Ocorrência de flavonas, flavonóis e seus glicosídeos em espécies do gênero Solanum (Solanaceae)

Abstract

Recebido em 11/3/02; aceito em 23/1/03 OCCURRENCE OF FLAVONES AND FLAVONOLS AGLYCONES AND ITS GLYCOSIDES IN Solanum (SOLANACEAE).During the last decades several flavonoids of Solanum species have been isolated. This review describes the flavones, flavonols and their glycosides presently known as constituents of Solanum species.

Other chemical constituents isolated from Solanum crinitum Lam. (Solanaceae)

“…, cis-(10) and trans-(11) cumaric acids and ethyl cis- (8) and trans-(9) cumarate esters and 4-hydroxybenzoic acid (12); from green fruits methanolic extracts were isolated three tri-glycosyl-steroidal alkaloids, solamargine (13), 20-epi-solamargine (14) and solasonine (16). The derivatives 3,5,7,4'-tetramethylkaempferol (4), 3,7,4'-trimethylkaempferol (5), 3,7,4'-trimethyl-5-acetylkaempferol (6), the peracetyl-20-epi-solamargine (15) and peracetyl-solasonine (17) were prepared.…”

“…[15][16][17][18] The first report of 1 in Solanum species was made by Souza et al 14 Kaempferol and astragalin have been isolated from some Solanum species. 8 The treatment of 3 with diazomethane yielded the methyl derivatives 4 and 5, described in the literature, 19 and the derivative 6 was obtained by treating 5 with Ac 2 O/Pyridine. The 2D NMR spectra, including NOESY experiments, of these derivatives were used to confirm the proposed structure of 3 and to carry out the complete assignment of the 1 H and 13 C chemical shifts of 6 (see Experimental).…”

“…[6][7][8] Solanum crinitum Lam (Solanaceae), popularly known as "jurubeba" and "fruto-de-lobo", is a shrub or small tree in South America, including southern Brazil and Colombia. 9,10 In the course of our pharmacological and phytochemical investigations of Solanum species, 3,4,8,[11][12][13] we have reported the cytotoxic and antitumoral activities of flavonoids isolated from trichomes of young branches Other Chemical Constituents Isolated from Solanum crinitum Lam. (Solanaceae) J. Braz.…”

“…[6][7][8] Solanum crinitum Lam (Solanaceae), popularly known as "jurubeba" and "fruto-de-lobo", is a shrub or small tree in South America, including southern Brazil and Colombia. 9,10 In the course of our pharmacological and phytochemical investigations of Solanum species, 3,4,8,[11][12][13] we have reported the cytotoxic and antitumoral activities of flavonoids isolated from trichomes of young branches and also of a rich glycoalkaloids total fraction from the green fruits of Solanum crinitum Lam 14 along with its allelopathic activity. 3 This work describes the isolation and structural characterization of the flavonoids tiliroside (1), astragalin (2) (7), cis-(10) and trans-(11) cumaric acids and ethyl cis- (8) and trans-(9) cumarate and 4-hydroxybenzoic acid (12), which were isolated from the trichomes, and the glycoalkaloids solamargine (13), 20-epi-solamargine (14) and solasonine (16) isolated from the green fruits.…”

“…9,10 In the course of our pharmacological and phytochemical investigations of Solanum species, 3,4,8,[11][12][13] we have reported the cytotoxic and antitumoral activities of flavonoids isolated from trichomes of young branches and also of a rich glycoalkaloids total fraction from the green fruits of Solanum crinitum Lam 14 along with its allelopathic activity. 3 This work describes the isolation and structural characterization of the flavonoids tiliroside (1), astragalin (2) (7), cis-(10) and trans-(11) cumaric acids and ethyl cis- (8) and trans-(9) cumarate and 4-hydroxybenzoic acid (12), which were isolated from the trichomes, and the glycoalkaloids solamargine (13), 20-epi-solamargine (14) and solasonine (16) isolated from the green fruits. The derivatives 3,5,7,4'-tetra-Omethyl-kaempferol (4), 3,7,4'-tri-O-methyl-kaempferol (5), 3,7,4'-tri-O-methyl-5-O-acetyl-kaempferol (6), peracetyl-epi-solamargine (15) and peracetyl-solasonine (17) were prepared and used to confirm the structures of the natural compounds.…”