Sarcomas de alto grau: estudo retrospectivo de 131 casos

Manoel, Wilmar José; Sarmento, Bruno José de Queiroz; Júnior, Luiz de Paula Silveira; Abreu, Deidimar Cássia Batista de; Neto, Iron Pires de Abreu; Ferreira, Erika Chaul

doi:10.1590/s0100-69912008000200004

Cited by 5 publications

(5 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Histologically, the samples were predominantly consisting of high density anaplastic spindle-shaped cells distributed along the full extent of the samples, and disorganization intense of parenchyma. The Works of Elkan (1974), Forcelledo (2003), Garner et al (2004) and Manoel et al (2008) agree that the spindle cell pattern is common in many sarcomas, and this analogy has been the cause of many mistakes when classifying them. Among spindle cell sarcomas that may present fusocellular standard, the authors cite: amelanotic melanomas, the neurofibrosarcomas, schwannoma, leiomyosarcoma, rhabdomyosarcoma, mixosarcomas and peripheral nerve sheath tumors.…”

Section: Discussionmentioning

confidence: 94%

Oral fibrosarcoma in jararaca (Bothrops pubescens): anatomopathological and immunohistochemical aspects

et al. 2015

View full text Add to dashboard Cite

RESUMO.-[Fibrossarcoma oral em jararaca (Bothrops pubescens): aspectos anatomopatológicos e imuno-histoquímicos.] Uma serpente de cativeiro, fêmea, quatro anos de idade, do gênero Bothrops apresentou aumento de volume no lado esquerdo da cavidade oral, sugerindo tratar--se de neoplasma. A massa foi removida cirurgicamente e enviada para exame anatomopatológico. Dois meses depois foi observado novo aumento de volume no mesmo local, sugerindo recidiva. A lesão foi removida por completo e também enviada para análise. Histologicamente, as duas amostras consistiam de massa altamente celular, composta por células anaplásicas fusiformes organizadas em feixes entrelaçados e distribuídos por toda extensão tecidual e, ocasionalmente, células poligonais arranjadas em fascículos irregulares. A coloração de tricrômico de Masson apresentou quantidade modesta de colágeno sustentando as células neoplásicas. Não foi observado conteúdo PAS-positivo no citoplasma das células neoplásicas. Os achados histológicos e histoquímicos indicavam tratar-se de neoplasma de célu-las fusiformes, porém não era possível sua classificação. A E-mail: acmotta@upf.br A 4-year-old female captive-bred snake of the genus Bothrops showed swelling on the left side of the oral cavity, suggesting the development of neoplasia. The mass was removed surgically and sent for pathological examination. Two months later a new increase in volume in the same site was observed, suggesting recurrence. The lesion was completely removed and sent for pathological analysis. Histologically, the two-samples consisted of a mass with highly-cell density composed of spindle-shaped anaplastic cells arranged in interwoven bundles, distributed throughout the tissue extension and, occasionally, polygonal cells arranged in irregular fascicles. The Masson trichrome staining showed modest amount of collagen supporting the neoplastic cells. PAS-positive content was not observed in the cytoplasm of neoplastic cells. Histological and histochemical findings indicated that it was a spindle cell neoplasm, but the classification was not possible. Immunohistochemistry was requested and performed using the streptavidin-biotin-peroxidase method. The markers used were anti-vimentin, anti-PCNA, anti-EMA, anti-melan A and anti-melanosome, anti--desmin, anti-actin, anti-CD68 and anti-S100protein. The neoplastic cells were immunoreactive for vimentin and PCNA and negative for the other antibodies. The morphology characterization, histochemical and immunohistochemical analysis of neoplastic cells allowed the definitive diagnosis of oral fibrosarcoma. Oral fibrosarcoma in jararaca (Bothrops pubescens): anatomopathological and immunohistochemical aspects imuno-histoquímica foi requisitada e realizada pelo método streptavidina-biotina-peroxidase, utilizando os anticorpos anti-vimentina, anti-PCNA, Anti-EMA, anti-melan A, anti--HMB45, anti-desmina, anti-actina, anti-CD68 e anti-proteí-na S-100. As células neoplásicas foram imunorreativas para vimentina e PCNA e, negativas para os demais anticorpos. A ca...

show abstract

Section: Discussionmentioning

confidence: 94%

Oral fibrosarcoma in jararaca (Bothrops pubescens): anatomopathological and immunohistochemical aspects

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Regarding STS in Brazil, we verified the presence of scarce and inconclusive epidemiological data no up-to-date records exist, nor that they incorporate non-reference treatment hospitals into statistics. ( 1 , 2 , 10 - 19…”

Section: Introductionmentioning

confidence: 99%

Epidemiological Distribution of Soft Part Tumors in a Tertiary Hospital

et al. 2022

View full text Add to dashboard Cite

Objective: To evaluate cases of soft tissue tumors at the Orthopedic Oncology service of the PUC-Campinas Hospital and determine the epidemiological profile in the period from February 2012 to November 2019, associating the participation of a non-reference hospital in the approach and treatment of the pathology. Methods: This study evaluated 72 patients aged 18 to 81 years, of both sexes and diagnosed with soft tissue tumor and divided into two groups: (I) primary etiology and (II) metastatic etiology. Results: Of 146 patients admitted, 22 resulted in deaths, with 9 patients from Group I, and 13 from Group II. For all patients with soft tissue tumor, aged between 51 and 58 years, admitted in the period, the probability of survival after 46 months was 71.84%, Group I’s was 22.7% and Group II’s 91.43%. Conclusion: Despite the scarcity of epidemiological data related to soft tissue tumor, the data appreciated in the hospital’s service, not a reference in treating this type of condition, are compatible with the data presented in specialized hospitals in Brazil, thus, in confluence with the literature. Level of Evidence III, Comparative, Prognostic and Retrospective Study.

show abstract

“…Soft-tissue sarcomas are a heterogeneous group of malignancies with different morphological patterns of mesenchymal lineage, representing about 1% of malignancies in adults [ 1 ]. Leiomyosarcomas are sarcomas derived from the smooth muscle.…”

Section: Introductionmentioning

confidence: 99%

Retromammary fat, axillary and arm metastases from a retroperitoneal leiomyosarcoma: report of a case with an indolent behaviour

Filho¹,

Melo²,

Alves³

et al. 2017

ecancer

View full text Add to dashboard Cite

Leiomyosarcomas are sarcomas that originate within smooth muscle cells and generally occur in older patients. These tumours account for 10% of all soft-tissue sarcomas. Metastases occur most commonly to the lungs, kidneys, and liver. Cutaneous metastases may also occur but are usually a very rare and late event. We present a case of a 46-year-old woman who developed subcutaneous metastasis to the axilla, arm and breast after surgical resection of the primary tumour.The patient maintained controlled disease with surgical resections and clinical follow-up, initiating chemotherapy one year after the diagnosis of metastatic disease.

show abstract

Sarcomas de alto grau: estudo retrospectivo de 131 casos

Cited by 5 publications

References 17 publications

Oral fibrosarcoma in jararaca (Bothrops pubescens): anatomopathological and immunohistochemical aspects

Oral fibrosarcoma in jararaca (Bothrops pubescens): anatomopathological and immunohistochemical aspects

Epidemiological Distribution of Soft Part Tumors in a Tertiary Hospital

Retromammary fat, axillary and arm metastases from a retroperitoneal leiomyosarcoma: report of a case with an indolent behaviour

Contact Info

Product

Resources

About