Experimental canine mucocutaneous leishmaniasis (Leishmania braziliensis braziliensis)

Abstract

Four mongrel dogs were intradermically inoculated with 3 x 10(6) Leishmania braziliensis braziliensis promastigotes. Three out of the four animals developed cutaneous lesions respectively 4, 7, and 8 months after. The fourth dog did not develop lesion at the inoculation site, but a mucosal ulcer was seen 16 months after the inoculum. Clinical, histopathological, and serological findings were similar to what is found in natural canine infection as well as in the human disease. These results suggest that dogs may be an useful model for L. b. braziliensis infection.

An Epidemic Outbreak of Canine Cutaneous Leishmaniasis in Colombia Caused by Leishmania braziliensis and Leishmania panamensis

“…These results differ from those observed by Pirmez and others 23 in dogs naturally infected with L. braziliensis where the majority of the dogs had ulcerated single lesions on the ears. Fifty-nine dogs in total (82%) had a diagnosis of CL by parasitological, serological, or both methods.…”

“…Although L. braziliensis has been involved in canine CL, 14,23,24 this is the first report of L. panamensis affecting dogs. Canine CL is not a frequent event.…”

Aspectos epidemiológicos da leishmaniose tegumentar americana em cães, no Município de Paraty, Estado do Rio de Janeiro, Brasil

“…As lesões sugestivas localizavam-se no pavilhão auricular (dois casos), focinho (um caso), bolsa escrotal (dois casos). Todas as lesões eram ulceradas, únicas e úmidas, compatíveis com as características descritas para as lesões causadas por parasitos pertencentes ao complexo Leishmania braziliensis (Pirmez et al, 1988b). Dos cinco cães que apresentaram lesões sugestivas de LTA, obtivemos isolamento primá-rio de formas promastigotas de Leishmania sp.…”

Leishmania (Viannia) braziliensis em cães naturalmente infectados

“…Tal fato também foi observado por Bray 1 em humanos. Pirmez et al 14 , empregando a IFI em cães experimentalmente infectados na região da mucosa, demonstraram títulos superiores aos encontrados neste estudo. O cão nº 6, apesar de também ter apresentado mais que uma lesão de grande extensão, demonstrou fraca reatividade nos mesmos testes.…”