Leishmaniose visceral no estado do Maranhão, Brasil: a evolução de uma epidemia

Costa, Jackson Maurício Lopes; Viana, Graça Maria C.; Saldanha, Ana Cristina R.; Nascimento, Maria D. S. B.; A, Alvim; Burattini, Marcelo Nascimento; Silva, Antonio R. da

doi:10.1590/s0102-311x1995000200016

Cited by 42 publications

(32 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Visceral leishmaniasis is endemic in Ilha de São Luis since the 1980s 5 , and an increased rate of migration of individuals from rural to urban areas and from other states has been observed during this period. These people settled in overcrowded and inadequate settlements constructed at the periphery of Ilha de São Luis (consisting of four municipalities), generally in recently inhabited and occupied areas characterized by deforestation and burning 21,22 . These conditions offer an excellent habitat for Lu.…”

Section: Discussionmentioning

confidence: 99%

Risk factors for Leishmania chagasi infection in an endemic area in Raposa, State of Maranhão, Brazil

Ponte

Souza

Cavalcante

et al. 2011

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

Introduction: Infection with Leishmania chagasi is the most common clinical presentation for visceral leishmaniaisis in endemic areas. The municipality of Raposa is an endemic area in State of Maranhão, Brazil, and have had registration cases of visceral leishmaniasis disease. For this reason, a cross-sectional study was conducted to evaluate the risk factors for infection with L. chagasi detected by Montenegro skin test. Methods: The sample comprised 96% of the inhabitants of the villages of Maresia, Pantoja, and Marisol located in the municipality of Raposa, corresponding to 1,359 subjects. Data were collected using a questionnaire. Univariate and multivariate logistic regression models were applied to evaluate the association between the variables studied and infection of L. chagasi. Results: The variables associated with infection upon nonadjusted analysis were a straw roof, mud walls, floors of beaten earth, presence of sand flies inside or outside of the dwelling, and bathing outdoors. Adjusted analysis showed that the presence of sand flies inside/outside the dwelling was a risk factor, and age younger than 10 years was a protective factor against asymptomatic infection. Conclusions: The results highlight the extent to which precarious living conditions of the population strengthen the epidemiological chain of visceral leishmaniasis.Keywords: Visceral leishmaniasis. Kalazar. Leishmania chagasi. Montenegro skin test. Risk factors. RESUMO Introdução:A infecção por Leishmania chagasi é a apresentação clínica mais comum de laishmaniose visceral em áreas endêmicas. O município de Raposa é área endêmica no Estado do Maranhão, tendo registrado casos da doença. Por isso, realizou-se um estudo transversal, com o objetivo de estudar os fatores de risco para infecção por L. chagasi detectada pelo teste intradérmico de Montenegro. Métodos: O estudo envolveu 96% dos moradores das localidades de Maresia, Pantoja e Marisol do município da Raposa, totalizando 1.359 indivíduos. O levantamento dos dados foi realizado utilizando um questionário. Para verificar a associação entre as variáveis estudadas e a infecção por L. chagasi, foram utilizados os modelos de regressão logística uni e multivariada. Resultados: Na análise não ajustada, as variáveis associadas à infecção foram: cobertura da casa de palha, paredes de taipa, piso de chão batido, a presença de flebotomíneos dentro ou fora do domicílio e o local do banho fora de casa. Na análise ajustada, a presença de flebotomíneos dentro ou fora do domicílio foi considerada fator de risco e a idade menor que 10 anos revelou-se como fator de proteção para a infecção assintomática. Conclusões: Evidenciou-se também, o quanto a precariedade das condições de vida da população contribui para o fortalecimento da cadeia epidemiológica da doença. Palavras

show abstract

Section: Discussionmentioning

confidence: 99%

Risk factors for Leishmania chagasi infection in an endemic area in Raposa, State of Maranhão, Brazil

Ponte

Souza

Cavalcante

et al. 2011

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

show abstract

“…Early diagnosis and treatment are required if morbidity and mortality from VL are to be reduced, as early-treated patients are clinically cured in 98% of cases, 34 while the fatality rate is near 95% in untreated cases 35 .…”

Section: Ethical Considerationsmentioning

confidence: 99%

Profile and geographic distribution of reported cases of visceral leishmaniasis in Campo Grande, State of Mato Grosso do Sul, Brazil, from 2002 to 2009

Brazuna

Silva

Brazuna³

et al. 2012

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

INTRODUCTION: This study sought to describe the profile and geographic distribution of reported cases of visceral leishmaniasis (VL) in the City of Campo Grande, State of Mato Grosso do Sul (MS), Brazil, from 2002 to 2009. METHODS: Human data were collected from the Brazilian National Information System for Notifiable Diseases. Canine cases and entomological data were obtained from the Information Service for Canine Visceral Leishmaniasis Control/Campo Grande, MS. RESULTS: A total of 951 records from 2002 to 2009 were investigated. The number of reported cases of VL in males was significantly higher (p < 0.0001) than that in females. The higher frequency observed among males was associated with age (p < 0.0001), which increased in individuals aged 40 years and older. The overall fatality rate was 7.4%. Entomological surveys conducted in 2006, 2007, and 2009 showed the insect vector Lutzomyia longipalpis to be present in all urban regions of the county. CONCLUSIONS: VL cases in humans and dogs, as well as in vectors, occurs in all urban regions of Campo Grande. Despite not observing tendencies of increase or reduction in the incidence of the disease due to aging, the major incidence in men is higher in those aged 40 years or above.

show abstract

“…12 Apesar de ser considerada endemia rural, a LV tem sido freqüentemente registrada em grandes centros urbanos. 3,6,7 Tal situação denota dificuldades enfrentadas no controle dessa doença e reflete a necessidade de novos estudos para avaliar a eficácia e efetividade das atuais medidas de controle, sobretudo, nas áreas prioritárias. 12 No Brasil, a abordagem atual do programa de controle da LV permite melhor definição das áreas de transmissão ou de risco e propõe ações de vigilância para os municípios considerados silenciosos.…”

Section: Introductionunclassified

Situação atual da epidemiologia da leishmaniose visceral em Pernambuco

Dantas‐Torres

2006

Rev. Saúde Pública

View full text Add to dashboard Cite

Current epidemiological status of visceral leishmaniasis in Northeastern Brazil RESUMOO objetivo do estudo foi descrever a situação epidemiológica atual da leishmaniose visceral no Estado de Pernambuco, Brasil. Para tanto, realizou-se revisão na literatura científica sobre a epidemiologia visceral em Pernambuco, por meio das buscas nas bases MEDLINE, SciELO e LILACS. Adicionalmente, foram consultados outros artigos relevantes que não foram localizados nas bases eletrônicas. Os 18 trabalhos selecionados para a revisão indicam que: a leishmaniose visceral possui ampla distribuição geográfica; os casos humanos estão freqüentemente associados à pressão antrópica sobre o meio ambiente; as crianças têm sido mais freqüentemente afetadas pela doença. Esses resultados mostraram a necessidade de mais estudos sobre os fatores de risco associados à incidência da doença no homem, o papel dos hospedeiros de Leishmania chagasi no ciclo zoonótico de transmissão e o comportamento do vetor nas diferentes regiões geográficas do Estado. DESCRITORES: Leishmaniose visceral, epidemiologia. Leishmaniose visceral, prevenção e controle. Revisão de literatura. ABSTRACTThe objective was to describe the current epidemiological status of visceral leishmaniasis in the State of Pernambuco, Northeastern Brazil. For that, a search for scientific production on epidemiology of visceral leishmaniasis in Pernambuco was carried out in electronic databases MEDLINE, SciELO and LILACS. Additionally, relevant papers that have not been retrieved from the searches were analyzed. The 18 studies selected for this review indicate that: visceral leishmaniasis is widely spread in Pernambuco; human cases are often associated to anthropic pressure on the environment; and children have been more frequently affected by the disease. These results showed the need for further studies on risk factors for visceral leishmaniasis in humans, the role of Leishmania chagasi hosts in the zoonotic transmission cycle, and the vector behavior in different geographical regions.

show abstract

Leishmaniose visceral no estado do Maranhão, Brasil: a evolução de uma epidemia

Cited by 42 publications

References 2 publications

Risk factors for Leishmania chagasi infection in an endemic area in Raposa, State of Maranhão, Brazil

Risk factors for Leishmania chagasi infection in an endemic area in Raposa, State of Maranhão, Brazil

Profile and geographic distribution of reported cases of visceral leishmaniasis in Campo Grande, State of Mato Grosso do Sul, Brazil, from 2002 to 2009

Situação atual da epidemiologia da leishmaniose visceral em Pernambuco

Contact Info

Product

Resources

About