Investigation of the effects of peppermint (Mentha piperita) on the biochemical and anthropometric profile of university students

Barbalho, Sandra Maria; Farinazzi-Machado, Flávia Maria Vasques; Oshiiwa, Marie; Abreu, Marcio Costa; Guiger, Ellen Landgraf; Tomazela, Paschoal; Goulart, Ricardo de Álvares

doi:10.1590/s0101-20612011000300006

Cited by 16 publications

(10 citation statements)

References 33 publications

(35 reference statements)

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“…1 Several studies have demonstrated that peppermint extracts decrease glucose, total cholesterol, triacylglycerols, very lowdensity lipoprotein (VLDL), and low-density lipoprotein (LDL) levels, thus decreasing the atherogenic index in diabetic rats. 4,5 These health benefits can be enhanced using preharvest strategies to increase bioactive compounds in the peppermint leaves. In a wide variety of plant species, deficit irrigation has been shown to enhance the synthesis of several phytochemicals, including phenolic acids, flavonoids, and tannins, as a response to stress constraints.…”

Section: ■ Introductionmentioning

confidence: 99%

Metabolite Profile, Antioxidant Capacity, and Inhibition of Digestive Enzymes in Infusions of Peppermint (Mentha piperita) Grown under Drought Stress

Figueroa-Pérez

Rocha‐Guzmán

Pérez‐Ramírez

et al. 2014

J. Agric. Food Chem.

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Peppermint (Mentha piperita) infusions represent an important source of antioxidants, which can be enhanced by inducing abiotic stress in plants. The aim of this study was to evaluate the effect of drought stress on peppermint cultivation as well as the metabolite profile, antioxidant capacity, and inhibition of digestive enzymes of resulting infusions. At 45 days after planting, irrigation was suppressed until 85 (control), 65, 35, 24, and 12% soil moisture (SM) was reached. The results showed that 35, 24, and 12% SM decreased fresh (20%) and dry (5%) weight. The 35 and 24% SM treatments significantly increased total phenolic and flavonoid contents as well as antioxidant capacity. Coumaric acid, quercetin, luteolin, and naringenin were detected only in some drought treatments; however, in these infusions, fewer amino acids and unsaturated fatty acids were identified. The 24 and 12% SM treatments slightly improved inhibition of pancreatic lipase and α-amylase activity. Therefore, induction of moderate water stress in peppermint is recommended to enhance its biological properties.

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Section: ■ Introductionmentioning

confidence: 99%

Metabolite Profile, Antioxidant Capacity, and Inhibition of Digestive Enzymes in Infusions of Peppermint (Mentha piperita) Grown under Drought Stress

Figueroa-Pérez

Rocha‐Guzmán

Pérez‐Ramírez

et al. 2014

J. Agric. Food Chem.

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“…In vitro studies showed that peppermint essential oil and menthol acted as smooth muscle relaxants via blocking Ca 2+ influx through L-type Ca 2+ channels [ 77 , 78 ]. Also peppermint juice led to reduction in total cholesterol levels, triglycerides and could increase HDL levels in the blood of university students [ 79 ] ( Figure 1 ).…”

Section: Properties Of the Mentha Genusmentioning

confidence: 99%

The Wonderful Activities of the Genus Mentha: Not Only Antioxidant Properties

et al. 2021

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: Medicinal plants and their derived compounds have drawn the attention of researchers due to their considerable impact on human health. Among medicinal plants, mint (Mentha species) exhibits multiple health beneficial properties, such as prevention from cancer development and anti-obesity, antimicrobial, anti-inflammatory, anti-diabetic, and cardioprotective effects, as a result of its antioxidant potential, combined with low toxicity and high efficacy. Mentha species are widely used in savory dishes, food, beverages, and confectionary products. Phytochemicals derived from mint also showed anticancer activity against different types of human cancers such as cervix, lung, breast and many others. Mint essential oils show a great cytotoxicity potential, by modulating MAPK and PI3k/Akt pathways; they also induce apoptosis, suppress invasion and migration potential of cancer cells lines along with cell cycle arrest, upregulation of Bax and p53 genes, modulation of TNF, IL-6, IFN-γ, IL-8, and induction of senescence phenotype. Essential oils from mint have also been found to exert antibacterial activities against Bacillus subtilis, Streptococcus aureus, Pseudomonas aeruginosa, and many others. The current review highlights the antimicrobial role of mint-derived compounds and essential oils with a special emphasis on anticancer activities, clinical data and adverse effects displayed by such versatile plants.

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“…Several findings have depicted the potential antidiabetic capability of genus Mentha . M. piperita could alleviate hyperglycemia induced by streptozotocin–nicotinamide-induced type 2 diabetes in rats, and cause a reduction of glycemia in human [ 9 , 10 ]. However, no report has referred to the active compounds of Mentha responsible for its antidiabetic capability.…”

Section: Introductionmentioning

confidence: 99%

Chemical Constituents from Mentha haplocalyx Briq. (Mentha canadensis L.) and Their α-Glucosidase Inhibitory Activities

Geng

Huang

et al. 2019

Nat. Prod. Bioprospect.

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Mentha haplocalyx ( Mentha canadensis ) is widely used as a medicinal plant in traditional Chinese medicine, and the extracts of its aerial parts are found to significantly inhibit the activity of α-glucosidase with an IC 50 value of 21.0 μg/mL. Bioactivity-guided isolation of the extracts afforded two new compounds ( 1 and 2 ), together with 23 known ones ( 3 – 25 ). Their structures were established by extensive spectroscopic analyses (1D and 2D NMR, MS, IR and UV). Compounds 1 – 17 and 21 – 25 were evaluated for their α-glucosidase inhibitory activities. Compound 11 was the most active ones with an IC 50 values of 83.4 μM. These results verify the α-glucosidase inhibitory activity of M. haplocalyx ( M. canadensis ) and specify its active compounds for the first time. Graphical Abstract Electronic supplementary material The online version of this article (10.1007/s13659-019-0207-0) contains supplementary material, which is available to authorized users.

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Investigation of the effects of peppermint (Mentha piperita) on the biochemical and anthropometric profile of university students

Cited by 16 publications

References 33 publications

Metabolite Profile, Antioxidant Capacity, and Inhibition of Digestive Enzymes in Infusions of Peppermint (Mentha piperita) Grown under Drought Stress

Metabolite Profile, Antioxidant Capacity, and Inhibition of Digestive Enzymes in Infusions of Peppermint (Mentha piperita) Grown under Drought Stress

The Wonderful Activities of the Genus Mentha: Not Only Antioxidant Properties

Chemical Constituents from Mentha haplocalyx Briq. (Mentha canadensis L.) and Their α-Glucosidase Inhibitory Activities

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