Avaliação dos insulinomas pela ultra-sonografia intra-operatória: estado atual do tema

Rosa, Ana Cláudia Ferreira; Machado, Márcio Martins; Lemes, Marcella Stival; Barreto, Mariana Caetano; Nunes, Rodrigo Alvarenga; Barros, Nestor de; Mota, Orlando Milhomem da; Silva, Osterno Queiroz da; Benevides, Jales; Barreto, Paulo Adriano; Cerri, Giovanni Guido

doi:10.1590/s0100-39842006000500012

Cited by 2 publications

(3 citation statements)

References 23 publications

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“…The test of hypoglycemia with fasting is widely accepted to obtaining a diagnosis with great positiveness, as demonstrated in the present series 5,11 . After confirmed the diagnosis, the challenge is the tumor location, since in the great majority they are small tumors, as well as in this present study, which largely had less than 1.5 cm at its greatest diameter 9,10 . There are several methods of imaging available, being necessary usually more than one for location of the lesion.…”

Section: Discussionsupporting

confidence: 49%

“…In this sample, the tumor was slightly more prevalent in the pancreatic head, and the literature shows equal distribution in the pancreatic parenchyma 2,3,9 . There were no deaths.…”

Section: Discussionmentioning

confidence: 52%

“…The preferred treatment is surgery, performed in a conventional or laparoscopic manner, and with or without additional method for intraoperative location of the lesion 1,9,11 . The present study aims to analyze the clinical, epidemiological, pathological and surgical patients treated in the last decade in two surgical services.…”

Section: Introductionmentioning

confidence: 99%

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Tratamento cirúrgico dos insulinomas do pâncreas

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Coelho

Petruzzielo

et al. 2012

ABCD, arq. bras. cir. dig.

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Section: Discussionsupporting

confidence: 49%

“…In this sample, the tumor was slightly more prevalent in the pancreatic head, and the literature shows equal distribution in the pancreatic parenchyma 2,3,9 . There were no deaths.…”

Section: Discussionmentioning

confidence: 52%

See 1 more Smart Citation

Tratamento cirúrgico dos insulinomas do pâncreas

Bonato

Coelho

Petruzzielo

et al. 2012

ABCD, arq. bras. cir. dig.

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Management of Insulinomas: Analysis from a Tertiary Care Referral Center in India

et al. 2008

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The aim of this study was to describe the localization and management of patients with pancreatic insulinomas and determine the most effective localization and surgical techniques in the presence of significant financial constraints in the patient population. We retrospectively reviewed the case records of 18 patients with insulinomas treated at our institution over a period of 10 years. The medical records were reviewed for demographic data, clinical presentation, biochemistry, details of localization studies, intraoperative findings, postoperative outcome, and long-term follow-up. The sensitivities of the various localization procedures were calculated using the intraoperative findings as the gold standard. There were 10 men and 8 women in the study, with a median age of 43 years. All patients underwent a supervised 72-hour fast and developed symptomatic hypoglycemia within 48 hours. An average of 1.9 localization procedures was performed per patient. Computed tomography (CT) had a sensitivity of 62% and specificity of 100%. Magnetic resonance imaging and digital subtraction angiography had specificities of 85% and 100%, respectively, with a specificity of 66% and 50%, respectively. Fourteen patients underwent surgery. Intraoperatively the excised tumor was palpable in nine patients, and all patients had postoperative euglycemia. In five patients the tumor was not palpable during the time of surgery; three of these patients underwent blind distal pancreactomy, with two patients having persistent hypoglycemia during the postoperative period. Two patients had a negative exploratory laparotomy. Patients with a surgical cure were followed up for a mean period of 24 months. On the background of financial constraints in connection with patient care, CT scanning is a cost-effective option with good specificity. Intraoperative palpation of the tumor and enucleation is the most effective technique for surgical cure. Blind distal pancreactomy is not advocated for tumors that are not localized intraoperatively.

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Avaliação dos insulinomas pela ultra-sonografia intra-operatória: estado atual do tema

Cited by 2 publications

References 23 publications

Tratamento cirúrgico dos insulinomas do pâncreas

Tratamento cirúrgico dos insulinomas do pâncreas

Management of Insulinomas: Analysis from a Tertiary Care Referral Center in India

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