Objective: This study aims to assess effect of preoperative vaginal cleansing using chlorhexidine antiseptic on post cesarean section infectious morbidity. Methods: A randomized controlled trial was conducted on a random sample of 178 singleton term pregnant woman assigned for elective cesarean section. A simple random sample was recruited from the operating room of Obstetrics and Gynecology department, Zagazig University Hospitals-Egypt. Participants were randomly assigned either to conventional care group or study group. The conventional care group was exposed to the usual abdominal scrub with Povidone-iodine solution; while the study group subjected to vaginal cleansing using chlorhexidine antiseptic solution in addition to conventional preoperative care. Data were collected using an assessment sheet for demographic and clinical data and checklist for study outcomes. Results: Post intervention, assessment of the incisional wound revealed lower overall post cesarean section infectious morbidity rate among study group compared to those received conventional care (9.0% vs. 20.2% respectively; χ 2 = 4.50, p = .034). Endometritis rate was significantly lower among the study group subjects equated to those of the conventional care group (2.2% vs. 10.1% respectively; χ 2 = 4.75, p = .029), meanwhile febrile morbidity and surgical site infection rates showed non-significant reduction in favor to the study group subjects (p = .469 and .700 respectively). Conclusions: Preoperative vaginal cleansing using chlorhexidine was an effective practice for reducing post cesarean infection; where overall post cesarean infectious morbidity rate was lower among postpartum mothers subjected to vaginal cleansing compared to those exposed to conventional care alone; supporting the study hypothesis.
Background: Fetal growth restriction represents pathological inhibition of fetal growth and failure of the fetus to attain its growth potential. There is a strong association between stillbirth and fetal growth restriction. Objective: The aim of this study was to detect the relationship between Vitamin D deficiency in pregnancy and intrauterine growth restriction (IUGR).
Background: Labor is a state of uterine contractions having adequate frequency, duration, and strength resulting in cervical effacement and dilatation. Prolonged labor could cause maternal and neonatal medical issues and these unfavorable labor clinical outcomes are elevated in prolonged gestations in comparison with term pregnancies. The present study aimed to evaluate the effect of oral propranolol supplementary agent to oxytocin on Induction and Outcome of Labor and compare it with the control group (oxytocin alone). Patients and methods: This was a Randomized Controlled Clinical Trial which was conducted in Zagazig University Hospital and Zagazig General Hospital in the period between January 2021 and December 2021 to compare the efficacy of propranolol and oxytocin vs. oxytocin alone for induction of labor at 38-41 week gestational age. The study was conducted on 106 pregnant women; divided into two groups each group contain 53 pregnant women. Results: Duration of Latent Phase and Duration of 3 rd stage was significantly shorter among study group but there was no significance difference in duration of active phase and 2 nd stage between two groups. Dose of Oxytocin at which sufficient contractions occurred (3 contractions per 10 minutes) was significantly lower among the study group than the control group. Normal vaginal delivery was more frequent among the study group than among the control group: 41 cases (77.4%) versus 32 controls (60.4%). Cesarean section mode was less in the study group than the control group (p>0.05). Conclusion: Administration of oral propranolol combined with oxytocin during latent phase of labor is an effective agent in shortening the labor duration and decreasing the rate of cesarean section with no considerable side effects neither to the mother nor to her newborn has been recorded during the study.
Background: Transfer of embryos at the blastocyst stage has been associated with exceptionally high implantation rates. There are, however, only a prospective randomized studies comparing day 3 versus day 5 embryo transfers. Furthermore, the number of embryos replaced in the day 3 group transfer is often higher than the number of blastocysts replaced, thereby affecting implantation rates-Subjects & Methods: A total of 86 patients undergoing standard Intracytoplasmic sperm injection who had developed at least five 8-cell embryos, symmetrical cells and showing <11% extracellular fragmentation on day 3 were randomized for day 3 or day 5 transfer. In this prospective, randomized study the implantation and pregnancy potential of embryos transferred on day 3 or day 5 were compared-Results: There was statistically significant difference between day 3 and day 5 transfer regarding clinical pregnancy rates (29.5% versus 66.7%), implantation rates (7.9% versus 34.7%), twinning rates (2.3% versus 11.9%)-Conclusion: Higher significant difference in clinical pregnancies,implantation rate in blastocyst transfer group than cleavage transfer group so it is possible to decide on performing blastocyst transfer when having 5 or more fertilized oocytes with 8-cell embryos, symmetrical cells and showing <11% extracellularfragmentation on day 3, without risking for a transfer cancellation.
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