Essential oils from leaves of cryptocarya spp from the atlantic rain forest

Telascrea, Marcelo; Araújo, Carla C. de; Cavalheiro, Alberto José; Marques, Márcia Ortiz Mayo; Facanali, Roselaine; Moraes, Pedro Luís Rodrigues de

doi:10.1590/s0100-40422008000300007

Cited by 8 publications

(10 citation statements)

References 9 publications

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“…The major constituents identified were: limonene (42.3%), linalool (9.7%) and nerolidol (8.6%). The chemical composition observed in the present study was similar to the chemical composition already described in the literature for other species belonging to the same genus (Telascrea et al 2008).…”

Section: Resultssupporting

confidence: 90%

“…The genus Cryptocarya comprises about 350 species distributed mainly in Malaysia and Australia. Twenty-three species occur in South America and, among them, C. mandioccana, C. moschata, C. saligna and C. bothelhensis have already had the chemical composition of their essential oils previously identified (Telascrea et al 2008). However, no reports were found in the literature on the chemical composition of the leaf essential oils of C. aschersoniana nor their anti-Leishmania amazonensis and cytotoxic activities.…”

Section: Introductionmentioning

confidence: 99%

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Chemical composition and evaluation of antileishmanial and cytotoxic activities of the essential oil from leaves of Cryptocarya aschersoniana Mez. (Lauraceae Juss.)

Andrade

Melo

Alcoba

et al. 2018

An. Acad. Bras. Ciênc.

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Leishmaniasis is an endemic disease caused by protozoa of the genus Leishmania, which affects around two million people worldwide. One major drawback in the treatment of leishmaniasis is the emergence of resistance to current chemotherapeutics. Medicinal and aromatic plants constitute a major source of natural organic compounds. In this study, the leaf essential oil of Cryptocarya aschersoniana was obtained by hydrodistillation in a Clevenger-type apparatus, and the chemical composition was analyzed by GC-MS and GC-FID. The essential oil of these species was predominantly constituted by monoterpene hydrocarbons (48.8%). Limonene (42.3%), linalool (9.7%) and nerolidol (8.6%) were the main constituents in the oil of C. aschersoniana. The in vitro activity of the oil was evaluated against the promastigote forms of Leishmania amazonensis, the causative agent of cutaneous leishmaniasis in humans. The essential oil of C. aschersoniana showed high activity against L. amazonensis promastigote forms (IC 50 = 4.46 µg/mL), however, it also demonstrated a relatively high cytotoxicity on mouse peritoneal macrophages (CC 50 = 7.71 µg/mL). This is the first report of the chemical composition and the leishmanicidal and cytotoxic activities of the leaf essential oil of C. aschersoniana.

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Section: Resultssupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

Chemical composition and evaluation of antileishmanial and cytotoxic activities of the essential oil from leaves of Cryptocarya aschersoniana Mez. (Lauraceae Juss.)

Andrade

Melo

Alcoba

et al. 2018

An. Acad. Bras. Ciênc.

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“…Compounds derived from nerolydil cation ( 39 ), such as ( E , Z )‐farnesyl cation ( 31 ) through the cis‐ germacryl cation ( 30 ) pathway were also identified as minor compounds in the leaf EO. Most of the components we identified in the C. sylvestris leaf EO originated from the ( E , E )‐farnesyl cation ( 19 ) pathway, by means of cyclization between either carbons 1 and 11 (C1–C11), to form the humulyl cation ( 37 ) and its derivatives, or carbons 1 and 10 (C1–C10), to form the germacryl cation ( 38 ) and its derivatives [39] …”

Section: Resultsmentioning

confidence: 99%

Casearia sylvestris Essential Oil Degradation Products Generated by Leaf Processing

Carvalho

Oda

Crevelin

et al. 2021

Chemistry & Biodiversity

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Casearia sylvestris is an endemic tree of the Latin America that the essential oil (EO) has anti‐inflammatory and gastroprotective actions. This study evaluates the chemical composition of the EO from the volatile fractions of in natura, fresh, and dried C. sylvestris var. sylvestris and var. lingua leaves. For both varieties, the dried leaves presented higher EO yield as compared to fresh leaves. The major EO chemical components were (E)‐caryophyllene, α‐humulene, germacrene D, bicyclogermacrene, spathulenol, caryophyllene oxide, and humulene epoxide II. In both varieties, the content of sesquiterpene hydrocarbons decreased and oxygenated sesquiterpenes increased on going from in natura to fresh and dried leaves, which indicated that leaf drying and hydrodistillation modified the volatile composition. The results also suggested that bicyclogermacrene and (E)‐caryophyllene were oxidized during processing, to generate spathulenol and caryophyllene oxide, respectively. C. sylvestris varieties and in natura, fresh, and dried leaves differed in terms of the chemical composition of volatiles, which could affect the EO biological activities.

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“…Na maioria dos óleos essenciais de Lauraceae reportados na literatura observa-se a predominância de sesquiterpenos, principalmente de hidrocarbonetos sesquiterpênicos (Gottlieb et al, 1981;Cicció & Chaverri, 2008;Telascrea et al, 2008).…”

Section: Resultsunclassified

Composição química e atividade biológica dos óleos essenciais das folhas e caules de Rhodostemonodaphne parvifolia Madriñán (Lauraceae)

et al. 2010

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RESUMOOs óleos essenciais das folhas e caules de Rhodostemonodaphne parvifolia coletada na Reserva Florestal Adolpho Ducke foram obtidos por hidrodestilação e analisados por cromatografia em fase gasosa com detector de ionização de chama e espectrometria de massas. Treze constituintes foram identificados nas folhas, dos quais o b-cariofileno foi o que apresentou maior percentual (41,30%). Nos caules foram identificados quinze compostos, com predominância dos sesquiterpenos b-cariofileno (16,20%) e epi-cedrol (13,30%) e do monoterpeno linalol (15,40%). Os óleos foram analisados em ensaios químicos, de sequestro do radical livre DPPH, e enzimáticos, de inibição da enzima acetilcolinesterase. Nos ensaios de sequestro de radicais livres, apesar de terem se mostrado ativos em ensaios qualitativos, os óleos essenciais apresentaram fraca atividade antioxidante no ensaio quantitativo (inativos em concentração inferior a 1.000 mg/mL). A inibição da acetilcolinesterase só foi observada nos óleos essenciais das folhas. A composição química e a atividade biológica destes óleos estão sendo relatadas pela primeira vez neste trabalho. PALAVRAS-CHAVE:Rhodostemonodaphne parvifolia, óleo essencial, antioxidante, anticolinesterase. Composition and biology activity of essential oils from leaves and stems of Rhodostemonodaphne parvifolia Madriñán (Lauraceae) ABSTRACTThe essential oils of leaves and stems of Rhodostemonodaphne parvifolia collected in the Adolpho Ducke Forest Reserve were obtained by hydrodistillation and analyzed by GC-FID and GC-MS. Thirteen components were identified in the leaf oil, of which b-caryophyllene was the major (41.30%). Fifty components were identified in the stem oil, among them the sesquiterpenes b-caryophyllene (16.20%) and epi-cedrol (13.30%), together with the monoterpene linalool (15.40%). The essential oils were analyzed at chemical, DPPH free radical scavenging; and enzymatic bioassays, acetylcholinesterase inhibition. At antioxidant DPPH assays, the oils showed to be active at the qualitative assay but only weakly active at quantitative test (inactive at concentration lower than 1,000 mg/mL). The inhibition of acetylcholinesterase was detected only in leaves essential oils. This paper describes for the first time the composition of these essential oils and their biological activities.

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Essential oils from leaves of cryptocarya spp from the atlantic rain forest

Cited by 8 publications

References 9 publications

Chemical composition and evaluation of antileishmanial and cytotoxic activities of the essential oil from leaves of Cryptocarya aschersoniana Mez. (Lauraceae Juss.)

Chemical composition and evaluation of antileishmanial and cytotoxic activities of the essential oil from leaves of Cryptocarya aschersoniana Mez. (Lauraceae Juss.)

Casearia sylvestris Essential Oil Degradation Products Generated by Leaf Processing

Composição química e atividade biológica dos óleos essenciais das folhas e caules de Rhodostemonodaphne parvifolia Madriñán (Lauraceae)

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