On the rumors about the silent spring: review of the scientific evidence linking occupational and environmental pesticide exposure to endocrine disruption health effects

Cocco, Pierluigi

doi:10.1590/s0102-311x2002000200003

Cited by 112 publications

(50 citation statements)

References 138 publications

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“…Many epidemiological studies have suggested the possible role of pesticides in the occurrence of cancers (Blair et al, 1992;Dich et al, 1997;Acquavella et al, 1998), neurological diseases (Colosio et al, 2003) or reproductive disorders (Cocco, 2002). Exposure assessment represents a critical concern in these studies Zahm, 1990, 1993;Garcia et al, 2000;Hamey, 2001).…”

Section: Introductionmentioning

confidence: 99%

Pesticide contamination of workers in vineyards in France

Baldi¹,

Lebailly

Jean³

et al. 2005

J Expo Sci Environ Epidemiol

107

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In order to build tools to quantify exposure to pesticides of farmers included into epidemiological studies, we performed a field study in Bordeaux vineyards during the 2001 and 2002 treatment seasons to identify parameters related to external contamination of workers. In total, 37 treatment days were observed in tractor operators corresponding to 65 mixing operations, 71 spraying operations and 26 equipment cleaning. In all, four operators with backpack sprayers and seven re-entry workers were also monitored. We performed both detailed observations of treatment characteristics on the whole day and pesticide measurements of external contamination (dermal and inhalation) for each operation. The median dermal contamination was 40.5 mg of active ingredient per day for tractor operators, 68.8 mg for backpack sprayers and 1.3 mg for vineyard workers. Most of the contamination was observed on the hands (49% and 56.2% for mixing and spraying, respectively). The median contribution of respiratory route in the total contamination was 1.1%. A cleaning operation resulted in a 4.20 mg dermal contamination intermediate between a mixing (2.85 mg) and a spraying operation (6.13 mg). Farm owners experienced higher levels than workers and lower contaminations were observed in larger farms. The contamination increased with the number of spraying phases and when equipment cleaning was performed. Types of equipment influenced significantly the daily contamination, whereas personal protective equipment only resulted in a limited decrease of contamination.

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Section: Introductionmentioning

confidence: 99%

Pesticide contamination of workers in vineyards in France

Baldi¹,

Lebailly

Jean³

et al. 2005

J Expo Sci Environ Epidemiol

107

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“…We are still far from reaching a consensus on DDT use for controlling endemic diseases. There is considerable evidence on DDT's adverse effects on the environment and human health 77 . Still, malaria is a serious public health problem in developing countries like those of Sub-Saharan Africa, leading to extensive mortality 81 .…”

Section: Resultsmentioning

confidence: 99%

“…According to some authors, the malaria cases and deaths that could be averted by DDT far outweigh the health problems arising from its use 81,82,83 . Meanwhile, others have shown a clear concern over the future use of DDT (even if rationally applied) for vector control 34,77 .…”

Section: Resultsmentioning

confidence: 99%

“…The association between DDT and certain types of cancer (e.g., of the breasts, endometrium, ovaries, prostate, testes, and thyroid) and other endocrine effects is still a controversial issue 76 . Cocco 77 provides a review of experimental and epidemiological studies suggesting or refuting the associations, but which were modeled and designed differently.…”

Section: Reintroduction Of Ddt: Costs and Benefitsmentioning

confidence: 99%

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DDT reintroduction for malaria control: the cost-benefit debate for public health

2007

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DDT is a persistent insecticide that was widely used in the world from the 1940s until the 70s, when it was banned in the United States and other countries. Most of its toxic effects are not observed in the acute forms, but particularly after chronic exposure. These long-term issues include reproductive effects, varying according to the time of life in which the individuals were exposed. The aims of the current study were to review the principal toxicological effects of DDT on reproduction, stratifying by physiological periods of exposure, and based on the magnitude of these effects, to discuss the cost-benefit relationship of reintroducing DDT with the specifically defined vector control criteria.

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“…The most significant factors are familial inheritance, ultraviolet radiation, ionizing radiation, electromagnetic waves, chemical agents, viral infections, diet and interactions between children and environmental materials (Cocco, 2002;Cavdar, 1997;Buffer and Kyle, 1999). Early diagnosis has a significant importance in CC.…”

Section: Introductionmentioning

confidence: 99%

Spatial Distrubiton of Children Treated by Cancer in Zonguldak, Turkey

Topan¹,

Bayram²,

Özendi³

et al. 2016

Int. Arch. Photogramm. Remote Sens. Spatial Inf. Sci.

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ABSTRACT:This research is focused on the examination of child cancer cases in Zonguldak (Turkey) descriptively in epidemiological aspect thanks to GIS. Universe of the study is composed of 60 children between 0-19 years old, treated in Children Oncology Clinic of Health Application and Research Center in BEU. Whole universe was reached without selecting a sample in the study. Data were collected by using a form prepared by obtaining expert advice and they were applied to children and their parents at study dates. Results were expressed as percentages. Chi-Square test was used in intergroup comparisons, results were assessed within 95% confidence interval and p<0.05 was considered as statistically significant. Variables that were used in the study were assessed, recorded in prepared data collection form and distribution maps were produced. When disease diagnosis of the children participated in the study were evaluated, it was observed that 33.3% (n=20) were being treated for ALL, 13.3% (n=8) for Medullablastoma and 11.7% (n=7) for Hodgkin-nonHodgkin Lymphoma. It was detected that 31.7% (n=19) were in Ereğli, 31.7% (n=19) were in Central district and 18.3% (n=11) were in Çaycuma, when the places where children were living were evaluated. Statistically significant difference was found (p=0.016) comparing disease diagnosis with living place, and overall distribution map of the number of cancer cases was produced in this context. This is the first research subjecting the distribution of cancer cases for Zonguldak province.

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On the rumors about the silent spring: review of the scientific evidence linking occupational and environmental pesticide exposure to endocrine disruption health effects

Cited by 112 publications

References 138 publications

Pesticide contamination of workers in vineyards in France

Pesticide contamination of workers in vineyards in France

DDT reintroduction for malaria control: the cost-benefit debate for public health

Spatial Distrubiton of Children Treated by Cancer in Zonguldak, Turkey

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