Retrospective Study on Dengue in Fortaleza, State of Ceará, Brazil

Cunha, Rivaldo Venâncio da; Miagostovich, Marize Pereira; Petrola, Z.; Araújo, Eliane Saraiva Machado de; Cortez, Diógenes Aparı́cio Garcia; Pombo, V.; Souza, Rogério Valls de; Nogueira, Rita Maria Ribeiro; Schatzmayr, Hermann G.

doi:10.1590/s0074-02761998000200003

Cited by 10 publications

(10 citation statements)

References 11 publications

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“…An increase in DHF was observed in 2003, when 23 796 dengue cases were reported, including 291 DHF cases and 20 deaths. This scenario was also observed in 2005 with 22 817 cases reported, including 195 DHF cases and 20 deaths (13)(14)(15)(16).…”

Section: Dengue Viruses In Other Brazilian Statesmentioning

confidence: 66%

Dengue viruses in Brazil, 1986-2006

Nogueira¹,

Araújo²,

Schatzmayr³

2007

Rev Panam Salud Publica

107

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A total of 4,243,049 dengue cases have been reported in Brazil between 1981 and 2006, including 5,817 cases of dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS) and a total of 338 fatal cases. Although all Brazilian regions have been affected, the Northeast and Southeast regions have registered the highest number of notifications. DENV-1 and DENV-4 were isolated for the first time in the Amazon region of Brazil in 1981 and 1982. The disease became a nationwide public health problem following outbreaks of DENV-1 and DENV-2 in the state of Rio de Janeiro in 1986 and 1990, respectively. The introduction of DENV-3 in 2000, also in the state of Rio de Janeiro, led to a severe epidemic with 288 245 reported dengue cases, including 91 deaths. Virus strains that were typed during the 2002 epidemic show that DENV-3 has displaced other dengue virus serotypes and entered new areas, a finding that warrants closer evaluation. Unusual clinical symptoms, including central nervous system involvement, have been observed in dengue patients in at least three regions of the country.

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Section: Dengue Viruses In Other Brazilian Statesmentioning

confidence: 66%

Dengue viruses in Brazil, 1986-2006

Nogueira¹,

Araújo²,

Schatzmayr³

2007

Rev Panam Salud Publica

107

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“…To the best of our knowledge this is the first such study from India. Other workers from abroad, however, have conducted somewhat similar studies [10][11][12][13]. The strengths of this study are the prospective, unbiased enrollment and standardized work up over a complete 1-year period.…”

Section: Discussionmentioning

confidence: 94%

“…Therefore the prevalence of dengue infection as a cause of AUFI was atleast 15/298, i.e., 5.0% as DF could not be ruled out among those tested early during the illness who were IgM negative or in those in whom PCR was not done. Previous workers have found serological positivity ranging from 5.4% to 24% among febrile illness [10][11][12][13].…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Clinical Differentiation of Dengue Fever in Children in Northern India

Kumar

Tripathi

et al. 2008

Infection

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Dengue transmission occurs round the year in this region. The cause of AUFI was definitely dengue in 15/298, i.e., 5% cases and likely to be dengue in another 13.8% cases. In children presenting to outpatients here with AUFI, young age, rash, and raised sALT are significant independent pointers to dengue. A combination of clinical and laboratory features including liver enzymes could be used to achieve high sensitivity and specificity. These results should be validated in a separate data set.

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“…The State of Ceará, in northeastern Brazil, is one of the most important areas in terms of numbers of reported cases of dengue and DHF 5 . The first epidemic in Ceará began in August 1986, and continued until november 1987, with 26,938 cases with laboratory confirmation 6 .…”

Section: Palavras-chavesmentioning

confidence: 99%

Clinical and epidemiological characterization of dengue hemorrhagic fever cases in northeastern, Brazil

Cavalcanti

Coêlho

Vilar

et al. 2010

Rev. Soc. Bras. Med. Trop.

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Introduction:The dengue hemorrhagic dengue (DHF) remains an important public health problem in Brazil. The objective of this study was to analyze the epidemiological characteristics of DHF cases during the 2003 epidemic in Ceará. Methods: Suspected DHF cases with onset of symptoms between January and December 2003 were investigated. Results: 37,964 classic dengue cases and 291 DHF cases were reported. Among the cases discarded, 75.5% were serologically positive but did not meet the criteria recommended by the World Health Organization (WHO). The DHF patients' median age was 30 years (2 -88). Among the hemorrhagic manifestations, petechiae were the most (32.6%) frequent. Cases of gastrointestinal bleeding, ascites, pericardial pleural effusion, hepatomegaly, hypotension and shock showed higher risk of progression to death (p <0.05). Conclusions: The introduction of a new serotype (DEnV-3) in Ceará, which encountered a susceptible population and high vector density, may have been the primary agent responsible for the magnitude of the epidemic. Timely and appropriate medical care, along with an organized care structure are essential for reducing its lethality.

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Retrospective Study on Dengue in Fortaleza, State of Ceará, Brazil

Abstract: A retrospective serologic study was carried out in Fortaleza, State of Ceará, Brazil, in

Cited by 10 publications

References 11 publications

Dengue viruses in Brazil, 1986-2006

Dengue viruses in Brazil, 1986-2006

Prevalence and Clinical Differentiation of Dengue Fever in Children in Northern India

Clinical and epidemiological characterization of dengue hemorrhagic fever cases in northeastern, Brazil

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