Alterações morfológicas e funcionais dos rins de cães com insuficiência renal crônica

Camargo, M.H. Bueno de; Moraes, Julieta Rodini Engrácia de; Carvalho, Marileda Bonafim; Ferraro, Gabriella; Borges, Vanderci

doi:10.1590/s0102-09352006000500013

Cited by 4 publications

(2 citation statements)

References 4 publications

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“…In respect to the findings in the complete blood count, our study shows compatible results with the literature, according to which dogs with CKD have hemoglobin, hematocrit and red blood cells below the reference values for healthy animals (Bueno de Camargo et al 2006). The presence of lymphopenia is a finding in both humans (Allon et al 2003) and dogs (Bradea et al 2013) with CKD, which reinforces the fact that secondary infections are among the most common complications of the disease.…”

Section: Discussionsupporting

confidence: 90%

Randomized controlled clinical trial of ketoanalogues supplementation in dogs with chronic kidney disease

et al. 2018

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RESUMO.-[Estudo clínico randomizado controlado da suplementação de cetoanálogos em cães com doença renal crônica.] O objetivo foi de verificar a eficácia da suplementação com cetoanálogos em cães com Doença Renal Crônica (DRC) grau 3. Um ensaio clínico controlado e randomizado foi realizado com 20 cães com DRC grau 3. Os animais foram divididos em 4 grupos: grupo 1 (controle): terapia convencional (TC) para DRC; grupo 2: TC e 60mg/kg, VO, q48h de cetoanálogoa; grupo 3: TC e 60mg/kg, VO, q24h de cetoanálogoa; e grupo 4, TC e 120mg/kg, VO, q12h de cetoanálogoa. Todos os cães receberam ração renal para cães. Os animais foram avaliados no início da terapia e após 15 e 30 dias. Hemograma completo, ureia, creatinina, fósforo, cálcio, potássio e sódio séricos e a razão proteína creatinina (RPC) urinária foram analisados. Foi verificado que o uso dos cetoanálogos em cães com DRC grau 3 durante 30 dias não mostrou eficácia, em nenhuma das dosagens utilizadas, em melhorar os sinais clínicos e sintomatologia da doença, os valores do hemograma e ureia e creatinina séricos, normalizar eletrólitos e reduzir RPC. Concluiu-se que o uso de cetoanálogos

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Section: Discussionsupporting

confidence: 90%

Randomized controlled clinical trial of ketoanalogues supplementation in dogs with chronic kidney disease

et al. 2018

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“…Nefrite túbulo-intersticial, atribuída à leptospirose pelas características morfológicas, foi observada em 35,8% dos casos de ME/EUT anteriormente mencionados. Esta lesão é descrita em cães com sorologia positiva para Leptospira spp., e os sorovares mais frequentes em diferentes populações caninas são icterohaemorrhagiae (Bueno de Camargo et al 2006) e canicola (Ortega-Pacheco et al 2008). Outros sorovares também descritos em cães incluem pommona (Birnbaum et al 1998, Cowgill & Elliott 2008, bratislava (Cowgill & Elliott 2008) e grippotyphosa (Birnbaum et al 1998;Wild et al 2002, Cowgill & Elliott 2008.…”

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Lesões do sistema urinário em 1.063 cães

et al. 2012

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Pesq. Vet. Bras. 32(8) The aim of this study was to determine the prevalence, epidemiology, clinical signiϐi-cance, and possible associated causes of the urinary system lesions in dogs necropsied between January 1999 and December 2010 at the Laboratório de Patologia Veterinária of the Universidade Federal de Santa Maria (LPV-UFSM). To accomplish this, the necropsy reports were analyzed retrospectively. In this time frame, 3,189 dogs were necropsied and about 30% had lesions in the urinary system. In most of the dogs (79.1%), lesions were single and in about 21% they were multiple, totalizing 1,373 lesions. Out of them, 1,014 (73.8%) were observed in the kidney and 359 (26.2%) were in the lower urinary tract (LUT). One third of the lesions in the urinary system were causes of spontaneous death or reason for euthanasia (SD/EUTH) of the affected dogs. The other two third of the lesions were considered incidental ϐindings. The main renal lesions diagnosed, in descending order of prevalence, were: tubulointerstitial nephritis, infarct, granulomatous nephritis (parasitary), glomerulonephritis, metastatic/multicentric neoplasms, pyelonephritis/pyelitis, and hydronephrosis. The main LUT lesions, in descending order of prevalence, were: cystitis, presence of viral inclusions bodies (morbillivirus), urolithiasis, urinary bladder dilatation, urinary bladder rupture (with uroperitoneum), and metastatic/multicentric neoplasms. Epidemiological aspects such as gender, breed, and age of affected dogs had expressive variations according to the type of lesion diagnosed. Uremia was observed in a signiϐicant number of cases of SD/EUTH and was mostly due to renal lesions.INDEX TERMS: Lesions of the urinary tract, diseases of dogs, pathology.

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Applicability of B-mode ultrasonography, ARFI elastography and contrast-enhanced ultrasound in the evaluation of chronic kidney disease in dogs

et al. 2021

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The objective of this study was to verify the applicability of B-mode ultrasonography, ARFI elastography and CEUS in the diagnosis of chronic kidney disease and its Stages in dogs. 24 healthy dogs and 28 with CKD were included. In B-mode, the echogenicity, echotexture and cortico-medullary ratio of the kidneys were verified. By elastography, the shear-wave velocity of the cortical (SWVcort) and medullary (SWVmed) regions were determined and tissue deformity was evaluated. Wash-in, wash-out and peak enhancement (TPic) of the contrast in the renal parenchyma were calculated and homogeneity, presence of filling gaps and distinction of filling phases were evaluated by CEUS. Changes in echogenicity, echotexture and cortico-medullary ratio were observed only in sick patients. There was an increase in SWVcort in CKD, with a cutoff point >2.91m/s. Healthy kidneys were non-deformable and 25% had changes in gray scales. There was an increase in wash-in and TPic, changes in filling characteristics, filling failures and difficulty in distinguishing between the Stages in CEUS in CKD. It was found that dogs with CKD 2, 3 and 4 had greater SWVcort and wash-in values than CKD 1. Elastographic and CEUS changes were observed in dogs with CKD, demonstrating the applicability of ultrasonographic techniques in their diagnosis.

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Alterações morfológicas e funcionais dos rins de cães com insuficiência renal crônica

Cited by 4 publications

References 4 publications

Randomized controlled clinical trial of ketoanalogues supplementation in dogs with chronic kidney disease

Randomized controlled clinical trial of ketoanalogues supplementation in dogs with chronic kidney disease

Lesões do sistema urinário em 1.063 cães

Applicability of B-mode ultrasonography, ARFI elastography and contrast-enhanced ultrasound in the evaluation of chronic kidney disease in dogs

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