Susceptibility and resistance to deltamethrin of wild and domestic populations of Triatoma infestans (Reduviidae: Triatominae) in Bolivia: new discoveries

Depickère, Stéphanie; Buitrago, Rosio; Siñani, Edda; Baune, Marianne; Monje, Marcelo; López, Ronald; Waleckx, Etienne; Chávez, Tamara; Brenière, Simone Frédérique

doi:10.1590/s0074-02762012000800013

Cited by 41 publications

(49 citation statements)

References 21 publications

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“…In addition to this important problem, in the last few years, wild foci of T. infestans have been described, mainly in the Inter-Andean Valleys and in the Gran Chaco [8,9]. This fact was also observed in Argentina, Paraguay and Chile, showing that wild T. infestans have dispersed more widely than expected [10][11][12][13][14]. In Bolivia, the epidemiological significance of wild foci of T. infestans has been stressed [10].…”

Section: Introductionmentioning

confidence: 99%

“…It is considered that vector control failures, are due to high levels of insecticide resistance in this area [18][19][20][21]. In the last few years, more studies demonstrated that the phenomenon of resistance to insecticides in domestic T. infestans populations presents an extensive distribution in southern Bolivia and northern Argentina [21][22][23], with high resistance ratios, and different toxicological profiles [14,18,19,[24][25][26]. Recently, susceptibility and resistance to deltamethrin and fipronil were detected in wild populations of T. infestans from Bolivia [14,27].…”

Section: Introductionmentioning

confidence: 99%

“…Coincidence or not, it is in those regions that the reach of the vector control strategies is limited, and insecticide resistance in T. infestans populations has been reported, including wild populations [14,[27][28][29]. Thus, this study proposes to characterize the susceptibility to deltamethrin of wild and domestic T. infestans from the Gran Chaco and Inter-Andean Valleys in Bolivia, in order to understand better the extent of this relevant problem.…”

Section: Introductionmentioning

confidence: 99%

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Susceptibility to deltamethrin of wild and domestic populations of Triatoma infestans of the Gran Chaco and the Inter-Andean Valleys of Bolivia

Gomez

D¿Avila

Orellana

et al. 2014

Parasites & Vectors

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Background: The persistence of Triatoma infestans and the continuous transmission of Trypanosoma cruzi in the Inter-Andean Valleys and in the Gran Chaco of Bolivia are of great significance. Coincidentally, it is in these regions the reach of the vector control strategies is limited, and reports of T. infestans resistance to insecticides, including in wild populations, have been issued. This study aims to characterize the susceptibility to deltamethrin of wild and domestic populations of T. infestans from Bolivia, in order to better understand the extent of this relevant problem. Methods: Susceptibility to deltamethrin was assessed in nine, wild and domestic, populations of T. infestans from the Gran Chaco and the Inter-Andean Valleys of Bolivia. Serial dilutions of deltamethrin in acetone (0.2 μL) were topically applied in first instar nymphs (F1, five days old, fasting, weight 1.2 ± 0.2 mg). Dose response results were analyzed with PROBIT version 2, determining the lethal doses, slope and resistance ratios (RR). Qualitative tests were also performed. Results: Three wild T. infestans dark morph samples of Chaco from the Santa Cruz Department were susceptible to deltamethrin with RR 50 of <2, and 100% mortality to the diagnostic dose (DD); however, two domestic populations from the same region were less susceptible than the susceptibility reference lineage (RR 50 of 4.21 and 5.04 respectively and 93% DD). The domestic population of Villa Montes from the Chaco of the Tarija Department presented high levels of resistance (RR 50 of 129.12 and 0% DD). Moreover, the domestic populations from the Valleys of the Cochabamba Department presented resistance (RR 50 of 8.49 and 62% DD), the wild populations were less susceptible than SRL and T. infestans dark morph populations (RR 50 < 5). Conclusion: The elimination of T. infestans with pyrethroid insecticides in Brazil, Uruguay, Chile, and its drastic reduction in large parts of Paraguay and Argentina, clearly indicates that pyrethroid resistance was very uncommon in non-Andean regions. The pyrethroid susceptibility of non-Andean T. infestans dark morph population, and the resistance towards it, of Andean T. infestans wild and domestic populations, indicates that the Andean populations from Bolivia are less susceptible.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Susceptibility to deltamethrin of wild and domestic populations of Triatoma infestans of the Gran Chaco and the Inter-Andean Valleys of Bolivia

Gomez

D¿Avila

Orellana

et al. 2014

Parasites & Vectors

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“…Three major obstacles have been identifi ed when interpreting the results obtained by studies on Triatomines resistance to insecticides; namely: I) a wide range of methodologies, despite the existence of a single guiding protocol (27) (36) (38) (42) (43) (46) (47) (53) (55) (56) ; II) a lack of information about the real impact of resistance ratios in the fi eld; and III) the concept of the Susceptibility Reference Lineage (SRL). The fi rst shortcoming of studies on Triatominae resistance to insecticides is that, at present, there is only one guiding protocol for studies on insect susceptibility to insecticides, i.e., the one provided by the WHO (69) .…”

Section: Methodological Difficultiesmentioning

confidence: 99%

“…In trials with fi pronil, the susceptibility of a domestic population of T. infestans collected from Mataral was also assessed; the RR 50 ranged from 0.5 to 45.6 in the wild populations and ranged from 139.2 in the domestic population. Depickére et al (27) characterized the susceptibility of 20 Bolivian populations collected from La Paz, Cochabamba, Potosi, Santa Cruz, and Tarija (12 wild populations and 8 domestic populations) to deltamethrin. The dose-diagnostic tests revealed that all wild populations were susceptible to deltamethrin, except for the Julo Grande population (Toro-Toro/Potosi).…”

Section: History Of Triatominae Resistance To Insecticidesmentioning

confidence: 99%

History of insecticide resistance of Triatominae vectors

Pessoa

Viñas²,

Rosa

et al. 2015

Rev. Soc. Bras. Med. Trop.

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In the last 15 years, different types of Triatominae resistance to different insecticides have been reported; thus, resistance may be more widespread than known, requiring better characterization and delimitation, which was the aim of this review. This review was structured on a literature search of all articles from 1970 to 2015 in the PubMed database that contained the keywords Insecticide resistance and Triatominae. Out of 295 articles screened by title, 33 texts were selected for detailed analysis. Insecticide resistance of Triatomines is a complex phenomenon that has been primarily reported in Argentina and Bolivia, and is caused by different factors (associated or isolated). Insecticide resistance of Triatominae is a characteristic inherited in an autosomal and semi-dominant manner, and is polygenic, being present in both domestic and sylvatic populations. The toxicological profi le observed in eggs cannot be transposed to different stages of evolution. Different toxicological profi les exist at macro-and microgeographical levels. The insecticide phenotype has both reproductive and developmental costs. Different physiological mechanisms are involved in resistance. Studies of Triatomine resistance to insecticides highlight three defi ciencies in interpreting the obtained results: I) the vast diversity of methodologies, despite the existence of a single guiding protocol; II) the lack of information on the actual impact of resistance ratios in the fi eld; and III) the concept of the susceptibility reference lineage. Research on the biological and behavioral characteristics of each Triatominae species that has evolved resistance is required in relation to the environmental conditions of each region.

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Chagas Disease Vector Control

Gürtler

Cecere

2021

Triatominae - The Biology of Chagas Disease Vectors

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Susceptibility and resistance to deltamethrin of wild and domestic populations of Triatoma infestans (Reduviidae: Triatominae) in Bolivia: new discoveries

Abstract: Bolivia is a high-endemic country for Chagas disease, for which the principal vector is

Cited by 41 publications

References 21 publications

Susceptibility to deltamethrin of wild and domestic populations of Triatoma infestans of the Gran Chaco and the Inter-Andean Valleys of Bolivia

Susceptibility to deltamethrin of wild and domestic populations of Triatoma infestans of the Gran Chaco and the Inter-Andean Valleys of Bolivia

History of insecticide resistance of Triatominae vectors

Chagas Disease Vector Control

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