Pesquisa de anticorpos para arbovírus no soro de residentes no povoado de Corte de Pedra, Valença, Bahia

Abstract

A serological survey for research on antibodies to arbovirus was carried out on 288 residents of the rural zone of the village of Corte de Pedra, Valença, Bahia. It was observed that 3.8% of the sample population presented HI and N antibodies against Flaviviruses (Ilhéus 6, St. Louis 2, Yellow fever 3 and Rocio 1). One person, who had previously lived in the Amazon region, had antibodies to Mayaro. The authors were unable to detect either N antibodies for Piry virus in a random sample of 75 persons or CF antibodies against viruses of the Changuinola and Phlebotomus groups and ungrouped BE AR 408005 and BE AR 421710 in another random sample of 28 individuals. Complementary studies should be conducted in order to define the transmission of the different viruses in the area.

Mayaro virus: the jungle flu

“…An investigation in Valença, Bahia, in the coastal area of Brazil, reported that only one subject (who had a previous residence of 3 years in the Amazonian rainforest) among 288 sampled individuals had antibodies against Mayaro. 54 This subject reported that during his residence in the Amazonian rainforest, he had developed a febrile disease with exanthema and arthralgias. 54 Serological surveys of other populations in northern South America have found antibodies against MAYV in rates that range from 1% to 60%.…”

“…54 This subject reported that during his residence in the Amazonian rainforest, he had developed a febrile disease with exanthema and arthralgias. 54 Serological surveys of other populations in northern South America have found antibodies against MAYV in rates that range from 1% to 60%. 44,55 A study carried out in Belterra, Brazil, between 1977 and 1978 showed that 10.3% of the 161 people tested had antibodies against MAYV.…”

Estado imune contra o vírus vacinal (17D) da febre amarela em duas populações do Estado da Bahia

“…No Brasil, o programa de vacinação com o vírus 17D foi aplicado até o início dos anos 60 em grande número de populações do território nacional 12 , inclusive do Estado da Bahia 21 . A partir da década de 70, esse programa de vacinação ficou quase que restrito aos moradores, viajantes e trabalhadores das regiões Norte e Centro-Oeste do país, áreas endêmicas da febre amarela silvestre.…”

Comparação de dois testes de neutralização, utilizados no diagnóstico sorológico do vesiculovírus Piry

“…Precocemente na infecção aguda, e de forma marcante na fase de convalescença, aparecem os anticorpos neutralizantes, os quais permanecem por longos períodos ou por toda a vida 9 . No Brasil, a freqüência dos indivíduos com anticorpos neutralizantes anti-Piry varia de 0 a 40,2% 8,11,25,31,32 . Em indivíduos adultos de Catolândia-Bahia, em estudo sorológico preliminar, a freqüência dos anticorpos neutralizantes anti-Piry foi de 33,3% 33 , detectados pelo teste de neutralização em camundongos (TN-camundongos).…”