Upper esophageal sphincter resting pressure varies during esophageal manometry

Abstract

BackgroundThe upper esophageal sphincter is composed of striated muscle. The stress of intubation and the need to inhibit dry swallows during an esophageal manometry test may lead to variations in basal pressure of this sphincter. Upper esophageal sphincter is usually only studied at the final part of the test. Was observed during the performance of high resolution manometry that sphincter pressure may vary significantly over the course of the test.AimTo evaluate the variation of the resting pressure of the upper esophageal sphincter during high resolution manometry.MethodsWas evaluated the variation of the basal pressure of the upper esophageal sphincter during high resolution manometry. Were reviewed the high resolution manometry tests of 36 healthy volunteers (mean age 31 years, 55% females). The basal pressure of the upper esophageal sphincter was measured at the beginning and at the end of a standard test.ResultsThe mean time of the test was eight minutes. The basal pressure of the upper esophageal sphincter was 100 mmHg at the beginning of the test and 70 mmHg at the end (p<0.001). At the beginning, one patient had hypotonic upper esophageal sphincter and 14 hypertonic. At the end of the test, one patient had hypotonic upper esophageal sphincter (same patient as the beginning) and seven hypertonic upper esophageal sphincter.ConclusionA significant variation of the basal pressure of the upper esophageal sphincter was observed in the course of high resolution manometry. Probably, the value obtained at the end of the test may be more clinically relevant.

Preoperative Manometry for the Selection of Obese People Candidate to Sleeve Gastrectomy

“…A control group was constituted in this research, due to the fact that manometric changes in the esophagus can occur in non-obese asymptomatic individuals 13 , 14 , 24 , 25 .…”

The effect of position on esophageal structure and function determined with solid‐state high‐resolution manometry

“…The reason for this finding may be related to the fact that UES is composed of striated muscle. Thus, the measurement of UES pressure was influenced by multifactors, such as head position, 13,20 patient's age 21 and the stress of intubation 22 . Consistent with our findings, previous studies have also demonstrated significant variation in UES pressure.…”

A Pictorial Presentation of Esophageal High Resolution Manometry Current Parameters

“…Version 3.0 is more clinical-oriented. A new version is anticipated for next year including the upper esophageal sphincter since this technology seems to be extremely advantageous for the study of this area 15 . …”