Typing and susceptibility to penicillin of Neisseria meningitidis isolated from patients in Cuba (1993-1999)

Sosa, Jorge; Llanes, Rafael; Guzmán, Daymi; Quintana, Ibrahin; Flores, Mayra; Gutiérrez, Óscar

doi:10.1590/s0074-02762001000400014

Cited by 11 publications

(6 citation statements)

References 9 publications

(6 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…P1. 19.15 has been the most frequently identified, using ELISA [ 14 ]. It is likely due to the fact that VA-MEMGOC B-C prevents the disease, but does not eliminate the nasopharyngeal carriage [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

"Bacterial Meningitis in children and adolescents: an observational study based on the national surveillance system"

Dickinson

Pérez

2005

BMC Infect Dis

View full text Add to dashboard Cite

Background: Bacterial meningitis is a group of life threatening infections that mostly affect children and adolescents, and may be the cause of severe neurological sequelae. Cuba has implemented massive vaccination programmes against both Neisseria meningitidis (serogroup C in 1979 and B in 1987), and Haemophilus influenzae type b (1999), two of the main causal pathogens. We described and discussed some epidemiological aspects of the current status of bacterial meningitis to learn from the Cuban experience.

show abstract

Section: Discussionmentioning

confidence: 99%

"Bacterial Meningitis in children and adolescents: an observational study based on the national surveillance system"

Dickinson

Pérez

2005

BMC Infect Dis

View full text Add to dashboard Cite

show abstract

“…Those studies that are available indicate that serogroup B was the most prevalent endemic disease serogroup pre-2000 in several countries in Latin America, including Colombia (78% of isolates identified between 1994 and 2006) [39], Chile (over 90% of isolates identified between 1992 and 1993) [40], Brazil [21] and Uruguay [19, 41]. However, although the incidence of MD in Cuba after the introduction of vaccination remained at <1·4 cases/100 000 population per year from 1992 onwards, a sample of 111 isolates tested from subsequent years indicated that serogroup B, particularly the B:4:P1.15 serotype, remained the dominant cause of disease [32]. …”

Section: Introductionmentioning

confidence: 99%

“…This clone was associated with epidemic disease in Cuba, with a peak incidence of 14 cases/100 000 reported in 1983 [31]. The most prevalent strain in this outbreak was B:4:P1.19,15:L3,7,9, belonging to the ET5 type [32]. This strain was also important in epidemics in Brazil in the late 1980s [33, 34], and was identified as dominant in Brazil in the 1990s [35].…”

Section: Introductionmentioning

confidence: 99%

The epidemiology of meningococcal disease in Latin America 1945–2010: an unpredictable and changing landscape

Sáfadi

Gonzalez-Ayala

Jäkel³

et al. 2012

Epidemiol. Infect.

View full text Add to dashboard Cite

SUMMARYMeningococcal disease is mostly endemic in Latin America, with periodic occurrences of outbreaks and epidemics over the last few decades. This literature review summarizes the available epidemiological data for this region between 1945 and 2010. Incidence rates and serogroup distribution differ from country to country and over time. Serogroups A, B, and C have all been major causes of meningococcal disease since the 1970s. In the last decade serogroups W135 and Y may now be emerging in certain countries, with serogroup A virtually disappearing. Although progress has been made in improving and coordinating the surveillance of invasive disease, the uniformity and quality of reported data reflect the fact that the current surveillance systems focus on passive rather than active reporting, hence the reliability of data may vary between countries. Consideration of vaccination policies to control meningococcal disease can only be made with a sufficient understanding of the changing epidemiology in the region.

show abstract

“…Among the other countries of Latin America, serogroup B has been predominant in Argentina [85] since 2001 and especially during the periods 1993-1995 and 2002-2005, causing about two-third of cases of infections [86], and in Colombia as resulted by the analysis performed on 434 isolates collected between 1994 and 2006 [87]. However, no data on meningitis epidemiology are available for this last country [10] and Cuba, which in 1983 experienced an outbreak caused by serogroup B wherein meningococcal disease reached the incidence of 14.4 cases per 100,000 population [88].…”

Section: Latin Americamentioning

confidence: 99%

Neisseria meningitidisinfection: who, when and where?

Gianchecchi

Torelli

Piccini

et al. 2015

Expert Review of Anti-infective Therapy

View full text Add to dashboard Cite

Neisseria meningitidis is a Gram-negative β-proteobacterium responsible for an endemic worldwide infection. The epidemiology and serogroup distribution can change very quickly. The incidence of meningitis infection varies from very rare to more than 1000 cases per 100,000 of the population yearly. The carriage of N. meningitidis, which represents an exclusive human commensal, is asymptomatic, but in rare cases bacteria proliferate in the CNS and rapidly lead to the death of the affected subjects. Host genetic factors, such as single nucleotide polymorphisms, can promote meningococcal disease, being able to influence the individual predisposition to the pathology. Although a reduction in meningococcal disease has been observed in Europe, a continuous surveillance is necessary to control any possible outbreaks of new hypervirulent clones into populations that could modify the epidemiology of meningococcal infections and the clinical spectrum of affected subjects.

show abstract

Typing and susceptibility to penicillin of Neisseria meningitidis isolated from patients in Cuba (1993-1999)

Cited by 11 publications

References 9 publications

"Bacterial Meningitis in children and adolescents: an observational study based on the national surveillance system"

"Bacterial Meningitis in children and adolescents: an observational study based on the national surveillance system"

The epidemiology of meningococcal disease in Latin America 1945–2010: an unpredictable and changing landscape

Neisseria meningitidisinfection: who, when and where?

Contact Info

Product

Resources

About