Dengue haemorrhagic fever/dengue shock syndrome (DHF/DSS) caused by serotype 2 in Brazil

Dengue situation in Brazil by year 2000

“…Due to lack of funds to maintain the campaign and the emergence of other priorities along the years, the mosquito was reintroduced through the region, from the infested countries and in 1995, and the distribution of Ae. aegypti reached the same level as before the eradication campaign (Gubler 1997 (Nogueira et al 1990, 1991, Miagostovich et al 1993.…”

The History of Dengue Outbreaks in the Americas

“…99,100 The DENV-2 spread to other parts of Brazil with more severe clinical presentations, and the first fatal cases caused by secondary dengue infections. [101][102][103][104] Of interest, an epidemic caused by DENV-2, with the same genotype as the strain that was present before 1981, occurred in the Amazonian region of Peru in 1995 however no DHF cases were reported. 105 The DENV-3, genotype III, virus was reintroduced in the Americas in 1994 initially reported in Nicaragua and Panama.…”

Estudo retrospectivo (histórico) da dengue no Brasil: características regionais e dinâmicas

“…Após um silêncio epidemiológico, o sorotipo DEN-1 invadiu o Sudeste (Rio de Janeiro) e Nordeste (Alagoas, Ceará, Pernambuco, Bahia, Minas Gerais) em 1986-1987 2 17 , espalhando pelo país desde então, com as entradas dos sorotipos DEN-2 em 1990-1991 13 , e o DEN-3 em 2001-2002 12 . No momento, estes três sorotipos circulam simultaneamente em 24 estados da Federação 18 , contribuindo para a incidência das formas graves da dengue (dengue hemorrágica e síndrome do choque da dengue) nas cidades onde se registraram epidemias sequenciais por pelo menos dois sorotipos diferentes 5 , embora a virulência da cepa epidêmica possa ser algumas vezes o determinante principal das formas hemorrágicas 10 16 20 .…”