The Pelotas birth cohort study, Rio Grande do Sul, Brazil, 1982-2001

Victora, César G.; Barros, Fernando C.; Lima, Rosângela C; Béhague, Dominique P.; Gonçalves, Helen; Horta, Bernardo Lessa; Gigante, Denise Petrucci; Vaughan, J. G.

doi:10.1590/s0102-311x2003000500003

Cited by 107 publications

(62 citation statements)

References 20 publications

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“…The new analyses presented here are based on the cohorts in Brazil, 6 Guatemala, 7,8 India, 9,10 the Philippines, 11 and South Africa 12 (table 1). Panel 1 shows the exposures that were assessed.…”

Section: New Data Analysesmentioning

confidence: 99%

Maternal and child undernutrition: consequences for adult health and human capital

et al. 2008

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SummaryIn this paper we review the associations between maternal and child undernutrition with human capital and risk of adult diseases in low-income and middle-income countries. We analysed data from five long-standing prospective cohort studies from Brazil, Guatemala, India, the Philippines, and South Africa and noted that indices of maternal and child undernutrition (maternal height, birthweight, intrauterine growth restriction, and weight, height, and body-mass index at 2 years according to the new WHO growth standards) were related to adult outcomes (height, schooling, income or assets, offspring birthweight, body-mass index, glucose concentrations, blood pressure). We undertook systematic reviews of studies from low-income and middle-income countries for these outcomes and for indicators related to blood lipids, cardiovascular disease, lung and immune function, cancers, osteoporosis, and mental illness. Undernutrition was strongly associated, both in the review of published work and in new analyses, with shorter adult height, less schooling, reduced economic productivity, and—for women—lower offspring birthweight. Associations with adult disease indicators were not so clear-cut. Increased size at birth and in childhood were positively associated with adult body-mass index and to a lesser extent with blood pressure values, but not with blood glucose concentrations. In our new analyses and in published work, lower birthweight and undernutrition in childhood were risk factors for high glucose concentrations, blood pressure, and harmful lipid profiles once adult body-mass index and height were adjusted for, suggesting that rapid postnatal weight gain—especially after infancy—is linked to these conditions. The review of published works indicates that there is insufficient information about long-term changes in immune function, blood lipids, or osteoporosis indicators. Birthweight is positively associated with lung function and with the incidence of some cancers, and undernutrition could be associated with mental illness. We noted that height-for-age at 2 years was the best predictor of human capital and that undernutrition is associated with lower human capital. We conclude that damage suffered in early life leads to permanent impairment, and might also affect future generations. Its prevention will probably bring about important health, educational, and economic benefits. Chronic diseases are especially common in undernourished children who experience rapid weight gain after infancy.

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Section: New Data Analysesmentioning

confidence: 99%

Maternal and child undernutrition: consequences for adult health and human capital

et al. 2008

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“…It could be argued that these studies did not take into account the year of birth, also known as the cohort effect. 18 The 1982 Pelotas Birth Cohort Study 24,25 provided good quality of data to the present study. However, there are some limitations: no data on length measurement at birth and no follow-up near menarche age for all girls.…”

Section: Discussionmentioning

confidence: 90%

“…The cohort subjects have been followed up in several studies and detailed information are available elsewhere. 24,25 The present study included 2,084 women with information on menarche. One subject was excluded due to a uterine tumor; thus the final sample comprised 2,083 women.…”

Section: Methodsmentioning

confidence: 99%

Growth patterns in early childhood and the onset of menarche before age twelve

Martínez

Araújo²,

Horta

et al. 2010

Rev. Saúde Pública

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OBJECTIVE:To examine the relationship between growth patterns in early childhood and the onset of menarche before age 12. METHODS:The study included 2,083 women from a birth cohort study conducted in the city of Pelotas, Southern Brazil, starting in 1982. Anthropometric, behavioral, and pregnancy-related variables were collected through home interviews. Statistical analyses were performed using Pearson's chi-square and chi-square test for linear trends. A multivariable analysis was carried out using Poisson regression based on a hierarchical model. RESULTS:Mean age of menarche was 12.4 years old and the prevalence of menarche before age 12 was 24.3%. Higher weight-for-age, height-for-age, and weight-for-height z-scores at 19.4 and 43

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“…These children were subsequently visited at their homes on different occasions, and the methods used in these follow-ups have been described elsewhere ( 13 – 15 ) . In 1983, children born between January and April 1982 were visited, weighed and measured, and mothers answered a questionnaire that included information on health during the first year of life.…”

Section: Methodsmentioning

confidence: 99%

Association of family income with BMI from childhood to adult life: a birth cohort study

Gigante

Victora

Matijasevich

et al. 2012

Public Health Nutr.

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ObjectiveTo investigate the association of family income at birth with BMI among young adults who have been followed since birth.DesignA birth cohort study.SettingIn 1982, all children born in Pelotas, southern Brazil, were included in a perinatal survey and visited at ages 1, 2, 4, 15, 18–19 and 23 years.SubjectsCohort members (n 4297) were traced and interviewed in 2004–2005. In all follow-ups, participants were weighed and measured, and BMI and prevalence of obesity were calculated for each age. Family income was obtained in minimum wages in 1982 and as a continuous variable, in reais, in later follow-ups. Skin colour was self-reported in 2004–2005.ResultsMean BMI and prevalence of obesity differed between males and females. In males, a direct relationship was found throughout life and among females this relationship was modified by age. During childhood, BMI was higher among girls from higher income groups and this association was inversed at age 23 years. At this same age, mean BMI among black women was 1·3 kg/m2 higher than among white women, even after adjustment for current family income.ConclusionsThe findings show in men that the relationship between income and BMI is similar to that seen in less developed areas, whereas among adult women the relationship is similar to that observed in developed countries. In addition to the effect of socio-economic status, skin colour also has an influence on the BMI of adult women.

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The Pelotas birth cohort study, Rio Grande do Sul, Brazil, 1982-2001

Cited by 107 publications

References 20 publications

Maternal and child undernutrition: consequences for adult health and human capital

Maternal and child undernutrition: consequences for adult health and human capital

Growth patterns in early childhood and the onset of menarche before age twelve

Association of family income with BMI from childhood to adult life: a birth cohort study

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