Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease

Sanchez, Fernanda Figueirôa; Faganello, Márcia Maria; Tanni, Suzana Erico; Lucheta, Paulo Adolfo; Padovani, Carlos Roberto; Godoy, Irma

doi:10.1590/s0100-879x2008005000043

Cited by 22 publications

(15 citation statements)

References 26 publications

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“…The impact of variables such as FEV 1 on quality of life, as assessed using the SGRQ, has not been demonstrated in other studies that used multivariate analysis. (6,8) We observed that 57.1% of the patients in the present study were classified as having severe or extremely severe COPD, and this fact might have affected the results. This correlation between severity of COPD and quality of life has been demonstrated in the literature.…”

Section: Resultsmentioning

confidence: 67%

“…Although some studies showed a correlation between respiratory function parameters and quality of life, (3)(4)(5) others found no such correlation. (6)(7)(8) The discrepancies found in the literature can be explained by the methods used in the studies. Some studies assessed subgroups of patients with more severe disease, (3,4) others studied the influence of several disease-related parameters, such as body mass index (9) or age, (10) and some used dyspnea scales in the assessments.…”

Section: Introductionmentioning

confidence: 99%

“…Some studies assessed subgroups of patients with more severe disease, (3,4) others studied the influence of several disease-related parameters, such as body mass index (9) or age, (10) and some used dyspnea scales in the assessments. (6)(7)(8) Another important factor to be explored is the choice of the instrument used to assess quality of life. Few studies have assessed the impact of respiratory function parameters on the quality of life of COPD patients by simultaneously using the Saint George's Respiratory Questionnaire (SGRQ) and the Medical Outcomes 36-item Short-Form Survey (SF-36), through its physical component summary (PCS) and its mental component summary (MCS).…”

Section: Introductionmentioning

confidence: 99%

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Influência dos parâmetros funcionais respiratórios na qualidade de vida de pacientes com DPOC

et al. 2009

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Objective: To determine the quality of life of COPD patients by using the Medical Outcomes 36-item Short-Form Survey (SF-36) and the Saint George's Respiratory Questionnaire (SGRQ), correlating the scores with respiratory function parameters. Methods: This was a cross-sectional study involving 42 COPD patients. We used the SGRQ (a specific questionnaire) and the SF-36 (a general questionnaire), together with their component summaries, in order to determine the quality of life of these patients. The functional profile was assessed by means of spirometry, arterial blood gas analysis and the six-minute walk test. Results: Of the 42 patients, 30 (71.4%) were male and 12 (28.6%) were female. The mean age of the patients was 65.4 ± 8.0 years. The mean physical component summary and mean mental component summary scores were 37.05 ± 11.19 and 45.61 ± 15.65, respectively. The physical component summary correlated significantly with FEV 1 in L/s (r = 0.38; p = 0.012). There was a correlation between the SGRQ total score and FEV 1 (r = −0.50; p < 0.01). The SGRQ activity domain showed negative correlations with all respiratory function parameters. The multiple regression analysis showed that only FEV 1 correlated significantly with the SGRQ total score, as well as with the activity domain score (r= −0.32; p = 0.04 and r = −0.34; p = 0.03, respectively). Conclusions: In COPD patients, a decline in FEV 1 is associated with poorer quality of life, as evaluated using the SGRQ. The objective of the present study was to determine how respiratory function parameters-as assessed by spirometry, arterial blood gas analysis and the six-minute walk test (6MWT)-correlate with the quality of life of COPD patients by using the SGRQ (a specific questionnaire), as well as the SF-36 (a general questionnaire) and its component summaries (PCS and MCS).

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Section: Resultsmentioning

confidence: 67%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Influência dos parâmetros funcionais respiratórios na qualidade de vida de pacientes com DPOC

et al. 2009

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“…Further, prior research has often grouped older and younger workers together,4 so that limiting the analyses to those aged 40–64 years helps homogenize the sample and isolates those in their peak earning years. This focus is also helpful in that most HRQoL studies have ignored those under the age of 65 years with COPD 4–7,19,20…”

Section: Discussionmentioning

confidence: 99%

The burden of chronic obstructive pulmonary disease among employed adults

DiBonaventura¹,

Paulose-Ram²,

Su³

et al. 2012

COPD

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ObjectiveTo examine quality of life, work productivity, and health care resource use among employed adults ages 40–64 years with chronic obstructive pulmonary disease (COPD) in the United States.MethodsData from the 2009 National Health and Wellness Survey were used. All employed adults ages 40–64 years with or without a self-reported diagnosis of COPD were included in the study. Impact on quality of life (using the mental and physical component summary scores and health utilities from the Short Form-12v2), work productivity and activity impairment (using the Work Productivity and Activity Impairment questionnaire), and resource use were analyzed using regression modeling.ResultsThere were 1112 employed adults with COPD versus 18,912 employed adults without COPD. After adjusting for demographics and patient characteristics, adults with COPD reported significantly lower mean levels of mental component summary (46.8 vs 48.5), physical component summary (45.6 vs 49.2), and health utilities (0.71 vs 0.75) than adults without COPD. Workers with COPD reported significantly greater presenteeism (18.9% vs 14.3%), overall work impairment (20.5% vs 16.3%), and impairment in daily activities (23.5% vs 17.9%) than adults without COPD. Employed adults with COPD also reported more mean emergency room visits (0.21 vs 0.12) and more mean hospitalizations (0.10 vs 0.06) in the previous 6 months than employed adults without COPD. All of the above differences were significant at two-sided P < 0.05.ConclusionAfter adjusting for various confounders, employed adults with COPD reported significantly lower quality of life and work productivity, and increased health care resource utilization than employed adults without COPD. These results highlight the substantial impact and burden of COPD in the United States workforce.

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“…KOAH'l hastalarda bireyi günlük ya am aktiviteleri s ras nda k s tlayan ve ya am kalitesi ile yak ndan ilikili olan en önemli semptomun dispne oldu u kabul edilmektedir. OUAS'l hastalarda ise alg lanan uyku hali ve genel yorgunluk düzeyi bireyi günlük ya am aktiviteleri s ras nda k s tlayan en önemli semptomlar olarak belirtilmektedir [21][22][23]. Bu çal malarla uyumlu olarak OUAS'l hastalarda 6DYM ile 6DYT sonras nda alg lanan dispne ve bacak yorgunlu u iddetlerinin korele oldu unu sapta- Veriler, aksi belirtilmedikçe ortalama±standart sapma (SS) olarak gösterilmi tir * p 0.05, VK : vücut kitle indeksi; FEV 1 = birinci saniyedeki zorlu ekspiratuvar volüm, FVC= zorlu vital kapasite d k. Bu sonuç, KOAH'l hastalardan farkl olarak OUAS'l hastalarda egzersiz kapasitesindeki k s tlanman n hastan n egzersiz sonras nda alg lad semptomlarla daha fazla ili kide oldu unu dü ündürmektedir.…”

Section: Tarti Maunclassified