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Amato, Juliane Gomes de Paula; Amato, Valdir Sabbaga; Neto, Vicente Amato; Heins‐Vaccari, Elisabeth Maria

doi:10.1590/s0037-86822002000300014

Cited by 5 publications

(1 citation statement)

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“…. Out of six cases where fungus was upto genus Trichoderma, two cases (case report presented by Venugopal et al(76) and by Amato et al(77) showed no details like patient's age, gender, treatment strategy. Out of remaining four cases, 3 were male and 1 was female; 3 were recovered after treatment and one expired.…”

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confidence: 94%

An in-sight analysis of molecular evolution of Trichoderma as emerging human pathogen

Ghosh

2022

Preprint

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Due to climatic changes, anthropogenic activity and pollution, new variants of known species of human pathogens are emerging. Similarly, non-pathogenic Trichoderma spp are becoming pathogenic via molecular evolution. The literature survey provides us that some spp of Trichoderma (T. longibrachiatum, T. viride, T. koningii, T, harzianum, T. citrinoviride, T. reesii, T. atroviride and T. pseudokoningi) infected some organs of patients which were immune-compromised. These are the case of “cross-kingdom host jumps”. The first case report was found in 1970. Latest case report was presented in 2019. So, after 50 years, 42 cases or episodes of Trichoderma infection to human have been recorded. In maximum cases T. longibrachiatum was involved. Proposed pathogenecity factors, molecular evolution and a hypothetical linage of evolution of clinical Trichoderma have been presented here. Although, this opportunistic pathogen is still not reported in COVID-19 patients, it may infect them as COVID-19 patients are with high risk factors. , .

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confidence: 94%