Expression of mosquito active toxin genes by a Colombian native strain of the gram-negative bacterium Asticcacaulis excentricus

Treatment of an Aedes aegypti colony with the Cry11Aa toxin for 54 generations results in the development of resistance

“…Alternatives have been proposed to overcome this problem, such as the development of live recombinant algae or bacteria that express toxin(s) and remain within the feeding range of mosquito larvae (Romero et al 2001, Khasdan et al 2003, Zheng et al 2007). However, an important concern raised against this approach is the high risk of the development of resistance by the target insects as resistance to individual B. thuringiensis serovar israelensis toxins has been observed in laboratory colonies of Cx.…”