QRS Voltage-Duration Product in the Identification of Left Ventricular Hypertrophy in Spontaneously Hypertensive Rats

Abstract

LVM was not the major determinant of QRS voltage changes and consequently of the VDP. These data point to the importance of the nonspatial determinants of the recorded QRS voltage in terms of the solid angle theory.

Old spontaneously hypertensive rats gather together typical features of human chronic left-ventricular dysfunction with preserved ejection fraction

“…To verify this hypothesis, we performed ECG just before LV catheterization at the end of our study. We confirmed previous data showing intracardiac conduction abnormalities, such as PR prolongation and QRS enlargement [34,35]. The last could also be due to both cardiac hypertrophy and interstitial fibrosis.…”

Body Surface Potential Mapping in Hypertensive Rat During Ventricular Depolarization

“…Нет единодушного мнения по поводу изменения длительности комплекса QRS на ЭКГ у крыс SHR. Одни авторы показали, что удлинение QRS начинается с трехмесячного возраста и значительно увеличивается к двенадцати месяцам постнатального развития.Другие авторы, напротив, показали статистически значимые отличия в длительности QRS только у старых (> 76 недель) крыс линии SHR[14].…”