Estudo comparativo de áreas endêmicas de filariose bancroftiana na região metropolitana do Recife, Brasil

Abstract

Comparative Studies on Endemic Areas of Bancroftian Filariasis in Greater Recife, Brazil. Cad. Saúde Públ., Rio de Janeiro, 10 (supplement 2): [301][302][303][304][305][306][307][308][309] 1994. Two districts in Recife (Santo Amaro and Campo Grande) and two districts in Olinda (Sapucaia and Salgadinho), were selected for a comparative study of bancroftian filariasis in Greater Recife. Selection parameters included similar socio-economic, demographic, and endemic levels of lymphatic filariasis. In the districts studied, streets were chosen randomly. These clusters consisted of 110 people each. A population sample was stratified by sex and age: 0-4, 5-9, 10-14, 15-19, 20-29, 30-39, 40-49, 50-59 and 60 years old and over. The parasitological data were obtained by measuring thick blood smears (60Fl), collected from 8:00 to 12:00 PM and processed and stained with hematoxylin. The data were described in tables, and logarithimic expression graphics were used to analyze parasitic densities. In general, Recife showed a prevalence of 13.5%, and Olinda 12.3%. Mean parasitic densities were 41 and 70 microfilariae/60Fl (mf/60Fl), respectively. Higher microfilaremic rates were observed in Recife for the 20-29-year age bracket and in Olinda in the 30-39-year bracket. The authors concluded that the disease has returned to former endemic levels, and the data described call for a reevaluation of control campaigns carried out by the Brazilian National Health Foundation, since the endemic has already reached serious proportions. Key words: Filariasis; Wuchereria bancrofti; Epidemiology INTRODUÇÃOA filariose corresponde a um grupo de doenças associadas a helmintos do filo Nematoda, superfamília Filarioidea. No Brasil encontram se as espécies Wuchereria, Onchocerca, e Mansonella, causando variado espectro clinicopatológico. A denominação "filariose linfática" está relacionada a três parasitos, Wuchereria bancrofti, Brugia timori, e Brugia malayi.Embora a filariose bancroftiana possa ocasionar considerável grau de morbidade, relacionado às formas agudas e crônicas da patologia, a mortalidade é quase nula.Segundo estimativa da Organização Mundial da Saúde (1992), três bilhões de pessoas vivem em países endêmicos, 75 milhões estão infectadas, entre as quais, 72 milhões por W. bancrofti. A distribuição geográfica da infecção/doença pela W. bancrofti atinge países como China, Indonésia, Índia e países africanos (WHO, 1992).A filariose teria chegado ao Brasil pelo tráfico de escravos; entretanto, os primeiros

Urban lymphatic filariasis

“…A study in 1991 (Maciel et al 1994) compared LF in two slum areas of Recife City to two in Olinda and found overall mf prevalence rates of 13.5 and 12.3 %, respectively. A survey in 2002 among 9,520 individuals (all ages) in Jaboatão dos Guararapes (Bonfim et al 2003) showed an mf prevalence of 2.2 % (range 0.0–5.2 % in 12 neighbourhoods).…”

Epidemiological study of bancroftian filariasis in Recife, Northeastern Brazil

“…The data obtained by Maciel et al (1994) for Greater Recife besides to validate the high levels of filariasis prevalence found by Morais (1982), showed that the disease had spread to areas where it had never been noticed before. The existing discrepancy in the data recorded by Ministério da of blood to be collected, and if the existence of recent control programs in the area, are taken in consideration.…”

Perfil protéico e reconhecimento antigênico de extratos de larvas infectantes (L3) de Wuchereria bancrofti

“…O percentual (11%)de microfilarêmicos encontrado neste trabalho confirma os dados de prevalência apresentados em inquéritos anteriores realizados no Município de Olinda 13 . De acordo com parâmetros da OMS, esses índices são considerados como de alta endemicidade 29 30 .…”