesia integrifolia fruits essential oil was obtained by hydrodistillation using a modified Clevenger apparatus was investigated by gas chromatography coupled to mass spectrometry (GC/MS). In addition, the cytotoxicity activity against human tumor cell lines MCF-7 (breast adenocarcinoma), NCI-H460 (large cell lung carcinoma), HeLa (cervical carcinoma), and HepG2 (hepatocellular carcinoma), and non-tumor PLP2 (porcine liver primary cells) as well as the anti-inflammatory action was proposal. The compounds were predominantly organosulfates (2,8-dithianonane, dimethyl trisulfide, and lenthionine). Antiinflammatory activity that provides 50% inhibition of nitric oxide production (55 mg/mL) of essential oil of the fruits. It also presents cytotoxic activity against MCF-7 (GI 50 ¼ 66 mg/mL), NCI-H-460 (GI 50 ¼ 147 mg/mL), HeLa (GI 50 ¼ 182 mg/mL) and HepG2 (GI 50 ¼ 240 mg/mL). The essential oil is more active in tumor cells than in non-tumor cells and the GI 50 values for essential oil reported in our work support future studies.

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Section: Resultsmentioning

confidence: 99%

Cytotoxicity and anti-inflammatory activities of Gallesia integrifolia (Phytolaccaceae) fruit essential oil

Bortolucci

Raimundo

Fernandez

et al. 2021

Natural Product Research

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“…Schmidt) Nowicke belong to Phytolaccaceae family 1 . This tree is popularly known as pau d’alho (common name in Portuguese) and is native to Brazil, from the states of Ceará to Paraná 2, 3. In popular medicine, the bark of this species is utilized to prepare teas for the flu, coughing, pneumonia, vermin, gonorrhea, prostate tumors and rheumatism 4 .…”

Section: Introductionmentioning

confidence: 99%

Antifungal activity of Gallesia integrifolia fruit essential oil

Raimundo

Bortolucci

Glamočlija

et al. 2018

Brazilian Journal of Microbiology

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Gallesia integrifolia (Phytolaccaceae) is native to Brazil and has a strong alliaceous odor. The objective of this study was to identify the chemical composition of G. integrifolia fruit essential oil and evaluate fungicidal activity against the main food-borne diseases and food spoilage fungi. The essential oil was extracted by hydrodistillation and identified by GC-MS. From 35 identified compounds, 68% belonged to the organosulfur class. The major compounds were dimethyl trisulfide (15.49%), 2,8-dithianonane (52.63%) and lenthionine (14.69%). The utilized fungi were Aspergillus fumigatus, Aspergillus niger, Aspergillus ochraceus, Aspergillus versicolor, Penicillium funiculosum, Penicillium ochrochloron, Penicillium verrucosum var. cyclopium, and Trichoderma viride. Minimal fungicidal concentration for the essential oil varied from 0.02 to 0.18mg/mL and bifonazole and ketoconazole controls ranged from 0.20 to 3.50mg/mL. The lower concentration of the essential oil was able to control P. ochrochloron, A. fumigatus, A. versicolor, A. ochraceus and T. viride. This study shows a high fungicidal activity of G. integrifolia fruit essential oil and can support future applications by reducing the use of synthetic fungicides.

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“…The plant leaves are elliptical and shiny, flowers are bunchy and white which bloom from February to April. Its elongated samara-like fruits become brownish when ripening from June to October; and it is difficult to separate the seed from the fruit (Akisue et al, 1986;Duringan et al, 1997). Gallesia integrifolia also produces wood for several uses.…”

Section: Introductionmentioning

confidence: 99%

Chemical composition of garlic wood (Gallesia integrifolia) (Phytolaccaceae) volatile compounds and their activity on cattle tick

Raimundo¹,

Bortolucci²,

Silva³

et al. 2017

Aust J Crop Sci

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The objective of this study was to evaluate the acaricidal and larvicidal activities of essential oil (EO) from fruits, leaves and flowers of garlic wood on cattle tick [Rhipichephalus (Boophilus) microplus]. The fruits were harvested from May to June (2015) and the leaves and flowers in December (2015). The EO was obtained by hydrodistillation (2h) and identified by GC/MS. Bioassays consisted of Adult Immersion Test and Larval Immersion Test. The results made the following major compounds evident: 2,3,5-trithiahexane (35.29%) in fruits, dimethyl sulfide (42.42%) in leaves and methanethiol (44.91%) in flowers. The EOs from fruits, leaves and flowers showed high activity on the tick larval cycle, presenting LD 99.9 of (0.23 ± 0.01 mg/mL), (2.15 ± 0.11 mg/mL) and (0.08 ± 0.00 mg/mL), respectively. However, when we compared different phases of cattle tick's live cycle, EO from fruits was more active on females' mortality, and EO from leaves was more efficient on the egg hatching inhibition, whereas EO from flowers presented better results on bovine tick larva. Thus, garlic wood (Gallesia integrifolia), a native plant of the Atlantic forest can be considered as a promising natural agent to control bovine tick.

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Caracterização farmacognóstica de pau d'alho Gallesia integrifolia (Spreng.) Harms

Cited by 12 publications

References 0 publications

Cytotoxicity and anti-inflammatory activities of Gallesia integrifolia (Phytolaccaceae) fruit essential oil

Cytotoxicity and anti-inflammatory activities of Gallesia integrifolia (Phytolaccaceae) fruit essential oil

Antifungal activity of Gallesia integrifolia fruit essential oil

Chemical composition of garlic wood (Gallesia integrifolia) (Phytolaccaceae) volatile compounds and their activity on cattle tick

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