Vertical transmission of HIV-1 in the western region of the State of São Paulo

Gonçalves, Vera Lúcia Maria Alves; Troiani, Charlene; Ribeiro, Armênio Alcântara; Spir, Patrícia Rodrigues Naufal; Gushiken, Elza Keiko Kimura; Vieira, Renata Bonfim; Prestes-Carneiro, Luiz Euribel

doi:10.1590/s0037-86822011000100002

Cited by 14 publications

(9 citation statements)

References 17 publications

(13 reference statements)

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“…It is noteworthy that many exposed children still do not have a final diagnosis, which could represent changes in the proportions observed. This problem was present in another study, which showed that 20% of mothers did not know the HIV status of their children up to eight months after delivery 23 .…”

Section: Discussionmentioning

confidence: 96%

Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, State of Sergipe, Brazil

Lemos

Rocha

Conceição

et al. 2012

Rev. Soc. Bras. Med. Trop.

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Introduction:The main route of human immunodeficiency virus (HIV) infection in children is from mother to child. The preventive measures established for the Aids Clinical Trial Group protocol 076 (ACTG 076) significantly reduces HIV vertical transmission rates. This study aims to evaluate the implementation of the ACTG 076 protocol in the maternity units of State of Sergipe, Brazilian northeast. Methods: This is a descriptive, retrospective study with a quantitative approach, with HIV positive women and children exposed, attending a Maternity reference for high-risk pregnancies. Data were obtained from patient records registered in the years 1994 to 2010. Results: Amongst the 110 pregnant women and exposed newborns, the ACTG 076 protocol was fully utilized in only 31.8% of the participants. During the prenatal period, zidovudine (ZDV) was taken by 79.1% of the pregnant women. Only 49.1% of HIV seropositive patients used ZDV during delivery. Two (1.8%) children were considered infected and 50 (45.5%) do not have a conclusive diagnosis to date. Conclusions: There were significant deficiencies in the prevention of mother-to-child transmission of HIV, including lack of compliance with the three phases of the ACTG 076 protocol; inadequacies in prenatal care; inappropriate mode of delivery and lack of adequate follow up of exposed children.

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Section: Discussionmentioning

confidence: 96%

Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, State of Sergipe, Brazil

Lemos

Rocha

Conceição

et al. 2012

Rev. Soc. Bras. Med. Trop.

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“…Brazil was one of the first developing countries to implement measures to prevent mother-to-child transmission (MTCT) of HIV-1, resulting in a decrease in vertical transmission rates (PN-DST/ AIDS, 2006; AMARAL et al, 2007; PRESTES- CARNEIRO et al, 2009). There are limited data addressing the prevalence and risk factors of MTCT in the western region of the São Paulo State (GONÇALVES et al, 2011). A recent study showed a growing AIDS dissemination among females in small-sized municipalities in the state (PRADO & CASTILHO, 2009).…”

Section: Introductionmentioning

confidence: 99%

HIV-1-mother-to-child transmission and associated characteristics in a public maternity unit in Presidente Prudente, Brazil

Prestes-Carneiro

Spir

Ribeiro

et al. 2012

Rev. Inst. Med. trop. S. Paulo

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SUMMARYIn children, vertical transmission is the main form of HIV infection. Our aim was to determine the prevalence of HIV-1 vertical transmission in mother-infant pairs in a public maternity ward in Presidente Prudente, SP. Additionally; we sought to identify characteristics associated with this form of transmission. The files of 86 HIV-1-infected mothers and their newborns referred to a Public Hospital from March 2002 to March 2007 were analyzed. The HIV-1-RNA viral load of the newborns was determined by bDNA. The HIV-1 vertical-transmission rate was 4.6%. Children that were born in the pre-term period and breastfed were at a higher risk of HIV-1 infection (p = 0.005 and p = 0.017 respectively) than children born at term and not breastfed. Prophylactic therapy with zidovudine after birth for newborns was associated with a lower risk of infection (p = 0.003). The number of newborns weighing < 2,500 g was significantly higher for infected children (p = 0.008) than for non-infected newborns. About 22.9% of mothers did not know the HIV-1 status of their newborns eight months after delivery. The study suggests that it is necessary to increase the identification of HIV-1 infection in pregnant women and their newborns as well as to offer and explain the benefits of ARV prophylaxis.

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“…(1) As most infected women are of reproductive age, there is particular interest in prevention of vertical transmission of HIV, which can occur during pregnancy, labor, delivery or breastfeeding. (2) Ensuring an effective preconception care is essential to tackle that problem, aiming at knowing the HIV status of the mother, instructing her and providing preventive care against vertical transmission, a policy that depends on the early identification of infected pregnant women to be successful.…”

Section: Introductionmentioning

confidence: 99%

Grau de conhecimento, atitudes e práticas de puérperas sobre a infecção por HIV e sua prevenção

Brasil¹,

Moreira²,

Teles³

et al. 2014

Acta paul. enferm.

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Objective: Evaluating the level of knowledge, attitudes and practices of puerperal women on HIV infection and its prevention. Methods: A cross-sectional study with 278 puerperal women hospitalized in the rooming-in system. Interviews were carried out with the use of a questionnaire to evaluate the knowledge, attitudes and practices on HIV infection and its prevention. Results: The age of puerperal women ranged from 13 to 43 years, with prevalence of the range between 20 and 34 years. The level of education between eight and 11 years of studies was predominant, as well as the stable union. Only 54 (19.4%) puerperal women showed adequate knowledge, six showed adequate attitude (2.2%) and four showed appropriate practices (1.4%). Conclusion:The knowledge was inadequate due to the low percentage of puerperal women able to mention at least three ways of transmission and three forms of preventing the virus; inadequate attitude was marked by the high percentage of puerperal women who perceive becoming infected with HIV as 'unlikely', and 'little likely' that the same occurs with their partners. The inadequate practice was influenced by the low percentage of HIV testing in the recommended periods and the lack of condom use during pregnancy. ResumoObjetivo: Avaliar o grau de conhecimento, atitudes e práticas de puérperas sobre a infecção por HIV e sua prevenção. Métodos: Estudo transversal com 278 puérperas internadas no sistema de alojamento conjunto. Foram realizadas entrevistas com a utilização de um questionário para avaliar o conhecimento, a atitude e a prática sobre a infecção pelo HIV e sua prevenção. Resultados: A idade das puérperas variou de 13 a 43 anos, prevalecendo faixa entre 20 e 34 anos. Predominou escolaridade entre 8 e 11 anos de estudos e união estável. Apenas 54 (19,4%) puérperas apresentaram conhecimento adequado, 6 (2,2%) atitude e 4 (1,4%) práticas adequadas. Conclusão: O conhecimento foi inadequado devido ao baixo percentual de puérperas que souberam citar pelo menos três formas de transmissão e três formas de prevenção do vírus; a atitude inadequada foi marcada pelo elevado percentual de puérperas que percebem como "improvável" infectar-se com o HIV e "pouco provável" o mesmo ocorrer com seu parceiro. A prática inadequada foi influenciada pelo baixo percentual de realização do teste anti-HIV nos períodos preconizados e pelo não uso do preservativo durante a gravidez.

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Vertical transmission of HIV-1 in the western region of the State of São Paulo

Cited by 14 publications

References 17 publications

Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, State of Sergipe, Brazil

Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, State of Sergipe, Brazil

HIV-1-mother-to-child transmission and associated characteristics in a public maternity unit in Presidente Prudente, Brazil

Grau de conhecimento, atitudes e práticas de puérperas sobre a infecção por HIV e sua prevenção

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