“…In horses, romifidine at doses varying from 0.4 to 1 mg/kg induces dose-dependent sedation. 9,10,11 Amitraz showed central effects of alpha-2 adrenoceptor agonist, inducing similar ataxia, intestinal stasis, behavioral, cardiovascular, muscular and diuretic effects. 12,13,14,15,16,17 These effects could provide an indication for the use of amitraz for sedation practices in veterinary medicine, and this might be particularly appealing in horses because of its low price and its potential analgesic and muscle relaxing effects.…”