Uso de plasma autólogo em dermolipectomia abdominal: nota prévia

Abstract

O plasma autólogo começou a ser estudado na década de 90, principalmente por suas propriedades adesivas, de angiogênese e pela presença de fatores de crescimento de origem plaquetária. Na verdade, o plasma pode ser isolado de modo autólogo, a partir do sangue do próprio paciente e obtido nas suas duas porções: uma com alta concentração de plaquetas (plasma rico em plaquetas- PRP) e outra com concentração baixa de plaquetas (plasma pobre em plaquetas- PPP). O presente estudo está em desenvolvimento no Hospital Universitário Clementino Fraga Filho, da Universidade Federal do Rio de Janeiro (HUCFF-UFRJ) e no Hospital Naval Marcílio Dias (HNMD), ambos no Rio de Janeiro. O objetivo é avaliar as propriedades do plasma pobre em plaquetas, principalmente a sua ação adesiva, em pacientes com indicação de dermolipectomia abdominal reparadora, de modo a reduzir as coleções no pós operatório, como hematoma e seroma, duas das principais complicações nesse tipo de cirurgia.

Efficacy of Autologous Platelet-rich Plasma Glue in Weight Loss Sequelae Surgery and Breast Reduction: A Prospective Study

“…In a study, 12 patients undergoing abdominoplasty with A-PRP glue showed a reduced time of suction drain and a decreased incidence of seroma formation. 12 In addition, Powell et al 9 have shown a benefit from using platelet gels applied unilaterally to the undersurface of the superficial muscular aponeurotic system in patients who underwent rhytidectomy, with a decrease in ecchymosis and edema in the treated side of the face compared with the untreated side. Man et al 10 have also demonstrated that the use of autologous fibrin glue, followed by the application of platelet gel in cosmetic procedures with flap creation, such as face lifts, reduction mammoplasty, and abdominoplasty resulted in many advantages, including shorter operating times, suppression of the need for drains, reduction in the need for compressive dressings, reduction in pain and postoperative swelling, and improved wound healing with an associated shorter recovery time.…”

Fibrin Sealant and Lipoabdominoplasty in Obese Grade 1 and 2 Patients

“…In a preliminary study done by Schettino et al [ 23 ], they analyzed data from 12 patients undergoing abdominoplasty using autologous plasma in its less platelet-concentrated portion (biological glue) and they found a reduction in postoperative collections, mainly seroma. The present study was carried out on 30 patients with high BMI scores who underwent lipoabdominoplasty with the usage of fibrin glue to obliterate the present dead space, and only 1 case of seroma formation occurred after removal of the drains.…”