Tumor carcinóide de reto

Colonic carcinoid tumors: a clinicopathologic study of 23 patients from a single institution

“…Colonic carcinoid tumors are usually nonfunctioning, but occasionally serotonin-producing tumors have been observed in the colon (7,24) . Neuron-specific enolase and serotonin are the most frequently noted immunohistochemical positive stains in carcinoid tumors of the colon (22) . In the immunohistochemical study performed on 15 (65.2%) tumors in this series, all disclosed chromogranin and/or neuron-specific enolase positive staining.…”

“…Carcinoid tumors (well-differentiated endocrine tumors), a heterogeneous group of rare neoplasms with neuroendocrine features found in the gastrointestinal tract, the ovaries, and the lungs, are the most intriguing and most commonly encountered tumors of the diverse neuroendocrine tumor group (12,14,18,20,21,22) . They may produce a variety of hormones and have a variable histological pattern and biologic behavior (20,22,30,31) .…”

Rectal carcinoid tumor: diagnosis and management

“…Although potentially metastatic, carcinoid syndrome is rare. 2 Therefore, although rectal carcinoids present relatively indolent behavior, they are malignant and can metastasize, as postulated by the American Joint Committee on Cancer. 1 Despite the various reclassifications of the World Health Organization, the term "carcinoid" is still used as a synonym for "well differentiated neuroendocrine tumor" and the term "malignant carcinoid" is used as a synonym for "well differentiated neuroendocrine carcinoma."…”

“…1 The term Karzinoide was used by Oberndorfer in 1907 to describe ileal tumors that presented a more benign behavior than typical adenocarcinomas. 2 Neuroendocrine tumors grow from Kulchitsky or chromaffin cells, which cover the epithelium of the respiratory and gastrointestinal tract. They originate in the crypts of Lieberkühn.…”

“…They originate in the crypts of Lieberkühn. 2 These are rare neoplasms that account for only 0.49% of all malignant tumors. 3 Despite being relatively uncommon when compared with rectal adenocarcinoma, there is evidence that the incidence of rectal carcinoid tumors is increasing, perhaps related to increased diagnosis secondary to greater access to endoscopy.…”