Doença renal medular cística em uma cadela Yorkshire Terrier: relato de caso

Abstract

RESUMOUma cadela da raça Yorkshire Terrier apresentou hematêmese, distensão abdominal, poliúria e polidipsia. Após o exame clínico do paciente, estabeleceu-se a suspeita clínica de nefropatia. Os resultados dos exames laboratoriais revelaram anemia normocítica normocrômica e concentrações séricas de uréia (306mg/dl) e de creatinina (3,6mg/dl) acima dos valores de referência. Ao ultra-som bidimensional observaram-se áreas císticas hipoecóicas e anecóicas, padrão renal hipercogênico e perda da relação corticomedular. À necropsia, a região medular apresentou grande quantidade de cistos pequenos em meio a tecido conjuntivo fibroso. A lesão tubulointersticial cortical foi a responsável pela insuficiência renal resultante. Firmou-se diagnóstico de nefrite tubulointersticial.Palavras-chave: cão, doença renal medular cística, nefrologia ABSTRACT A Yorkshire Terrier bitch presented hematemesis, abdominal distention, poliuria, and polidipsia. After clinical examination, it was established a clinical suspect of nephropathy. The complementary exams showed normochromic and normocytic anemia and serum concentrations of ureia (306mg/dl) and creatinine (3.6mg/dl) above the references values. At two-dimensional ultrasound hipoechoic and anechoic cystic areas were observed, as well as hiperechogenic renal pattern and corticomedullary ratio loss. At necropsy, the medullary region presented many small cysts in a fibrous connective tissue. Cortical tubulointesticial lesion was responsible to the resulting renal failure. It was established a tubulointersticial nephritis diagnosis.

Postmortem findings in collared peccaries raised in captivity in northeastern Brazil

“…Renal cystic disease is common in cats, dogs and humans (Beck & Lavelle 2001, Feliciano et al 2008) and has a congenital, hereditary or acquired origin, might cause chronic kidney disease due to compression and intratubular obstruction caused by inflammation and interstitial fibrosis (Feliciano et al 2008). We were unable to determine the cause of the polycystic kidney disease in this animal, but it is likely to have been an acquired case since the morphological characteristics of multifocal lymphoplasmacytic interstitial nephritis suggested pre-existing renal injury.…”