Prevalence of anxiety, depression and quality of life in HTLV-1 infected patients

Gascón, Maria Rita Polo; Capitão, Cláudio Garcia; Casseb, Jorge; Nogueira-Martins, Maria Cezira Fantini; Smid, Jerusa; Oliveira, Augusto César Penalva de

doi:10.1590/s1413-86702011000600013

Cited by 26 publications

(29 citation statements)

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“…The prevalence of depression and anxiety found by Souza et al [ 24 ] and Gascón et al [ 22 ], who investigated through severity scales, was higher than our findings. Such differences seem to be due to the fact that we used the HADS scale, which prioritizes non-somatic symptoms.…”

Section: Discussioncontrasting

confidence: 96%

Psychiatric Disorders in HTLV-1-Infected Individuals with Bladder Symptoms

et al. 2015

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BackgroundPrevious studies have reported high rates of depression and anxiety in HTLV-1 infected individuals with the neurological disease and in the asymptomatic phase. No study has investigated the rates in individuals that already show bladder symptoms without severe neurological changes; that is, during the oligosymptomatic phase. The present study investigated patients in this intermediate form on the spectrum of the infection.Methodology/Principal FindingsParticipants answered a sociodemographic questionnaire, the Mini International Neuropsychiatric Interview Brazilian Version 5.0.0 (MINI PLUS) and the Hospital Anxiety and Depression Scale (HADS). Data analysis was performed in STATA statistical software (version 12.0). Depressive disorder was the most frequent comorbidity. Current depressive disorder was higher in the group of overactive bladder subjects (11.9%), and lifelong depression was more frequent in the HAM/TSP group (35%). The three groups had similar frequencies of anxiety disorders. Increased frequency and severity of anxiety and depression symptoms were observed in the overactive bladder group.Conclusion/SignificanceThe results suggest that individuals with overactive bladders need a more thorough assessment from the mental health perspective. These patients remain an understudied group regarding psychiatric comorbidities.

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Section: Discussioncontrasting

confidence: 96%

Psychiatric Disorders in HTLV-1-Infected Individuals with Bladder Symptoms

et al. 2015

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“…However, even apparently asymptomatic infection has a negative impact on the life of HTLV-1 seropositive patients. Decreased quality of life, increased incidence of depression and anxiety among asymptomatic individuals diagnosed with HTLV infection has been demonstrated and are not necessarily a consequence of being informed of the diagnosis [39–41]. In Brazil, this can be exacerbated by the lack of care in public health that HTLV infected patients need to face as clearly reported by Zihlmann and colleagues (2012) [42].…”

Section: Discussionmentioning

confidence: 99%

Estimation of HTLV-1 vertical transmission cases in Brazil per annum

et al. 2018

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BackgroundBrazil has at least 800,000 HTLV-1 infected individuals. HTLV-1 can be transmitted via sexual intercourse, contact with blood and from mother to child, mainly by breastfeeding. Treatments for the high morbidity/mortality associated diseases (ATL and HAM/TSP) are limited, therefore, infection prevention is of utmost importance. However, antenatal screening is not routinely performed in Brazil. A lack of data regarding the number of individuals infected via breastfeeding impairs the development of government policies. The objective is to estimate the number of HTLV-1 infections occurring annually due to mother to child transmission (MTCT) in Brazil, nationally and regionally.MethodologyTo estimate HTLV-1 MTCT in Brazil the following variables are modelled: number of births, prevalence of HTLV-1 infection in pregnant women, breastfeeding duration rate and transmission risk according to breastfeeding period. The number of cases of HAM/TSP and ATL attributable to MTCT are also estimated.Principal findingsIn 2008, there were 2,934,828 live births in Brazil. HTLV prevalence in pregnant women in Brazil ranges between 0.1–1.05% by region. An estimated 16,548 HTLV-1 infected women are pregnant each year. According to the breastfeeding pattern and HTLV-1 prevalence of each region there are an estimated 3,024 new cases of HTLV-1 infection due to MTCT annually of which 2,610 are preventable through infant feeding advice. These 3,024 transmissions will result in 120–604 cases of ATL and 8–272 of HAM/TSP. North-East region comprises the high number of MTCT cases, followed by South-East.Conclusions/significanceA high number of new HTLV-1 infections due to MTCT occur every year in Brazil. Antenatal screening and avoiding breastfeeding are essential to prevent subsequent development of HTLV-1-associated diseases.

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“… 7 Living with this disease may generate social isolation and depression. 11 All these features correlate with those of patients with similar neuro-functional conditions in who good results are obtained through physiotherapy. 12 …”

Section: Introductionmentioning

confidence: 64%

Physiotherapy for human T-lymphotropic virus 1-associated myelopathy: review of the literature and future perspectives

Sá¹,

Macêdo²,

Andrade³

et al. 2015

JMDH

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Human T-lymphotropic virus 1 (HTLV-1) infection may be associated with damage to the spinal cord – HTLV-associated myelopathy/tropical spastic paraparesis – and other neurological symptoms that compromise everyday life activities. There is no cure for this disease, but recent evidence suggests that physiotherapy may help individuals with the infection, although, as far as we are aware, no systematic review has approached this topic. Therefore, the objective of this review is to address the core problems associated with HTLV-1 infection that can be detected and treated by physiotherapy, present the results of clinical trials, and discuss perspectives on the development of knowledge in this area. Major problems for individuals with HTLV-1 are pain, sensory-motor dysfunction, and urinary symptoms. All of these have high impact on quality of life, and recent clinical trials involving exercises, electrotherapeutic modalities, and massage have shown promising effects. Although not influencing the basic pathologic disturbances, a physiotherapeutic approach seems to be useful to detect specific problems related to body structures, activity, and participation related to movement in HTLV-1 infection, as well as to treat these conditions.

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Prevalence of anxiety, depression and quality of life in HTLV-1 infected patients

Cited by 26 publications

References 13 publications

Psychiatric Disorders in HTLV-1-Infected Individuals with Bladder Symptoms

Psychiatric Disorders in HTLV-1-Infected Individuals with Bladder Symptoms

Estimation of HTLV-1 vertical transmission cases in Brazil per annum

Physiotherapy for human T-lymphotropic virus 1-associated myelopathy: review of the literature and future perspectives

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