Avaliação da função sistólica longitudinal na insuficiência cardíaca com fração de ejeção normal

Jorge, Antônio José Lagoeiro; Silva, Eduardo Nani da; Fernandes, Luíz Cláudio; Ribeiro, Mário Luiz; Mesquita, Evandro Tinoco; Licio, Fernanda Volponi

doi:10.1590/s0066-782x2010005000050

Cited by 4 publications

(1 citation statement)

References 23 publications

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“…Systolic myocardial velocity (S′) at the lateral mitral annulus is a measure of longitudinal systolic function 13. Jorge et al31 observed a reduced contractility in the longitudinal axis in patients with suspected HFpEF, and found a linear correlation between the systolic subendocardial dysfunction (S′) and the diastolic abnormalities (E/e′, e′). In the PARAMOUNT trial, mitral S′ velocities were lower in women than in men, but no sex-specific differences were found in deformation imaging parameters.…”

Section: Discussionmentioning

confidence: 99%

Sex-specific predictors of left ventricular diastolic dysfunction in untreated hypertension

Jaroch¹,

Vriz²,

Bociąga³

et al. 2016

CIA

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BackgroundLittle is known about the sex-specific differences in left ventricular (LV) diastolic dysfunction (DD) predictors. We hypothesized that arterial stiffness (AS) may play a different role in the etiology of LV DD in hypertensive men and postmenopausal women, acting independently from other established predictors of this condition, such as age, obesity, diabetes mellitus, LV remodeling, and systolic function.ObjectivesThe aim of the study was to analyze the sex-specific differences in AS and other predictors of LV DD in men and postmenopausal women with untreated hypertension (HTN).Patients and methodsThe study included 144 patients (63 postmenopausal women and 81 men, mean age 62.7±6.7 years) with previously untreated HTN and no history of cardiovascular diseases. All patients were subjected to detailed echocardiography, vascular ultrasound, and high-resolution echotracking (eTracking) of carotid arteries.ResultsIn the multivariate analysis, concomitant diabetes mellitus turned out to be an independent predictor of LV DD in women (P=0.02). In turn, two independent predictors of LV DD have been identified in men: S′-tissue Doppler-derived peak LV longitudinal systolic shortening velocity (P=0.001) and β, beta stiffness index (P=0.004).ConclusionThere are sex differences in the predictors of LV DD in untreated HTN. In postmenopausal women, LV DD is mostly determined by diabetes, while in men, it is determined by S′, reflecting LV systolic longitudinal function, and β, a parameter of AS.

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Section: Discussionmentioning

confidence: 99%

Sex-specific predictors of left ventricular diastolic dysfunction in untreated hypertension

Jaroch¹,

Vriz²,

Bociąga³

et al. 2016

CIA

View full text Add to dashboard Cite

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Heart failure with normal left ventricular ejection fraction

Hayley

Burwash

2012

Current Opinion in Cardiology

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Update on diastolic heart failure or heart failure with preserved ejection fraction in the older adults

et al. 2012

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Nearly half of all heart failure (HF) patients have diastolic HF (DHF) or clinical HF with normal or near-normal left ventricular ejection fraction (LVEF). Although the terminology has not been clearly defined, it is increasingly being referred to as HF with preserved ejection fraction (HFPEF). The prevalence of HFPEF increases with age, especially among older women. Identifying HFPEF is important because the etiology, pathogenesis, prognosis, and optimal management may differ from that for systolic HF (SHF) or HF with reduced ejection fraction. The clinical presentation of HF is similar for both SHF and HFPEF. As in SHF, HFPEF is a clinical diagnosis. Once a clinical diagnosis of HF has been made, the presence of HFPEF can be established by confirming a normal or near-normal LVEF, often by an echocardiogram. HFPEF is often associated with a history of hypertension, concentric left ventricular hypertrophy, vascular stiffness, and left ventricular diastolic dysfunction. As in SHF, HFPEF is also associated with poor outcomes. While therapies with angiotensin-converting enzyme inhibitors and beta-blockers improve outcomes in SHF, there is currently no such evidence of their benefits in older HFPEF patients. In this review recent advances in the diagnosis and management of HFPEF in older adults are discussed.

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Avaliação da função sistólica longitudinal na insuficiência cardíaca com fração de ejeção normal

Cited by 4 publications

References 23 publications

Sex-specific predictors of left ventricular diastolic dysfunction in untreated hypertension

Sex-specific predictors of left ventricular diastolic dysfunction in untreated hypertension

Heart failure with normal left ventricular ejection fraction

Update on diastolic heart failure or heart failure with preserved ejection fraction in the older adults

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