Chemical weathering rates and atmosphere/soil CO 2 consumption of igneous and metamorphic rocks under tropical climate in southeastern Brazil were evaluated using the chemical composition of surface waters and fresh rocks and soil (horizon C) in the Upper Sorocaba River basin. Surface water samples were collected between June/2009 and June/2010, and analyses were performed to assess pH, electrical conductivity (EC), temperature and total dissolved solids (TDS), including Na + , K + , Ca 2+ , Mg 2+ , Cl − , SO 4 2− , PO 4 3− , NO 3 − and SiO 2 . Fresh rocks and C horizon samples were also collected, taking into account their geological context, abundance and spatial density, to analyze major elements and mineralogy. The concentration of TDS and dissolved cations, anions and silica increased during the dry period in relation to the wet period, and the same behavior was observed for pH, EC and temperature. After corrections of anthropogenic contributions (ca. 21 t/km 2 /yr) and atmospheric inputs (ca. 19 t/km 2 /yr), the annual flux due to chemical weathering involving the igneous and metamorphic rocks was ca. 29 t/km 2 /yr. The CO 2 atmospheric/soil consumption in the Upper Sorocaba River basin was ca. 0.2 × 10 6 mol/km 2/ yr, and when extrapolated to the entire Mantiqueira Orogenic Belt, accounted an estimated consumption of 0.07 × 10 12 mol/yr, representing 0.6% of the total CO 2 consumption flux derived from global average silicate weathering. The chemical weathering rates of igneous and metamorphic rocks in the Upper Sorocaba River basin were estimated at 15 m/My, respectively. The main weathering process in this watershed was the monossialitization, with partial hydrolyses of bedrock minerals, except quartz, which was not weathered and remained in the soil profile. The annual specific flux derived from igneous and metamorphic rocks at Upper Sorocaba River basin could be compared with watersheds in tropical climates. However, this value is higher than in other North American, European, Asian and African granitoid watersheds, and lower than in montane watersheds. Anthropogenic and atmospheric influence Water-rock interactions the basic function of moderating the Earth's climate. The physical erosion is related to soil loss, acts on the weathered surface by removing the cover and carrying the particulate matter. In both processes, the dissolved and particulate materials are transported through rivers to the oceans, resulting in the deposition of Ca and Mg carbonates (and smaller amounts of Fe and Mn) and sediments, respectively.The chemical weathering can be evaluated from the silica mass balance or from models using the dissolved sodium, calcium, potassium, magnesium and silica and total dissolved load concentrations, where inputs from rainfall require corrections (Amiotte-Suchet and Probst, 1993; Bain et al.