Detection and molecular characterization of group A rotavirus from hospitalized children in Rio de Janeiro, Brazil, 2004

Abstract

Rotavirus is a major cause of infantile acute diarrhea

Genotyping of gastroenteric viruses in hospitalised children: first report of norovirus GII.21 in Brazil

“…[n = 6 (10.5%)]. The results are consistent with a previous study performed in samples from hospitalised children in RJ (Carvalho-Costa et al 2006, 2011, Leite et al 2008. Previously, the G1 genotype was the most common genotype found worldwide and this genotype is the component of the attenuated monovalent RVA vaccine (Rotarix ® ) that was licensed for routine infant immunisation in Brazil in 2006 (Leite et al 2008).…”

“…Due to the short evaluation period of this study, the seasonality of the viruses could not be inferred; however, the timing of the RVA and NoV infections (p = 0.0149) confirmed previous findings demonstrating increased positivity during the driest months (June-August) of the year in Southwest Brazil (Bittencourt et al 2000, Araújo et al 2002, Carvalho-Costa et al 2006.…”

“…More than 50% of the AGE cases investigated in this study were in children aged up to six months, reflecting the well-established trend that this viral infection is more severe in very young children (Barnes et al 1998, Carvalho-Costa et al 2006). In addition, NoV was detected in 55.5% (10/18) of the children aged more than one year and in 22.9% (14/61) of the children under one year of age and this difference was statistically significant (p = 0.0187).…”

Rotavirus and adenovirus in Rondônia

“…In Brazil, several studies have reported frequencies of rotavirus infection between 20-70%, especially in younger children (Santos et al 2002, Luz et al 2005, Carvalho-Costa et al 2006. Our results are comparable to those from large cities of different states which showed the occurrence of rotavirus at a rate of approximately 23% among infants hospitalized for acute diar- Number of positive (Frequency %) Number of positive (Frequency %) rhea.…”

“…In Brazil, frequencies of rotavirus infection between 20-70% have been reported especially in younger children (Santos et al 2002, Luz et al 2005, Carvalho-Costa et al 2006.…”