Ossificação heterotópica em saco herniário incisional

Melo, Renata Marques de; Mendonça, Edson Tadeu de; Mendonça, Ernesto Quaresma; Mendonça, Mateus Quaresma

doi:10.1590/s0100-69912012000200012

Cited by 5 publications

(3 citation statements)

References 7 publications

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“…The tempting possibility of using the hernial sac as part of the incisional hernia repairs, associated with the relaxing of the incisions without damaging the abdominal wall was defended by Lázaro da Silva, more than 50 years ago 10 - 12 , 27 . Soft muscle fibers, vascular neoformation and heterotopic tissues were described as an autologous graft in the peritoneal hernial sac 28 , 30 .…”

Section: Discussionmentioning

confidence: 99%

Endoscopic transposition with the hernial sac (eTHS) in ventral hernia repair - technical description

SILVA

Melo

2021

Rev. Col. Bras. Cir.

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Incisional hernia is a late complication of the most frequent after abdominal surgeries, with resulting morbidity that can worsen the condition. The treatment has been done both by open techniques, using screens or not, and by laparoscopic and robotic methods, which use them systematically. However, introducing a permanent foreign body into the tissues requires more surgical time, despite not closing the parietal defect in most cases and a higher risk of infections. New technologies have been trying to improve these results, with absorbable prostheses (biological or synthetic), but their high cost and recurrences remain a severe problem. Even so, standard repair establishes reinforcement with screens, routine, and whether the approach is traditional or mini-invasive. The authors report their first case of endoscopic repair of incisional hernia, which occurred two years ago, with a Brazilian technique already fifty years old: the transposition with the hernia sac proposed by Prof. Alcino Lázaro da Silva in 1971.

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Section: Discussionmentioning

confidence: 99%

Endoscopic transposition with the hernial sac (eTHS) in ventral hernia repair - technical description

SILVA

Melo

2021

Rev. Col. Bras. Cir.

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“…Some incidental findings in the HS, such as smooth muscle cells 3 and heterotopic ossification 4 , can be a final stage of metaplasia from primitive cells. By a similar biological process, the "epithelial-to-mesenchymal" transition of these cells, and finally to fibroblasts, is the mechanism responsible for peritoneal fibrosis that occurs in some patients undergoing peritoneal dialysis, rendering this alternative route of renal clearance unfeasible 5 .…”

Section: Introductionmentioning

confidence: 99%

Tracking stem cells in the incisional hernial sac: a gaze beyond pure tissue repairs

Melo

Neves

Menezes

2020

Rev. Col. Bras. Cir.

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Objective: the hernial sac is typically a bilayer structure consisting of connective tissue lined underneath by peritoneum. Some incidental findings on it, like smooth muscle cells and heterotopic ossification, can be explained as the end-stage metaplasia from undifferentiated cells. This study aimed to search for mesenchymal stem cells in the incisional hernial sac by an immuno-histochemistry screening test. Methods: fifteen specimens of them were submitted to histochemistry analysis using CD133 monoclonal antibodies, a specific marker of mesenchymal stem cells. The biopsies were obtained from patients submitted to pure tissue repair for incisional hernias - the transposition with the hernial sac technique (Lázaro da Silva, 1971). Results: two-thirds of the specimens expressed on average 20 (twenty) CD133+ cells in each one. Conclusion: despite the screening nature of this study, the hernial sac may be considered a source of stem cells. This could explain those abnormal findings, and perhaps the induction of new fibroblasts in procedures that use it to optimize wound healing.

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“…The etiology of HO is still uncertain. 2 It may be primary – rare and hereditary – known as progressive or secondary myositis ossificans, precipitated by musculoskeletal trauma or neurological disease. 3 In 60–75% of cases, it is a post-traumatic complication (traumatic brain injury, spinal cord injury, and surgical trauma), but it may also be associated with certain conditions, such as myelodysplasia, tabes dorsalis, large burn injuries, spinal tumors, tetanus, poliomyelitis, meningoencephalitis, and multiple sclerosis.…”

Section: Introductionmentioning

confidence: 99%

Treatment of heterotopic ossification of the hip with use of a plaster cast: case report

Souza

Aquino

Basto

2018

Revista Brasileira de Ortopedia (English Edition)

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Heterotopic ossification can be defined as the formation of bone in tissues that have no ossification properties, such as in muscles and connective tissue of a periarticular region, without invasion of the joint capsule. This pathology usually has a benign course, but it can cause a reduction in the range of joint movement and hamper the rehabilitation process. Its etiology is still unknown and it usually is originated from posttraumatic complications, affecting 10–20% of patients with traumatic brain injury. Among its clinical manifestations, it may present pain and limitation of joint movement, heat, edema, and local flushing. In some cases, it can present moderate fever, severe spasticity, and even ankylosis in more advanced stages of the disease. Treatment is based on resection of the ossification, with adjuvant measures such as non-steroidal anti-inflammatory drugs, bisphosphonate, radiotherapy, and physical therapy. None of these methods currently have a precise recommendation regarding dose, quantity, or well-established protocols. Still, the best treatment is prevention. The objective of this report is to describe a case of heterotopic ossification in the hip after traumatic brain injury, presenting the clinical manifestations and discussing the treatment instituted with a long leg plaster cast.

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Ossificação heterotópica em saco herniário incisional

Cited by 5 publications

References 7 publications

Endoscopic transposition with the hernial sac (eTHS) in ventral hernia repair - technical description

Endoscopic transposition with the hernial sac (eTHS) in ventral hernia repair - technical description

Tracking stem cells in the incisional hernial sac: a gaze beyond pure tissue repairs

Treatment of heterotopic ossification of the hip with use of a plaster cast: case report

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