Effects of chronic treadmill training on body mass gain and visceral fat accumulation in overfed rats

Abstract

This study evaluated the effects of chronic treadmill training on body mass gain and visceral fat accumulation in overfed rats. Overfeeding was induced by reducing the litter size to 3 male pups per mother during the suckling period. The litter size of control rats was adjusted to 10 male pups per mother. Seven weeks after birth overfed and normally fed rats were selected and assigned to a sedentary protocol or to a low-intensity treadmill training protocol (60 min, 5 times/week, for 9 weeks). Four groups (overfed sedentary, N = 23; normally fed sedentary, N = 32; overfed exercised, N = 18, and normally fed exercised, N = 18) were evaluated at 18 weeks. Data are reported as means ± SEM. Initial body weight was similar in control and overfed rats [8.0 ± 0.2 g (N = 42) vs 8.0 ± 0.1 g (N = 50); P > 0.05] and body weight gain during the suckling period was higher in the overfed rats (30.6 ± 0.9 vs 23.1 ± 0.3 g; P < 0.05). Exercise attenuated the body weight gain of overfed compared to sedentary rats (505 ± 14 vs 537 ± 12 g; P < 0.05). The sedentary overfed rats showed higher visceral fat weight compared to normally fed animals (31.22 ± 2.08 vs 21.94 ± 1.76 g; P < 0.05). Exercise reduced visceral fat by 36.5% in normally fed rats and by 35.7% in overfed rats. Exercise attenuated obesity in overfed rats and induced an important reduction of visceral fat.

Effects of running wheel training on adult obese rats programmed by maternal prolactin inhibition

“…Similar modifications in fat mass were described previously (Dantas et al 2010) in animals exposed to overfeeding after treadmill training for 60 min/day, 5 days a week. Scomparin et al (2006) reported that mice that were previously treated with monosodium glutamate (MSG) during the neonatal period had lower levels of visceral fat after shorter sessions of swimming training (15 min/day, 3 days a week), suggesting that the beneficial effects of chronic exercise could be achieved with lower training parameters.…”

Moderate exercise training does not prevent the reduction in myocardial L-type Ca2+ channels protein expression at obese rats

“…On the other hand, caloric expenditure during ET and the positive chronic influence of an exercise training protocol on body composition, mainly, by decreasing of adipose content are well established. Some authors have shown that aerobic training was effective to decrease adipose tissue area and total adiposity in rats (Friedman, 2009;Haram et al 2009;Dantas et al 2010;Machado et al 2014;Rinaldi et al 2014). From the period that ET was include on our experimental protocol, the caloric value of high-fat diet was nullified, whereas, ObET rats showed lipid profile similar to C and ET rats at the end of experiment.…”

“…Furthermore, different intensities of ET are useful tool to promote cardioprotection (Dantas et al. ; Paulino et al. ; Caponi et al.…”

“…Thus, studies show that moderate exercise training (MET) is appropriated to this specific group (Paulino et al 2010;Caponi et al 2012;Rinaldi et al 2014). Furthermore, different intensities of ET are useful tool to promote cardioprotection (Dantas et al 2010;Paulino et al 2010;Caponi et al 2012;Rinaldi et al 2014).…”

[ARTIGO RETRATADO] Exercício e suas interações com vários aspectos da vida do homem e dos animais

“…Mild physical training on the treadmill during pregnancy did not interfere with bone development and growth of the offspring. Dantas et al 32 evaluated the effects of chronic treadmill training on body mass gain and visceral fat accumulation in overfed newly born rats. Overfeeding was induced by reducing the litter size to 3 male pups per mother during suckling, while control litter size was adjusted to 10 male pups per mother.…”