Authenticity study of Phyllanthus species by NMR and FT-IR Techniques coupled with chemometric methods

Santos, Maiara S.; Pereira-Filho, Edenir Rodrigues; Ferreira, Antônio G.; Boffo, Elisangela Fabiana; Figueira, Glyn Mara

doi:10.1590/s0100-40422012001100021

Cited by 6 publications

(1 citation statement)

References 6 publications

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“…In the case of 'ill conditioned', when the number of samples are less than the number of the measured variables, as commonly found in chemistry data, the PLS-DA may improve the classification capability of the generated predictive model [41]. Other classification techniques such as SIMCA and KNN can be carried out for authenticating HMs in combination with spectroscopy methods [42]. By employing the PCA techniques for each class, the SIMCA classification was able to be built for producing a predictive model using only the significant components [43].…”

Section: Chemometricsmentioning

confidence: 99%

Metabolite Fingerprinting Based on 1H-NMR Spectroscopy and Liquid Chromatography for the Authentication of Herbal Products

et al. 2022

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Herbal medicines (HMs) are regarded as one of the traditional medicines in health care to prevent and treat some diseases. Some herbal components such as turmeric and ginger are used as HMs, therefore the identification and confirmation of herbal use are very necessary. In addition, the adulteration practice, mainly motivated to gain economical profits, may occur by substituting the high price of HMs with lower-priced ones or by addition of certain chemical constituents known as Bahan Kimia Obat (chemical drug ingredients) in Indonesia. Some analytical methods based on spectroscopic and chromatographic methods are developed for the authenticity and confirmation of the HMs used. Some approaches are explored during HMs authentication including single-component analysis, fingerprinting profiles, and metabolomics studies. The absence of reference standards for certain chemical markers has led to exploring the fingerprinting approach as a tool for the authentication of HMs. During fingerprinting-based spectroscopic and chromatographic methods, the data obtained were big, therefore the use of chemometrics is a must. This review highlights the application of fingerprinting profiles using variables of spectral and chromatogram data for authentication in HMs. Indeed, some chemometrics techniques, mainly pattern recognition either unsupervised or supervised, were applied for this purpose.

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Section: Chemometricsmentioning

confidence: 99%