Tomografia computadorizada de alta resolução do tórax na asbestose precoce

Abstract

Tomografia computadorizada de alta resolução do tórax na asbestose precoce.

Idiopathic interstitial pneumonias: review of the latest American Thoracic Society/European Respiratory Society classification

“…Among all IIPs ( 10 ) , idiopathic pulmonary fibrosis is the most common; it is an interstitial lung disease of unknown cause, characterized histologically by the usual interstitial pneumonia pattern ( 11 , 12 ) , with dispersed fibroblastic foci and heterogeneous involvement of the parenchyma, areas of tissue preservation being interspersed with areas of interstitial inflammation and honeycombing. It occurs mainly in adults over 50 years of age who are smokers or former smokers, typically manifesting as progressive dyspnea and dry cough.…”

“…Nonspecific interstitial pneumonia is characterized histologically by homogeneous inflammation and expansion of the alveolar walls, with or without fibrosis; it can be classified as belonging to one of three subtypes ( 11 ) : cellular (less common and with a better prognosis); fibrotic (with a worse prognosis); or mixed. Nonspecific interstitial pneumonia can be idiopathic, although it most often manifests as pulmonary symptoms associated with connective tissue diseases (especially scleroderma), hypersensitivity pneumonia, drug reactions, or diffuse alveolar damage.…”

“…Desquamative interstitial pneumonia is a rare disease that is strongly associated with smoking; in some cases, it progresses to respiratory failure and advanced pulmonary fibrosis ( 8 ) . Histopathological findings include homogeneous thickening of the alveolar septa and intra-alveolar accumulation of pigmented macrophages ( 11 ) . Men between 30 and 50 years of age constitute the majority of patients; after smoking cessation and corticosteroid therapy, there is significant improvement of the symptoms ( 11 ) .…”

“…Histopathological findings include homogeneous thickening of the alveolar septa and intra-alveolar accumulation of pigmented macrophages ( 11 ) . Men between 30 and 50 years of age constitute the majority of patients; after smoking cessation and corticosteroid therapy, there is significant improvement of the symptoms ( 11 ) .…”

“…Classically characterized by the combination of interstitial disease and respiratory bronchiolitis, the typical histological findings of respiratory bronchiolitis-associated interstitial lung disease include the accumulation of pigmented macrophages in the respiratory bronchioles, alveolar ducts, and adjacent alveoli, together with minimal fibrosis and inflammatory infiltrate ( 11 ) . The affected patients are usually men between 30 and 50 years of age who have few or no symptoms.…”