O centenário de Carlos Chagas e a menina Berenice

Salgado, J. A.

doi:10.1590/s0074-02761980000100020

Cited by 9 publications

(6 citation statements)

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“…CHD was identified by Carlos Chagas in 1922 20 , and the IF of the disease was identified only years later. Curiously, the first case described in the literature (in a child called Berenice) was configured over the years as IF, and the patient died at 72 years of age without signs of heart disease 21 . The studies published in the first decades indicated that the IF was a transitory stage, wherein all individuals would have the potential to progress to CHD 22 .…”

Section: History and Conceptmentioning

confidence: 99%

Indeterminate form of Chagas disease: historical, conceptual, clinical, and prognostic aspects

Hasslocher‐Moreno

Xavier

Saraiva

et al. 2021

Rev. Soc. Bras. Med. Trop.

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Chagas disease (CD) remains a serious endemic disease in Latin America and a major public health problem. Because of globalization, the disease has spread to non-endemic areas in the northern hemisphere. In the chronic phase of the disease, most patients present with the indeterminate form (IF), characterized by positive serology for Trypanosoma cruzi, absence of clinical findings, and normal findings in electrocardiogram (ECG). IF was not recognized as a clinical entity until decades after the discovery of the disease, and only in the 1940-50s, it was categorized as a form of CD, and its conceptual definition was ratified in the 1980s. Children, adolescents, and young adults with the IF benefit from etiological treatment and tend to have less progression to heart disease in the long term than the untreated ones. IF patients have an essentially benign clinical condition, and their prognosis can be compared to that of healthy individuals with normal ECG findings. Currently, because of aging, patients with the IF have comorbidities that require attention in health services.

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Section: History and Conceptmentioning

confidence: 99%

Indeterminate form of Chagas disease: historical, conceptual, clinical, and prognostic aspects

Hasslocher‐Moreno

Xavier

Saraiva

et al. 2021

Rev. Soc. Bras. Med. Trop.

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“…She also mentioned that he had proposed taking her to be educated in Rio de Janeiro, but her parents had been opposed to the idea. Berenice died of heart failure in 1981 at seventy-three years of age (Salgado, 1980). 12 The first nomination for the Nobel prize was made by the physician and researcher Manuel Augusto Pirajá da Silva from the state of Bahia.…”

Section: Final Considerationsmentioning

confidence: 99%

The discovery of Trypanosoma cruzi and Chagas disease (1908-1909): tropical medicine in Brazil

Kropf

Sá

2009

Hist. cienc. saude-Manguinhos

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This article analyzes the discovery of Chagas disease and the parasite that causes it (Trypanosoma cruzi) by Carlos Chagas in 1908/1909, with a special focus on the scientific and social context in which this occurred. Its inclusion in the international debate on European tropical medicine - especially with researchers from the German school of protozoology - and its connection with discussions on the modernization of the recently established Brazilian Republic are also examined. The discovery of Chagas disease became a decisive aspect in the scientific project that Oswaldo Cruz sought to establish at the institute that bears his name. It was extolled as a symbol of Brazil's scientific ability to produce knowledge in line with the international scientific agenda, while simultaneously being attuned to the specific problems of the country.

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“…Berenice, a criança na qual Chagas detectou e descreveu a doença aguda pela primeira vez, em 1909, estava viva 70 anos depois (Salgado, 1980) …”

Section: José Rodrigues Couraunclassified

Clínica e terapêutica da doença de Chagas: uma abordagem prática para o clínico geral

Dias¹,

Coura²

1997

118

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O centenário de Carlos Chagas e a menina Berenice

Cited by 9 publications

References 0 publications

Indeterminate form of Chagas disease: historical, conceptual, clinical, and prognostic aspects

Indeterminate form of Chagas disease: historical, conceptual, clinical, and prognostic aspects

The discovery of Trypanosoma cruzi and Chagas disease (1908-1909): tropical medicine in Brazil

Clínica e terapêutica da doença de Chagas: uma abordagem prática para o clínico geral

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