Pesquizas sobre o Granuloma venereo

Aragão, Henrique de Beaurepaire; Vianna, Gaspar

doi:10.1590/s0074-02761913000200006

Cited by 37 publications

(14 citation statements)

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“…When they are roundcoccus, they measure between 1 to 2.5 µms in length. Aragão and Vianna [3] were the first authors to classify the agent of donovanosis, Calymmatobacterium granulomatis.…”

Section: Etiologymentioning

confidence: 99%

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Donovanosis

Velho¹,

Souza²,

Belda³

2008

Braz J Infect Dis

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Donovanosis is a chronic bacterial illness frequently associated with sexually transmitted infections (STI) and is under diagnosed both in endemic areas as well as in countries in which doctors have little experience with tropical diseases. The utilization of syndromic diagnosis and treatment of STIs in various parts of the world and the previous use of antibiotics make it difficult to find Donovan bodies in the cytodiagnostic and hystopathological exams, requiring the utilization of technology that is neither routine nor often accessible to confirm the hypothesized diagnosis. Therefore, it is necessary to bring medical professionals up to date about this infectious disease.

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Section: Etiologymentioning

confidence: 99%

“…After the introduction of emetic tartar by Aragão and Vianna in 1913, and with the advent of antibiotics and the discovery of the bacterial etiology of donovanosis, various substances have been employed in the treatment of this illness, with better results and fewer side effects than with antimonials.…”

Section: Who (2003)mentioning

confidence: 99%

Donovanosis

Velho¹,

Souza²,

Belda³

2008

Braz J Infect Dis

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“…Aragao and Viana proposed the name Calymmatobacterium granulomatis in 1913 after the Greek word kalymma, which means hood. 34 They also first treated granuloma inguinale with antimony, but good clinical results were associated with severe side effects. In 1939, Greenblatt inoculated the pus from a pseudobubo of a patient with granuloma inguinale into a volunteer, obtaining in the resulting lesion a demonstration of the organism.…”

Section: Granuloma Inguinalementioning

confidence: 99%

Tropical dermatology: Bacterial tropical diseases

Lupi

Madkan

Tyring

2006

Journal of the American Academy of Dermatology

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“…The causative organism was originally classi® ed as C. granulomatis in 1913 19 . Although Anderson suggested a change to Donovania granulomatis 20 , the original name has persisted.…”

Section: Classification Of the Causative Organismmentioning

confidence: 99%

Donovanosis: an update

O’Farrell

2001

Int J STD AIDS

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Donovanosis has been ignored for many years until recently. The condition still has a limited geographical distribution. A significant epidemic of donovanosis has been identified in KwaZulu/Natal, South Africa where it may be a risk factor for acquiring HIV in men. After a gap of more than 30 years, the organism was cultured by researchers in Durban, South Africa and Darwin, Australia. Polymerase chain reaction (PCR) techniques for donovanosis were developed soon after, most recently using a colorimetric detection system. Similarities between the causative organism, Calymmatobacterium granulomatis and Klebsiella spp. were confirmed. A proposal that the organism be reclassified under the genus Klebsiella has been put forward. Azithromycin has been confirmed as the drug of choice but is yet to be accepted universally because of cost issues. Treatment in patients with significant HIV induced immune deficiency may need to be prolonged. A donovanosis eradication programme is underway amongst the aboriginal community in Australia. Elsewhere, management through current syndromic guidelines for genital ulcers are yet to be validated in areas where donovanosis is endemic. PCR testing should enable further recognition of donovanosis and lead to more concerted efforts in disease control and possible eradication.

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Pesquizas sobre o Granuloma venereo

Cited by 37 publications

References 0 publications

Donovanosis

Donovanosis

Tropical dermatology: Bacterial tropical diseases

Donovanosis: an update

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