Intoxicação espontânea por antibióticos ionóforos em ovinos no Rio Grande do Sul

Abstract

Um surto de intoxicação espontânea por antibióticos ionóforos em ovinos da região Central do Rio Grande do Sul é descrito. Os 16 ovinos afetados estavam em campo nativo e ingeriram acidentalmente um aditivo alimentar para frangos contendo 250g/kg de narasina. Os sinais clínicos consistiam de fraqueza, incoordenação, dispnéia, secreção nasal, decúbito e morte em poucas horas. Um ovino apresentou urina escura. Macroscopicamente havia ascite, hidrotórax, edema pulmonar e palidez hepática. Discreto grau de degeneração muscular na musculatura esquelética dos membros pélvicos e torácicos foi observado histologicamente. O diagnóstico de intoxicação por narasina foi realizado com base no histórico (ingestão de aditivo alimentar contendo narasina) e nos achados clinico-patológicos.

Spontaneous poisoning by Ateleia glazioviana (leg. Papilionoideae) in sheep and goats in the West region of Santa Catarina

“…(Bandarra et al 2005, Vasconcelos et al 2008, Schons et al 2011, Soares et al 2011, Becker et al 2013. In general, animals poisoned by these plants do not manifest previous clinical changes or macroscopic lesions, which differs from poisoning by A. glazioviana Outbreaks of poisoning by ionophore antibiotics have been described in sheep (Bastianello et al 1995, Wouters et al 1997, França et al 2009, Rissi & Barros 2010 and cause a clinical and pathological conditions similar to A. glazioviana poisoning. However, sheep poisoned by ionophores have some distinct signs and injuries, such as diarrhea and signs of muscle weakness.…”

Megaesophagus in sheep and goats

“…Thus, infection by blue tongue virus, a disease that causes megaesophagus, skeletal musculature necrosis and infiltration by inflammatory cells (ANTONIASSI et al, 2010), was considered among the presumptive diagnoses. Other causes for muscle segmental necrosis are intoxication by ionophore antibiotics and by plants such as Senna occidentalis and Senna obtusifolia (RISSI, 2010;TOKARNIA et al, 2012), in addition to selenium and vitamin E deficiency, already diagnosed in the region (AMORIM et al, 2005). However, the negative results for blue tongue in sheep 1 and goat 2 and the absence of Senna spp.…”

“…in the pasture exclude both possibilities. There was no history of supplementation with ionophore antibiotics and the epidemiologic aspects and esophageal lesions were not consistent with Se and vitamin E deficiency, since such illness affects mainly rapid growing young animals and there is no record of megaesophagus in the reported clinical picture (AMORIM et al, 2005;RISSI, 2010). One of the most distinguished aspects in those cases is the fact that, despite the most obvious clinical signs being a result of the megaesophagus, all animals showed segmental muscle necrosis in several muscles.…”

Accidental monensin poisoning in buffaloes in Bahia, Brazil

“…Cases of poisoning by IAs have been described in several species, such as horses (Pavarini et al 2011, Sousa et al 2019, cattle (Gava et al 1997, Brito et al 2020, sheep (Souza et al 2008, Rissi & Barros 2010, buffaloes (Rozza et al 2006, Bence et al 2018, Garcia et al 2020, goats (Deljou et al 2014), pigs (Miskimins & Neiger 1996), canines (Segev et al 2004), rabbits (Peixoto et al 2009), chinchillas (Lucena et al 2012), camels (Mousa & El-Hamamsy 2013), collared peccaries (Ribeiro & Santos 2016), and ostriches (Pavarini et al 2011). Poisoning occurs due to accidental consumption of food with IAs, feed contamination, or incorrect use due to an error in either the calculation or the homogenization of the premix to the feed (França et al 2009), by the concomitant use of drugs that potentiate the effects of IAs (Basaraba et al 1999), or when inadvertently supplied to non-target species (Pavarini et al 2011).…”