Infecção pelos vírus linfotrópicos de células T humanas dos tipos I (HTLV-I) e II (HTLV-II) em portadores do HIV em Santos-SP: estudo de prevalência e fatores de risco

Etzel, Arnaldo

doi:10.1590/s0037-86821999000600022

Cited by 3 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[1][2][3][4] HTLV-1 infection is endemic in Brazil and, an estimation by the Ministry of Health 5 states that 750,000 people are carriers of HTLV, with a prevalence varying from 0.4% to 18% depending on the geographic region. [6][7][8][9][10] Psychiatric disorders appear to be common in patients with chronic diseases, as in tropical spastic paraparesis/HTLV-1 associated myelopathy (HAM/TSP). Besides, depression and anxiety symptoms may contribute to progressive disability and limitations in daily living activities impacting their perceptions about quality of life.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of anxiety, depression and quality of life in HTLV-1 infected patients

Gascón¹,

Capitão²,

Casseb³

et al. 2011

Braz J Infect Dis

View full text Add to dashboard Cite

The HAM/TSP caused by HTLV-1 infection usually affects patients to disabling states, and sometimes can lead them to paraplegia presenting symptoms of depression and anxiety, impacting on quality of life. Objective: The purpose of this study was to evaluate the frequency of depression and anxiety and its impact on quality of life in HTLV-1-infected TSP/HAM patients. Material and Methods: This was a cross-sectional study including 67 asymptomatic (control group) and 63 with TSP/HAM subjects. The instruments used were a demographic questionnaire, scales for anxiety and depression diagnosis (BDI and BAI), questionnaire for the assessment of Quality of Life of the World Health Organization (WHOQOL-Brief) and neurological scale to measure the disability level (Osame's Disability Status Scale). All patients had HTLV-I diagnosis by serological and molecular approaches, monitored at Instituto de Infectologia Emílio Ribas from May 2008 to July 2009. Data were analyzed statistically by frequencies, the Mann-Whitney test and the Spearman correlation test. Data among groups were analyzed and correlated with functional and severity aspects. Results: The results showed that patients with HAM/TSP compared to asymptomatic carriers had higher rates of depression (p < 0.001) and anxiety (p < 0.001), and impairment on quality of life in the areas of: dissatisfaction with health (p < 0.001), physical (p < 0.001) and the environment (p = 0.003). The main factors that correlated with levels of depression and anxiety and the domains of the WHOQOL-brief were: education, family income and social class. Conclusion: A well conducted evaluation and counseling may help in treatment, for a better quality of life of these patients.

show abstract

Section: Introductionmentioning

confidence: 99%

Prevalence of anxiety, depression and quality of life in HTLV-1 infected patients

Gascón¹,

Capitão²,

Casseb³

et al. 2011

Braz J Infect Dis

View full text Add to dashboard Cite

show abstract

“…The human T cell lymphotropic virus I and II (HTLV I/II) can be transmitted by blood and cellular blood products, maternal milk, sexual contact and by the shared use of syringes and needles among intravenous drugs abusers 18 . Rates of prevalence of anti-HTLV I/II among patients with acquired immunodeficiency syndrome, homosexual men, HIV infected patients and intravenous drug users are registered 4,18 . In this study, we evaluated the importance of surrogate markers such as anti-HBc, anti-HCV, anti-HTLV I/II antibodies, serologic test for syphilis (STS), and HBsAg for the risk for HIV infection among blood donors.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of surrogate markers for human immunodeficiency virus infection among blood donors at the blood bank of "Hospital Universitário Regional Norte do Paraná", Londrina, PR, Brazil

Reiche

Vogler

Morimoto

et al. 2003

Rev. Inst. Med. trop. S. Paulo

View full text Add to dashboard Cite

This study evaluated the usefulness of the anti-HBc, hepatitis C virus antibodies (anti-HCV), human T cell lymphotropic virus I and II antibodies (anti-HTLV I/II), serologic tests for syphilis, and surface antigen of hepatitis B virus (HBsAg) as surrogate markers for the risk for HIV infection in 80,284 serum samples from blood donors from the Blood Bank of "Hospital Universitário Regional Norte do Paraná", Londrina, Paraná State, Brazil, analyzed from July 1994 to April 2001. Among 39 blood donors with positive serology for HIV, 12 (30.8%) were anti-HBc positive, 10 (25.6%) for anti-HCV, 1 (2.6%) for anti-HTLV I/I, 1 (2.6%) was positive for syphilis, and 1 (2.6%) for HBsAg. Among the donors with negative serology for HIV, these markers were detected in 8,407 (10.5%), 441 (0.5%), 189 (0.2%), 464 (0.6%), and 473 (0.6%) samples, respectively. The difference was statistically significant (p < 0.001) for anti-HBc and anti-HCV. Although the predictive positive values for these surrogate markers were low for HIV infection, the results confirmed the anti-HBc and anti-HCV as useful surrogate markers for HIV infection thus reinforcing the maintenance of them in the screening for blood donors contributing to the prevention of the small number of cases in which HIV is still transmitted by transfusion.

show abstract

Prevalence of anxiety, depression and quality of life in HTLV-1 infected patients

Gascón¹,

Capitão²,

Casseb³

et al. 2011

The Brazilian Journal of Infectious Diseases

View full text Add to dashboard Cite

Infecção pelos vírus linfotrópicos de células T humanas dos tipos I (HTLV-I) e II (HTLV-II) em portadores do HIV em Santos-SP: estudo de prevalência e fatores de risco

Cited by 3 publications

References 0 publications

Prevalence of anxiety, depression and quality of life in HTLV-1 infected patients

Prevalence of anxiety, depression and quality of life in HTLV-1 infected patients

Evaluation of surrogate markers for human immunodeficiency virus infection among blood donors at the blood bank of "Hospital Universitário Regional Norte do Paraná", Londrina, PR, Brazil

Prevalence of anxiety, depression and quality of life in HTLV-1 infected patients

Contact Info

Product

Resources

About