Constituintes químicos das flores de Pterogyne nitens (Caesalpinioideae)

Regasini, Luís Octávio; Fernandes, Daniara Cristina; Castro‐Gamboa, Ian; Silva, Dulce Helena Siqueira; Furlan, Maysa; Bolzani, Vanderlan da Silva; Barreiro, Eliezer J.; Cardoso-Lopes, Elaine Monteiro; Young, Maria Cláudia Marx; Torres, Luce Brandão; Vellosa, José Carlos Rebuglio; Oliveira, Olga Maria Mascarenhas de Faria

doi:10.1590/s0100-40422008000400018

Cited by 30 publications

(18 citation statements)

References 8 publications

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“…A quercetina 3-O-β-D-glicosídeo foi isolada de Prangos ferulaceae (Apiaceae) (Razavi et al, 2009), Euphorbia retusa (Euphorbiaceae) (Harraz, 2009), Rosa nutkana (Rosaceae) (Jovel et al, 2007) e de Desmostachia bipinnata (Gramineae) (Awaad et al, 2008). A quercetina 3-Osoforosídeo também está presente em Pterogyne nitens (Caesalpinioideae) (Regasini et al, 2008) e Bassia muricata (Chenopodiaceae) (Kamel et al, 2001), enquanto que das espécies Salicornia herbacea (Chenopodiaceae) (Lee et al, 2005) e Astragalus corniculatus (Fabaceae) (Krasteva et al, 2008) já foi isolada a isoraminetina 3-glicosídeo.…”

Section: Resultsunclassified

Flavonoides e atividade antioxidante em Palicourea rigida Kunth, Rubiaceae

Rosa¹,

Silva²,

Silva³

et al. 2010

Rev. bras. farmacogn.

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RESUMO:A atividade antioxidante, avaliada pelo método DPPH (1,1-difenil-2-picrilidrazila), e o teor em compostos fenólicos totais do extrato bruto metanólico e frações das folhas da espécie Palicourea rigida Kunth, Rubiaceae, foram quantificadas neste trabalho. Apesar da baixa atividade apresentada pelo extrato bruto (500 ppm), a fração acetato de etila apresentou atividade moderada (192 ppm) e o maior teor de fenólicos totais dentre as frações ensaiadas. Assim, a fração acetato de etila foi submetida a procedimentos cromatográficos o que resultou no isolamento dos flavonoides quercetina 3-O-β-D-glicosídeo, quercetina 3-O-soforosídeo e isoraminetina 3-glicosídeo, cujas estruturas foram elucidadas por análise espectroscópica, incluindo RMN (1D e 2D) e comparação com os dados da literatura.Unitermos: Rubiaceae, Palicourea, flavonoides, atividade antioxidante.ABSTRACT: "Flavonoids and antioxidant activity in Palicourea rigida Kunth, Rubiaceae". The antioxidant activity, evaluated by DPPH (1,1-difenil-2-picrilidrazila) method, and the determination of the total phenolic compounds of the crude methanolic extract and fractions of the Palicourea rigida Kunth, Rubiaceae, leaves were quantified in this work. Despite weak activity exhibited by crude extract (500 ppm), the fraction ethyl acetate showed moderate activity (192 ppm), and the largest value for the phenolic compounds among all the assayed fractions. Then, the ethyl acetate fraction was submitted to the chromatography procedures which led to the isolation of the flavonoid quercetin 3-O-D-glicoside, quercetin 3-O-sophoroside and isorhamnetin 3-glicoside, which had the structures elucidated by spectroscopy analysis, including RMN (1D and 2D) and comparison with literature data.

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Section: Resultsunclassified

Flavonoides e atividade antioxidante em Palicourea rigida Kunth, Rubiaceae

Rosa¹,

Silva²,

Silva³

et al. 2010

Rev. bras. farmacogn.

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“…citri subsp. citri activity of gallic acid (3,4,5-trihydroxybenzoic acid), an intermediate of the hydrolysable tannin biosynthesis pathway in plants ( [13][14][15] which, together with its natural and semisynthetic derivatives, has been associated with a broad spectrum of biological actions (16)(17)(18)(19)(20)(21). Moreover, gallic acid and derivatives demonstrated antimicrobial properties.…”

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confidence: 99%

Antibacterial Activity of Alkyl Gallates against Xanthomonas citri subsp. citri

et al. 2013

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The plant-pathogenic bacterium Xanthomonas citri subsp. citri is the causal agent of Asiatic citrus canker, a serious disease that affects all the cultivars of citrus in subtropical citrus-producing areas worldwide. There is no curative treatment for citrus canker; thus, the eradication of infected plants constitutes the only effective control of the spread of X. citri subsp. citri. Since the eradication program in the state of São Paulo, Brazil, is under threat, there is a clear risk of X. citri subsp. citri becoming endemic in the main orange-producing area in the world. Here we evaluated the potential use of alkyl gallates to prevent X. citri subsp. citri growth. These esters displayed a potent anti-X. citri subsp. citri activity similar to that of kanamycin (positive control), as evaluated by the resazurin microtiter assay (REMA). The treatment of X. citri subsp. citri cells with these compounds induced altered cell morphology, and investigations of the possible intracellular targets using X. citri subsp. citri strains labeled for the septum and centromere pointed to a common target involved in chromosome segregation and cell division. Finally, the artificial inoculation of citrus with X. citri subsp. citri cells pretreated with alkyl gallates showed that the bacterium loses the ability to colonize its host, which indicates the potential of these esters to protect citrus plants against X. citri subsp. citri infection.

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“…A MPO é uma heme-enzima considerada responsável pela resposta imunológica inespecífica a vários agentes. 12 Os resultados mostraram que a administração na dose de 5,0 mg/orelha inibiu a atividade sobre a enzima em 0,3; 17; 61,7; 67,1; 86,4; 78,8; 77,0 e 50,9% nos extratos EBF e EBG e as frações FAEF, FAEG, FBF, FBG, FAF e FAG, respectivamente. O processo anti-inflamatório tópico pode ser promovido por diferentes mediadores na formação do edema.…”

Section: Resultsunclassified