Estudos sobre Alastrim

Aragão, Henrique de Beaurepaire

doi:10.1590/s0074-02761911000200007

Cited by 8 publications

(2 citation statements)

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“…Ruediger, quoted by Ashburn et at. (1913), passed the virus from a fatal case of small-pox in 1908 through two monkeys, from the second monkey to a heifer, and after five successive passages through heifers on to man.…”

Section: The Experimental Transformation Ofmentioning

confidence: 98%

“…For a short series of passages the virus can be kept going from dermis to dermis, but attempts to secure good surface takes on the scarified skin of the rabbit with dermal material generally failed." Aragao (1911), using a mixture of material from various cases of alastrim, inoculated five young calves and numerous rabbits but failed to secure a take by scarification on the shaved skin of the animals. Successive corneal passages on the rabbit and intradermal injection of rabbits with material from corneas infected with alastrim were equally unsatisfactory.…”

Section: The Experimental Transformation Ofmentioning

confidence: 99%

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The experimental transformation of variola to vaccinia

Horgan

1938

Epidemiol. Infect.

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1. The more recent literature on the experimental methods employed in variola or alastrim-vaccinia variation is reviewed and briefly discussed.2. An account is given of attempts to produce a vaccinia variant from variola of the virulent type and a successful result, by employing the method of intratesticular passage, has been described.3. The reasons for accepting this as a genuine variation and not a vaccinial contamination are discussed.4. An attempt has been made to analyse some possible factors underlying the discrepancies in the literature, and a plea is made for more co-operation in future work on the subject.

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Section: The Experimental Transformation Ofmentioning

confidence: 98%

Section: The Experimental Transformation Ofmentioning

confidence: 99%