Câncer de mama em mulheres no Maranhão: estudo de sobrevida no Centro de Assistência de Alta Complexidade em Oncologia (CACON) em São Luís - MA (1998-2004)

Silva, Dulcelena Ferreira

doi:10.1590/s0100-72032006000600009

Rev. Bras. Ginecol. Obstet.

2006

DOI: 10.1590/s0100-72032006000600009

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Câncer de mama em mulheres no Maranhão: estudo de sobrevida no Centro de Assistência de Alta Complexidade em Oncologia (CACON) em São Luís - MA (1998-2004)

Dulcelena Ferreira Silva¹

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Family history in breast cancer in São Luís, Maranhão, Brazil

Ribeiro

Silva

Filho³

et al. 2016

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BackgroundFamilial cancer includes some types of cancer aggregation without a well-defined inheritance pattern. Cancer genetics is an essential component of clinical practice in oncology. In Brazil, breast cancer is the leading cause of death in women. In Maranhão, studies on genetic predisposition are necessary to investigate the incidence and mortality rates. The aim of this study was to investigate familial cancer among relatives of women who died of breast cancer in São Luís, Brazil, constructing a pedigree to identify families with a hereditary predisposition, an important step in the early diagnosis of malignant tumors.MethodsThe city of São Luís is located on the Island of Maranhão, northeastern Brazil, with a population of 997,098 inhabitants mainly comprising blacks and mulattoes, including descendants of runaway slaves from the Amazon region itself. Data for pedigree construction were obtained from the records of 54 patients seen at the Aldenora Bello Institute of Oncology, São Luís, between 2000 and 2007, as well as by interview with relatives of the patients.ResultsThe mean patient age at diagnosis was 39.5 years. Most women were mulattoes (36/54, 66.6 %). A history of cancer was observed in 18 families, with 16 families possessing cases of cancer among first-degree relatives and five among second-degree relatives.ConclusionA concentration of cancer cases was found in families of patients diagnosed until the age of 40, a finding demonstrating the importance of a family history prior to genetic counseling.

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Family history in breast cancer in São Luís, Maranhão, Brazil

Ribeiro

Silva

Filho³

et al. 2016

BMC Res Notes

Self Cite

View full text Add to dashboard Cite

show abstract

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Câncer de mama em mulheres no Maranhão: estudo de sobrevida no Centro de Assistência de Alta Complexidade em Oncologia (CACON) em São Luís - MA (1998-2004)

Cited by 1 publication

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Family history in breast cancer in São Luís, Maranhão, Brazil

Family history in breast cancer in São Luís, Maranhão, Brazil

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