Salivary gland tumors in a Brazilian population: a retrospective study of 124 cases

Abstract

Patients with benign and malignant tumors presented with a mean age of 47.7 and 48.8 years, respectively. The frequency of benign tumors was 80% (n = 99) and malignant tumors 20% (n = 25). Tumors were localized in the parotid gland 71% (n = 88), in the submandibular gland 24% (n = 30), and in the minor salivary glands 5% (n = 6). The most common benign tumors were pleomorphic adenoma in 84% (n = 84) and Warthin's tumor in 13% (n = 13). Among malignant tumors, mucoepidermoid carcinoma was the most common in 52% (n = 13), adenoid cystic carcinoma occurred in 20% (n = 5), and carcinoma ex pleomorphic adenoma was detected in 12% (n = 3).

Salivary Gland Tumor: A Review of 599 Cases in a Brazilian Population

“…This is in agreement with previously published studies [3,[7][8][9][10][11][12], though other epidemiological studies showed a predominance of less than 60% for benign tumors [13,14]. Worldwide studies show geographic variation in the relative incidence of salivary gland tumors with differences in histological type [2,8].…”

“…Benign tumors affected mostly women, though no statistical difference was observed for sex, in agreement with other epidemiological series [9][10][11]. In the present study, age distribution varied from 1 to 88 years-old, with a median of 45 years of age and a peak incidence from 30 to 39 years of age, as reported by other authors [3,[9][10][11][12][13][14]. The median age for malignant tumors (55 years old) was significantly higher than for benign tumors (43 years old).…”

“…According to other studies [10,12], Warthin's tumor was the third most diagnosed of all salivary gland tumors involving 6.4% of cases, with the majority located in the parotid gland (94.7%). In this work, it was the second most common benign tumor representing 8.2% of cases, as has also been observed in other Brazilian studies [9][10][11]. Malignant tumors represented 21.7% of all salivary gland tumors.…”

“…No case was identified in the sublingual gland, as mentioned in other studies [3,9,10,12]. This confirms the rarity of salivary tumors at this site.…”

Histopathological Diversity in Parotidectomy Materials in Turkish Population: Clinicopathologic Analysis and Demographic Features of 136 Cases in a Tertiary Care Hospital

“…The benign/malign ratios were reported as 78.5/21.5 (Kizil et al, 2013) and 79.5/20.5 (Gunizi and Guney, 2013) in the previous studies. On the other hand the results of researchers outside our country were as follows: in the salivary gland series where 88 had parotid within the Brazilian population (Vargas et al, 2002), they detected 83% benign and 17% malignant parotid tumors. In the 271-patient study conducted in Taiwan (Lin et al, 2008), 85% were benign and 12% were malignant and 3% constituted chronic inflammatory pathologies.…”