Frequency of Strongyloides stercoralis Infection in Alcoholics

Strongyloides ratti antigenic components recognized by IgE antibodies in immunoblotting as an additional tool for improving the immunodiagnosis in human strongyloidiasis

“…Strongyloidiasis is a severe disease, but it can be clinically inapparent in the majority of patients with infection restricted to the gastrointestinal tract. Nevertheless, the systemic invasion of the parasite by its larval stage leads to a fatal hyperinfection syndrome or disseminated strongyloidiasis, particularly in immunocompromised subjects like patients with cancer, organ transplant recipients, acquired immunodeficiency syndrome (AIDS), and patients upon corticoids and other immunosuppressive therapy (Ferreira et al 1999, Siddiqui & Berk 2001, Oliveira et al 2002.…”

Strongyloides Stercoralis Hyperinfection in a Post-Renal Transplant Patient

“…This is seen in certain conditions associated with a decrease in host immunity, including immunosuppressive therapy (particularly the use of glucocorticoids), hematological malignancies, bone marrow and renal transplants, human T-cell lymphotropic virus type 1 infection, human immunodeficiency virus infection, hypogammaglobulinemia, and malnutrition. [5][6][7][8][9][10][11][12][13][14][15][16][17][18] Although various immunocompromising conditions have been associated with hyperinfection, steroids and human T-cell lymphotropic virus type 1 infection are the most consistent. In these conditions S. stercoralis causes hyperinfection.…”

“…Strongyloides infection, in contrast, has been described in a variety of conditions including those on immunosuppressant therapy, post-transplantation, hematologic malignant disease, human immunodeficiency virus, malnutrition, diabetes mellitus, rheumatoid arthritis, chronic renal failure, hypogammaglobulinemia, and chronic alcohol consumption. [5][6][7][8][9][10][11][12][13][14][15][16][17][18] In these patients, hyperinfection can occur, which, if not recognized and treated aggressively, can result in mortality rates as high as 87%. 1,19 In humans, S. stercoralis infestation most commonly involves the upper small intestine and the usual clinical presentation is nonspecific and vague and the infestation can mimic several other conditions such as inflammatory bowel disease.…”

Características clínico-epidemiológicas de la estrongiloidiasis en pacientes portadores de co-morbilidades

“…Algunos estudios sugieren que el etilismo crónico es un importante factor de riesgo para el desarrollo de estrongiloidiasis 30,31 . Estudios realizados por Oliveira y cols., demostraron frecuencias de 33,3 y 5,5% de estrongiloidiasis en pacientes alcohólicos y no alcohólicos, respectivamente 30 .…”

“…Estudios realizados por Oliveira y cols., demostraron frecuencias de 33,3 y 5,5% de estrongiloidiasis en pacientes alcohólicos y no alcohólicos, respectivamente 30 . Marques y cols., evaluaron 263 pacientes consumidores crónicos de alcohol, identificando una tasa de infección de 20,5% mientras en 590 individuos no alcohólicos, tan sólo 4,4% resultaron positivos 32 .…”