Paracoccidioidomycosis mortality in the State of Paraná, Brazil, 1980/1998

Abstract

The paracoccidioidomycosis mortality rate in the State of Paraná, Brazil (1980/1998) was analyzed using the death registry data from the Brazilian Mortality Information System and the estimated population from the Brazilian Institute of Geography and Statistics. To qualify the deaths, we deployed ICD-9 for 1980/1995 and ICD-10 for the more recent years. During this period there were 551 deaths from paracoccidioidomycosis in the State of Paraná. Most of the deaths were in male in the 30-59-year age group. The average annual mortality rate was 3.48 per million inhabitants, showing a tendency to stabilize during the study period. Paracoccidioidomycosis was the fifth cause of mortality among the predominantly chronic infectious diseases and had the highest mortality rate among the systemic mycoses. Paracoccidioidomycosis was observed in 184 counties in the State of Paraná. Most deaths were recorded in the North-Central meso-region, and the highest mortality rate occurred in the West meso-region.

Occurrence of 102 cases of paracoccidioidomycosis in 18 months in the Itaipu Lake region, Western Paraná

“…In the State of São Paulo, from 1985 to 2005, lower rates of mortality of 2.28 deaths per 1 million inhabitants were reported 1 . In the State of Paraná, from 1980 to 1998, an annual mortality rate of 3.48 deaths per million inhabitants was determined, which meant the state was first in PCM mortality in Brazil 13 .…”

Fungal Colitis by Paracoccidioides brasiliensis: a case report

“…PBM is considered the most important fungal infection in Latin America, with the incidence of 1 to 3 per 100,000 inhabitants in endemic areas 2 , occurring from Southern Mexico to Northern Argentina 7 . Individuals affected by the disease are mostly men who live and/or develop activities in rural areas 1,8 , between 30 and 59 years old [4][5][6]9 . The social and economic costs incurred with the debilitation of individuals in their most productive phase and extended treatment, as well as the frequent sequelae that can lead to early death when not opportunely diagnosed and treated 10,11 , ensure high epidemiological relevance to this pathology.…”

Perfil clínico, laboratorial e epidemiológico de pacientes com paracoccidioidomicose em um serviço de referência no noroeste do estado do Paraná

“…No Paraná, é a quinta causa de morte nesse grupo de doenças (6) , e a taxa de mortalidade média anual é de 3,48 por milhão de habitantes, sendo considerada a mais alta taxa de mortalidade entre as micoses sistêmicas (7) . A sintomatologia da PCM é muito variável, nem sempre apresenta quadro clínico típico, por depender da fase da doença e da extensão das lesões (8) .…”