Incidência de infecção do sítio cirúrgico com o preparo pré-operatório utilizando iodopolividona 10% hidroalcoólica e clorexidina alcoólica 0,5%

Al, Rodrigues; L, Simões Mde

doi:10.1590/s0100-69912013000600004

Cited by 33 publications

(21 citation statements)

References 20 publications

(25 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Antiseptics were used in different types (e.g., povidone iodine, metronidazole, and chlorhexidine), different forms (e.g., solutions or wipes), and different methods; such as vaginal cleansing or skin scrub. [10][11][12][13] A systematic review was proven that vaginal cleansing using chlorhexidine is fairly safe, not expensive, and easy to be used. [14] The investigators of that review suggested more well-designed randomized clinical trials for evaluating that safe simple valuable procedure.…”

Section: Introductionmentioning

confidence: 99%

Effect of preoperative vaginal cleansing using chlorhexidine antiseptic on post cesarean section infectious morbidity

Marzouk

Emarah

Zaitoun

2019

CNS

View full text Add to dashboard Cite

Objective: This study aims to assess effect of preoperative vaginal cleansing using chlorhexidine antiseptic on post cesarean section infectious morbidity. Methods: A randomized controlled trial was conducted on a random sample of 178 singleton term pregnant woman assigned for elective cesarean section. A simple random sample was recruited from the operating room of Obstetrics and Gynecology department, Zagazig University Hospitals-Egypt. Participants were randomly assigned either to conventional care group or study group. The conventional care group was exposed to the usual abdominal scrub with Povidone-iodine solution; while the study group subjected to vaginal cleansing using chlorhexidine antiseptic solution in addition to conventional preoperative care. Data were collected using an assessment sheet for demographic and clinical data and checklist for study outcomes. Results: Post intervention, assessment of the incisional wound revealed lower overall post cesarean section infectious morbidity rate among study group compared to those received conventional care (9.0% vs. 20.2% respectively; χ 2 = 4.50, p = .034). Endometritis rate was significantly lower among the study group subjects equated to those of the conventional care group (2.2% vs. 10.1% respectively; χ 2 = 4.75, p = .029), meanwhile febrile morbidity and surgical site infection rates showed non-significant reduction in favor to the study group subjects (p = .469 and .700 respectively). Conclusions: Preoperative vaginal cleansing using chlorhexidine was an effective practice for reducing post cesarean infection; where overall post cesarean infectious morbidity rate was lower among postpartum mothers subjected to vaginal cleansing compared to those exposed to conventional care alone; supporting the study hypothesis.

show abstract

Section: Introductionmentioning

confidence: 99%

Effect of preoperative vaginal cleansing using chlorhexidine antiseptic on post cesarean section infectious morbidity

Marzouk

Emarah

Zaitoun

2019

CNS

View full text Add to dashboard Cite

show abstract

“…Fifty-nine publications were subsequently retrieved for full-text review, of which 46 did not meet the inclusion criteria. Thirteen studies were eligible for inclusion in the review (n = 6023 participants) [17][18][19][20][21][22][23][24][25][26][27][28][29]. Characteristics of the included studies are outlined in Table 1.…”

Section: Resultsmentioning

confidence: 99%

Randomised Controlled Trials of Alcohol-Based Surgical Site Skin Preparation for the Prevention of Surgical Site Infections: Systematic Review and Meta-Analysis

Peel

Watson

Lee

2021

JCM

View full text Add to dashboard Cite

(1) Background: Surgical site skin preparation is an important approach to prevent postoperative wound infections. International guidelines recommend that alcohol-based combinations be used, however, the optimal combination remains uncertain. This study compares the effectiveness of alcohol-based chlorhexidine and alcohol-based iodophor for surgical site skin preparation for prevention of surgical site infections (SSIs). (2) Methods: Randomised controlled trials comparing alcohol-based interventions for surgical site skin preparation were included. The proportion of SSIs was compared using risk ratios (RR) with 95% confidence intervals (95% CI). The meta-analysis was performed with a fixed effect model using Mantel-Haenszel methods. As an a priori subgroup analysis SSI risk was examined according to different surgical procedural groups. (3) Results: Thirteen studies were included (n = 6023 participants). The use of chlorhexidine-alcohol was associated with a reduction in risk of SSIs compared with iodophor-alcohol (RR 0.790; 95% CI 0.669, 0.932). On sub-group analysis, chlorhexidine-alcohol was associated with a reduction in SSIs in caesarean surgery (RR 0.614; 95% CI 0.453, 0.831) however, chlorhexidine-alcohol was associated with an increased risk of SSI in bone and joint surgery (RR 2.667; 95% CI 1.051, 6.765). When excluding studies at high risk of bias on sensitivity analysis, this difference in alcohol-based combinations for bone and joint surgery was no longer observed (RR 2.636; 95% CI 0.995, 6.983). (4) Conclusions: The use of chlorhexidine-alcohol skin preparations was associated with a reduced risk of SSI compared to iodophor-alcohol agents. However, the efficacy of alcohol-based preparation agents may differ according to the surgical procedure group. This difference must be interpreted with caution given the low number of studies and potential for bias, however, it warrants further investigation into the potential biological and clinical validity of these findings.

show abstract

“…Skin pretreatment, among others, is important as the main source of infection is likely to be direct inoculation of the patients’ own microflora, especially from the skin and the manipulated site (Holt et al 1987; Rodrigues and Simões 2013). Antiseptic agents such as povidone-iodine, chlorhexidine gluconate and alcohol are most commonly used for skin pretreatment (Yammine and Harvey 2013).…”

Section: Introductionmentioning

confidence: 99%

Effect of chlorhexidine pretreatment on bacterial contamination at rhinoplasty field

et al. 2016

View full text Add to dashboard Cite

BackgroundThis study investigated on bacterial contamination of the rhinoplasty field. The effect of preoperative chlorhexidine treatment on decreasing bacterial contamination in the rhinoplasty field is examined. MethodsThirty patients who underwent rhinoplasty were block randomized into a chlorhexidine, regular-soap, or control group comprising ten participants each. The chlorhexidine group was subjected to chlorhexidine showering, shampooing, and facial-cleansing 12 h prior to the operation. The regular-soap group was subjected to cleansing with regular soap, and the control group did not have any skin pretreatment. Bacterial cultures were done 12 h preoperatively from nasal cavity and perinasal skin, immediately preoperatively from perinasal skin and at 1 and 2 h intraoperatively from operation field. Culture results were compared between the three groups, according to operation time, or whether infection-prone procedure was performed.ResultsThe bacterial species and colony-forming unit numbers at preoperative nasal cavity and perinasal skin were similar. In all three groups, Coagulase-negative staphylococcus was the most common bacteria found in the rhinoplasty field. The numbers of Staphylococcus aureus and Corynebacterium decreased rapidly after preoperative chlorhexidine treatment. The infection-prone procedure was associated with increased bacterial numbers over time during the operation. In all three groups, there was no postoperative infection in a follow-up period of 6 months.ConclusionRhinoplasty is confirmed as a clean contaminated operation with skin flora consistently found in the operation field. Chlorhexidine pretreatment in rhinoplasty patients has a tendency to decrease the numbers of Staphylococcus aureus and Corynebacterium on the perinasal skin.Level of evidenceRandomized controlled trial, Level I.

show abstract

Incidência de infecção do sítio cirúrgico com o preparo pré-operatório utilizando iodopolividona 10% hidroalcoólica e clorexidina alcoólica 0,5%

Abstract: The incidence of surgical site infection in operations classified as clean and as potentially contaminated for which skin preparation was done with 10% povidone-iodine and 0.5% chlorhexidine-alcohol was similar.

Cited by 33 publications

References 20 publications

Effect of preoperative vaginal cleansing using chlorhexidine antiseptic on post cesarean section infectious morbidity

Effect of preoperative vaginal cleansing using chlorhexidine antiseptic on post cesarean section infectious morbidity

Randomised Controlled Trials of Alcohol-Based Surgical Site Skin Preparation for the Prevention of Surgical Site Infections: Systematic Review and Meta-Analysis

Effect of chlorhexidine pretreatment on bacterial contamination at rhinoplasty field

Contact Info

Product

Resources

About